1,011 scientist jobs at 327 companies in Needham, MA

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Scientist-Principal Scientist, Protein Design & Structure
Boston, Massachusetts, United States
OnsiteFull Time
Superluminal Medicines
Superluminal Medicines: Accelerates small molecule drug discovery using generative AI.
2+ YOEPhD in Biochemistry/Molecular Biology/Biophysics with 2+ years (Scientist) or 5+ years (Senior Scientist) or 8+ years (Principal Scientist) of relevant experience in GPCR/membrane protein expression, purification, and characterization; strong leadership and collaboration skills.
Cryo-EM, FPLC, SEC, Rosetta, AI/ML
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Research Scientist
Providence, Rhode Island, United States
$68k-$340k/yr OnsiteFull Time
Brown University Health
Brown University Health: Provides clinical care, medical education, and biomedical research services.
Research scientist role within Brown Health Medical Group; full-time position based in Providence, RI.
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Materials Scientist
Somerville, Massachusetts, United States
$75k-$115k/yr OnsiteFull Time
Formlabs
Formlabs: Develops and manufactures professional-grade 3D printers and materials.
Materials scientist with materials science/polymer development experience, experimental design skills, data analysis, strong documentation, and ability to collaborate with hardware and software teams.
Python, Matlab, SQL, 3D CAD
3w
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Senior Scientist II/Principal Scientist, Sequencing Technologies
Cambridge or Durham
$143k-$215k/yr OnsiteFull Time
Flagship Pioneering
Flagship Pioneering: Conceives, creates, and builds life science platform companies
8+ YOEPh.D. in a relevant field; 8+ years (Senior Scientist II) or 12+ years (Principal Scientist) industry/postdoc experience; deep expertise in NGS, assay development, sequencing operations, automation, and cross-functional leadership.
2mo
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Clinical Translational Scientist
San Francisco or Boston
$130k-$200k/yr OnsiteFull Time
Valius
Valius: Provides precision oncology diagnostics and molecular testing for cancer.
Senior/principal scientist experienced in oncology, translating molecular data into treatment options with strong communication to patients and clinicians.
Oncology, Clinical trial interpretation, Molecular profiling, IHC/mIF, scRNA-seq
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Director, Clinical Scientist
Waltham, Massachusetts, United States
$196k-$240k/yr HybridFull Time
Kailera Therapeutics
Kailera Therapeutics: Developing clinical-stage injectable and oral therapies for obesity.
8+ YOESenior, hands-on clinical scientist lead; 8+ years in clinical trials; strong data review; MD not required; onsite in Waltham, MA.
PowerPoint, Excel, Clinical data systems
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Senior Data Scientist
Boston, Massachusetts, United States
HybridFull Time
Tive
Tive: Provides real-time shipment visibility and condition tracking for logistics.
5+ YOESenior data scientist with 5+ years owning end-to-end ML/AI initiatives; strong Python and SQL skills; experience with dbt, Snowflake or AWS; expertise in statistical modeling, ML/LLM techniques; geospatial/supply-chain/IoT experience preferred.
Python, SQL, dbt, Snowflake, AWS
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Senior Data Scientist
Boston, Massachusetts, United States
$144k-$181k/yr HybridFull Time
CarGurus
CarGurusNASDAQ: CARG: Operates an online marketplace for buying and selling vehicles.
Senior data scientist with ML expertise; strong Python, SQL, AWS SageMaker; experience delivering production ML, data pipelines, and collaboration with cross-functional teams.
Python, SQL, AWS SageMaker, Snowflake
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Scientist
Waltham, Massachusetts, United States
$110k-$150k/yr OnsiteFull Time
BPGbio
BPGbio: AI-powered biopharmaceutical developing biology-first therapeutics and diagnostics.
PhD in chemistry/biology/biochemistry or related field required with hands-on MALDI sample preparation and HRAM mass spectrometer experience; postdoc preferred. Experience in small-molecule analysis, UHPLC-MS/MS, ion mobility-MS, data interpretation, and cross-disciplinary collaboration.
MALDI imaging, HRAM mass spectrometers, Orbitrap mass spectrometers, triple-quadrupole mass spectrometers, UHPLC-MS/MS, ion mobility-MS
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Scientist
Marlborough, Massachusetts, United States
$93k-$108k/yr OnsiteFull Time
IPG Photonics
IPG PhotonicsNASDAQ: IPGP: Develops and manufactures high-performance fiber lasers and systems.
2+ YOEMasters or PhD in biomedical engineering/optics/laser physics, 2+ years R&D experience, hands-on lab and optics/laser/biophotonics skills, data analysis and reporting, MathCad/MatLab/CAD experience, English communication.
MathCad, MatLab, CAD
4h
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Scientist
Cambridge, Massachusetts, United States
$110k-$166k/yr OnsiteFull Time
Alnylam Pharmaceuticals
Alnylam PharmaceuticalsNASDAQ: ALNY: Develops RNAi therapeutics to treat rare and common diseases.
