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155 senior fastapi developer jobs at 109 companies in California

3mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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2mo
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Senior Software Engineer, App
Cambridge or San Francisco
$144k-$240k/yr HybridFull Time
Lila Sciences
Lila Sciences: Develops an AI platform for autonomous scientific research and discovery.
5+ YOEBachelor’s or Master’s in CS/Engineering; 5-8+ years backend/full-stack exp; React, TypeScript, FastAPI, Python; AWS, Kubernetes; AI tooling; strong collaboration.
React, TypeScript, Nx, Tailwind, FastAPI, Python, Pydantic, SQL, NoSQL, AWS, Kubernetes, Terraform, GitHub Actions
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2w
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Senior Engineer
Santa Clara, California, United States
$120k-$150k/yr OnsiteFull Time
Tata Consultancy Services
Tata Consultancy ServicesNational Stock Exchange of India: TCS: Global provider of IT services, consulting, and business solutions.
6+ YOEExpertise in Python or Java, full-stack development (Next.js/React/TypeScript), GraphQL and FastAPI backend, prompt engineering and GenAI tooling, cloud deployment on AWS/Azure, and bachelor's degree or equivalent.
Python, Java, Ariadne(GraphQL), appoloClientGraphQL, FastAPI, Next.js, React, TypeScript, Javascript, GitHub Copilot, Amazon Code Whisperer, GPT-4, Claude, Llama, AWS Lambda, S3, EC2, SageMaker, Azure Functions, Blob Storage, Azure OpenAI Service
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2mo
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Senior Backend Engineer
San Francisco, California, United States
$175k-$275k/yr OnsiteFull Time
Hedra
Hedra: Builds artificial intelligence models for character-driven video generation.
5+ YOE5+ years backend development with Python, FastAPI/Pydantic; Kubernetes/EKS; relational databases; AWS stack; building scalable services.
Python, FastAPI, Pydantic, Kubernetes, EKS, PostgreSQL, Redis, S3, DynamoDB, AWS
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3mo
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Senior Software Engineer, AI
El Segundo or United States
$153k-$170k/yr RemoteFull Time
ImmunityBio
ImmunityBioNASDAQ: IBRX: Develops next-generation immunotherapies for cancer and infectious diseases.
7+ YOESenior software engineer with 7+ years of experience in Python/Typescript, AI agent frameworks, and production-grade systems.
Python, TypeScript, FastAPI, Docker, LangGraph, LangChain, CrewAI, LlamaIndex, Chroma, Milvus, Weaviate, Qdrant
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1mo
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Senior Software Engineer
New York City or Arizona or California or Colorado or Connecticut or Florida or Georgia or Maine or Maryland or Massachusetts or Michigan or Minnesota or New Jersey or New York or North Carolina or Oregon or Rhode Island or South Carolina or Tennessee or Texas or Virginia or Utah or Wisconsin
$165k-$185k/yr RemoteFull Time
Electric
Electric: Provides automated IT management and security services for businesses.
8+ YOE8+ years backend experience with modern Python stack, leadership experience, proficiency in Postgres/SQLAlchemy, AWS, Terraform, FastAPI, React/TypeScript, observability, and familiarity with AI-assisted development.
Python, FastAPI, Pydantic, PostgreSQL, SQLAlchemy, Alembic, Temporal, Redis, AWS RDS, AWS S3, AWS SQS, AWS DynamoDB, AWS ECS, AWS IAM, Terraform, React, TypeScript, Claude Code
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3w
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Senior Backend Software Engineer
Arkansas or California or Colorado or District of Columbia or Florida or Illinois or Massachusetts or Maryland or Maine or Michigan or New Jersey or Ohio or Pennsylvania or South Carolina or Texas or Utah or Virginia or Washington
$165k-$195k/yr RemoteFull Time
SITE Technologies
SITE Technologies: Provides AI-powered property condition assessments and management software.
5+ YOE5+ years backend development experience with Python and FastAPI, strong backend architecture, relational modeling, AWS services, Docker, CI/CD, and cross-team communication.
Python, FastAPI, PostgreSQL, SQLAlchemy, Alembic, Flyway, AWS, ECS, Lambda, RDS, S3, IAM, Docker, Git, CI/CD, GitHub Actions, AWS CodePipeline, Claude Code, Cursor, Terraform, Terragrunt, Datadog, Sentry, LangGraph, Claude Code SDK, Amazon Bedrock
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1mo
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Senior Software Engineer - Python
Toronto or San Francisco
$130k-$225k/yr RemoteFull Time
Veeva Systems
Veeva SystemsNYSE: VEEV: Cloud-based software solutions for the global life sciences industry.
5+ YOE5+ years software development with production-level Python, enterprise SaaS/scale experience, proficiency with Python, Git, FastAPI, Pydantic, strong communication and mentorship skills, and unrestricted right to work in the U.S.
Python, Git, FastAPI, Pydantic
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Senior Full Stack Software Engineer
Redwood City, California, United States
HybridFull Time
GridCARE
GridCARE: Unlocking electrical grid capacity for AI data center power.
Senior-level experience building production web applications with TypeScript and modern frontend frameworks; backend experience with Python/FastAPI and relational databases; strong product judgment and collaboration skills.
TypeScript, Next.js, React, Vite, Python, FastAPI, PostgreSQL
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2mo
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Senior Software Engineer
San Francisco, California, United States
$146k-$235k/yr HybridFull Time
DocuSign
DocuSignNASDAQ: DOCU: Provides electronic signature and agreement management software solutions.
8+ YOEBachelor's in CS or STEM with 8+ years of software engineering experience; full-stack with Java/JavaScript-TS, React; experience with Oracle Fusion Cloud APIs, OIC, Python, AI/ML, cloud-native tech, and CI/CD.
Java, JavaScript, TypeScript, React, OIC, VBCS, APEX, Groovy, PL/SQL, Oracle Fusion Cloud APIs, Python, Django, FastAPI, REST, SOAP, JSON/XML, Docker, Kubernetes, AWS, Azure, Oracle OCI, Jira, Confluence, GitHub Co-Pilot, LLMs, MLOps, RAG
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1mo
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Senior Software Engineer
Boston or Encinitas
$142k-$192k/yr OnsiteFull Time
Paperless Parts
Paperless Parts: Cloud-based quoting software for custom part manufacturers.
5+ YOE5+ years experience building full-stack web applications; strong Python (Django/FastAPI), TypeScript/React, AWS, PostgreSQL, Docker, and CI/CD (Jenkins) experience; API design and mentoring skills; US citizenship or green card required.
Python, Django, FastAPI, TypeScript, React, PostgreSQL, AWS, Docker, Jenkins, Node/Express, Java/Spring
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2mo
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Senior Research Engineer - Experimental Engineering
Yonkers or Washington or Colchester or Arizona or California or Connecticut or Illinois or Maryland or Massachusetts or Michigan or New Hampshire or New Jersey or New York or Texas or Vermont or Virginia or District of Columbia
$115k-$160k/yr RemoteFull Time
Consumer Reports
Consumer Reports: Tests products and publishes ratings for consumer advocacy.
Senior research engineer with deep full-stack software engineering experience, strong applied AI/ML knowledge, prototyping and R&D experience, Python/FastAPI and frontend (React/React Native) familiarity, and ability to lead experiments and mentor engineers.
AI, Machine Learning, Python, FastAPI, React, React Native, RAG
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1mo
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Senior AI Engineer
United States or New York City or Palm Beach or Los Angeles or Miami or Greenwich or Westchester County or The Hamptons or San Francisco or Manhattan
$190k-$250k/yr RemoteFull Time
Atria Health Institute
Atria Health Institute: Membership-based concierge practice providing preventive, precision-based medical care.
4+ YOE4+ years building and operating LLM-powered production ML systems, strong Python, backend framework experience (FastAPI/Flask), LLM orchestration and retrieval design, Snowflake/dbt/Dagster/Airflow familiarity, evaluation systems, HIPAA/PHI knowledge, and strong written communication.