8+ YOEPhD (or MS+8yrs) with experience in LC-MS/MS method development, metabolite/lipid sample prep, omics data analysis, and bioinformatics; familiarity with Python/R and strong communication skills.
LC-MS/MS, triple-quadrupole, high-resolution accurate mass, Sciex QTRAP, Thermo Orbitrap, Python, R, Claude Code, Codex
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Senior Scientist II/Principal Scientist, Sequencing Technologies
Cambridge, Massachusetts, United States
$143k-$215k/yr OnsiteFull Time
Terrana Biosciences
Terrana Biosciences: Develops RNA-based technology for crop protection and enhancement.
8+ YOEPh.D. in a related field required; 8+ years industry/postdoc experience (Senior Scientist) or 12+ years (Principal). Deep expertise in NGS, assay development, sequencing operations, automation, and cross-functional leadership.
Greenhouse
2mo
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Scientist / Sr. Scientist, Research
Waltham, Massachusetts, United States
$142k-$187k/yr OnsiteFull Time
Visterra
Visterra: Develops antibody-based therapies for kidney and immune-mediated diseases.
2+ YOEPhD with 2+ years in industry or BS with 10+ years; hands-on ASO/siRNA design, bioconjugation, cell-based assays, data analysis, CRO/vendor management, mentorship.
qPCR, ddPCR, NGS, Bioconjugation, Linker Chemistry, Cell-Based Assays, Antibody-Oligonucleotide Conjugates
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Scientist/Senior Scientist, Immunology
Cambridge, Massachusetts, United States
$150k-$170k/yr OnsiteFull Time
Raven: Healthcare incubator developing scientific breakthroughs into biotechnology companies.
5+ YOEPhD-level immunologist (or equivalent) with 5+ years industry experience in drug discovery; hands-on expertise in cellular immunology, flow cytometry, ELISA/MSD, cell culture, PK/PD, strong experimental design and communication skills.
flow cytometry, ELISA, MSD
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Senior Data Scientist, Product Analytics
North Bethesda or Waltham
$140k-$160k/yr HybridFull Time
Xometry
XometryNASDAQ: XMTR: Operates an AI-powered marketplace for custom manufacturing and prototyping.
6+ YOESenior data scientist with 6–8 years experience in data analytics, statistics, experimentation, and product analytics; strong SQL; Python and Looker desirable; experience in product-driven environments.
SQL, Python, Looker
3w
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Associate Director, Pharmacovigilance Scientist
Waltham, Massachusetts, United States
$162k-$223k/yr HybridFull Time
Deciphera Pharmaceuticals: Developing targeted kinase inhibitors for the treatment of cancer.
5+ YOE5+ years PV experience (incl. 3+ years as PV Scientist), advanced degree required (PharmD/MD/PhD/MPH/MS/etc.), experience with signal management and aggregate reports, regulatory submission experience (NDA/MAA), strong communication and attention to detail.
Microsoft Office Suite, Argus Safety
2mo
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Senior Scientist - Optical Signal Processing
Woburn or Arlington
$139k-$180k/yr OnsiteFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
3+ YOESenior scientist with 3-5+ years in physics/engineering; degree in physics, applied math, or electrical engineering; proficiency in MATLAB/Python/C/C++; security clearance eligibility; strong communication.
MATLAB, Python, C/C++
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Analytical Science and Technology Senior Scientist
Boston, Massachusetts, United States
$122k-$184k/yr HybridFull Time
Vertex Pharmaceuticals
Vertex PharmaceuticalsNASDAQ: VRTX: Develops and sells prescription drugs for serious genetic diseases.
5+ YOESenior Scientist in Analytical Science; strong analytical chemistry skills; experience with small molecule analytics; method development, transfer, validation, and data trending.
UHPLC, HPLC, GC, KF, spectroscopic identification
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Senior Research Data Scientist
Boston or New York
$330k-$375k/yr HybridFull Time
Roku
RokuNASDAQ: ROKU: Operates a TV streaming platform and sells streaming hardware.
10+ YOEPhD-preferred research data scientist with 10+ years applying causal inference and ML to large observational datasets; expertise in observational causal methods, communication skills, and productionizing pipelines.
Spark, Ray, SQL, Python, scikit-learn, XGBoost, LightGBM
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Associate Scientist / Scientist, Immunology & Pharmacology
Bedford, Massachusetts, United States
OnsiteFull Time, Temporary
PharmaEssentia
PharmaEssentiaTaiwan Stock Exchange: 6446: Develops and provides biologics for hematology and oncology.
2+ YOEDesign and execute in vitro/ex vivo/in vivo immunology and pharmacology studies; 2+ years relevant research experience; B.S./M.S./Ph.D. in relevant field; experience with primary immune cell assays and immuno-oncology preferred.
multicolor flow cytometry, FACS, ELISA, Meso Scale Discovery (MSD)