Python, FastAPI, Flask, Snowflake, dbt, Dagster, Airflow, vLLM, Triton, TGI, SGLang, LOINC, SNOMED CT, ICD-10, RxNorm, FHIR, HL7
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3mo
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Senior Fullstack Engineer, Solve
Austin or Madison or San Francisco
$145k-$217k/yr HybridFull Time
Zendesk
Zendesk: Provides cloud-based software for customer service and support.
3+ YOE3+ years of production software experience; backend-first with APIs, async systems, integrations, and real-time systems; ownership of features end-to-end; experience with real-time or event-driven tech such as WebSockets/WebRTC.
Python, FastAPI, React, TypeScript, WebRTC, Redis, MongoDB, LLM / speech
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2mo
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Staff Platform Engineer (Pacific Time Zone)
San Francisco, California, United States
$225k-$275k/yr HybridFull Time
Komodo Health
Komodo Health: Provides AI-driven healthcare data and patient journey analytics software.
Senior backend engineer with platform and control-plane experience; strong Python (FastAPI) and AWS; multi-tenant SaaS; focus on observability, reliability, and developer productivity.
Python, FastAPI, AWS, Snowflake, Airflow, Spark, RBAC, API design, KMC/PSS
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4w
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Senior Software Engineer, Full-Stack
San Francisco, California, United States
$170k-$230k/yr HybridFull Time
Roger Healthcare
Roger Healthcare: AI clinical documentation platform for home health clinicians.
7+ YOE7+ years software engineering experience with deep backend expertise; experience with distributed systems, production LLM/Generative AI systems, FastAPI, MongoDB/Postgres, Docker, and AWS; strong communication and product mindset.
FastAPI, MongoDB, Postgres, Docker, AWS, LLMs, Generative AI
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1mo
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Senior Professional Software Engineer (Python)
Irvine or Oklahoma City or Sunrise or Oxford or Dallas or Austin
$129k-$165k/yr HybridFull Time
Cotality
Cotality: Provider of property intelligence, data, and analytics solutions.
5+ YOEBachelor's or Master's in Computer Science/AI or related, 5+ years software engineering, expert Python/FastAPI, microservices, Snowflake/Databricks, cloud (GCP/AWS/Azure), Agile (Jira/Confluence), strong communication and mentoring skills.
Python, FastAPI, Snowflake, Databricks, GCP, AWS, Azure, Jira, Confluence, YAML
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Senior Software Engineer, Engine & Distributed Systems
San Francisco or New York City
$220k-$240k/yr HybridFull Time
StackAI
StackAI: Build and deploy custom AI agents without writing code.
5+ YOE5+ years building backend distributed systems; experience with durable execution/workflow orchestration (Temporal, Cadence, Airflow), strong Python and FastAPI skills, Postgres familiarity, concurrency, fault tolerance, and recovery.
Temporal, Cadence, Airflow, Python, FastAPI, Postgres, PydanticAI, LangGraph
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1mo
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Senior Software Engineer - Full Stack, Technical Lead
San Francisco, California, United States
$200k-$250k/yr HybridFull Time
Baton
BatonNYSE: R: Builds AI software to automate and optimize supply chains.
5+ YOE5+ years full-stack experience; advanced Python; frontend with React and TypeScript; backend experience with GraphQL/FastAPI; Postgres and AWS familiarity; proven technical project leadership and mentorship.
Python 3, GraphQL, FastAPI, React, TypeScript, Postgres, AWS
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1d
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Copy of Senior Software Engineer, Identity Graph
San Francisco, California, United States
$230k-$340k/yr HybridFull Time
Baselayer
Baselayer: AI-powered business identity and risk verification platform.
Proven experience shipping end-to-end product features (ingestion→storage→API), strong async Python, deep Postgres expertise, FastAPI/OpenAPI experience, and multi-tenant API and schema ownership.
Postgres, Python, FastAPI, OpenAPI, GCP, Cloud Run, Cloud Tasks, Cloud SQL
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