23 senior python developer jobs at 16 companies in Lake Jackson, TX

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
2mo
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Senior Security Engineer
Houston, Texas, United States
OnsiteFull Time
Landry's
Landry's: Operates national restaurant, hospitality, and gaming entertainment venues.
3+ YOE3-5 years in information security across endpoint, network, cloud, and identity; hands-on EDR, firewall, ZTNA, CIEM, SIEM; PCI DSS; scripting with Python/PowerShell; preferred CISSP/GPEN/CCSP, hospitality/gaming industry experience.
Endpoint Detection and Response, Next-Generation Firewall, Zero Trust Network Access, Secure Web Gateway, SIEM, Python, PowerShell, MFA, Cloud IAM, Vulnerability Management, BEC protection, Bug bounty
1mo
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Senior Programmer Analyst (Reinsurance / AI / Python Focus)
League City, Texas, United States
OnsiteFull Time
American National
American National: Provides insurance, annuities, and retirement services to customers.
Professional application development experience (not entry-level); hands-on Python and/or Java; experience applying AI/LLMs; familiarity with data platforms (Databricks, SQL Server, SSIS, Azure Cosmos DB); cloud/DevOps (Azure, Docker, AKS) preferred.
Python, Java, Databricks, Microsoft SQL Server, SSIS, Azure Cosmos DB, Pandas, NumPy, ZEKE, ZENA, Azure Functions, Docker, AKS, Azure DevOps, Rust, Large language models (LLM)
1mo
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Senior AI Engineer
Spring or Fort Collins
$137k-$315k/yr HybridFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Provides edge-to-cloud IT infrastructure and platform services.
3+ YOE3+ years of software engineering; experience with AI coding tools; automation tooling; Git/CICD workflows; strong communication; growth mindset.
Python, Git, GitHub Copilot, ChatGPT, Claude, CI/CD, Scripting
1mo
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Senior Forward Deployed AI Engineer
Houston, Texas, United States
RemoteFull Time
Archer Systems
Archer Systems: Provides administrative services for complex legal settlement programs.
5+ YOE5+ years building production software or AI solutions; experience with Palantir Foundry/AIP, Copilot Studio/Power Platform; strong API/integration; Python, JavaScript/TypeScript, SQL; ability to work with stakeholders.
Palantir Foundry, AIP, Copilot Studio, Power Platform, Claude Code, Claude CoWork, SQL, Python, JavaScript, TypeScript, NetSuite, SharePoint
2d
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Test Automation Engineer
Omaha or Albany or League City or Chicago
$80k-$110k/yr OnsiteFull Time
Brookfield Wealth Solutions
Brookfield Wealth SolutionsNYSE: BNT: Provides wealth protection, retirement services, and specialty insurance solutions.
6+ YOE6+ years software development/test automation experience with 5+ years building automated frameworks; proficiency in languages and frameworks listed; strong problem-solving and mentoring skills.
Java, Python, JavaScript, TypeScript, C#, Selenium, Cypress, Playwright, Tricentis Tosca, GitHub Actions, Azure DevOps
1d
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Full Stack Web Developer
Stafford, Texas, United States
OnsiteFull Time
Eurofins Scientific
Eurofins ScientificEuronext Paris: ERF: Global provider of analytical testing and laboratory services.
5+ YOEBachelor's or equivalent,5+ years full-stack web development,experience with ASP.NET,Blazor,Angular,Microsoft Azure,Azure DevOps,HTML/CSS/JavaScript/TypeScript,REST APIs,and relational databases.
ASP.NET, Blazor, Angular, Microsoft Azure, Microsoft Azure DevOps, HTML, CSS, JavaScript, TypeScript, REST APIs, SQL, Python, Django, Entity Framework, Microsoft SQL Server, PostgreSQL
2mo
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Sr HPC Engineer
Houston, Texas, United States
OnsiteFull Time
Baylor Genetics
Baylor Genetics: Provides clinical genetic testing and genomic sequencing services.
8+ YOE4+ MgmtSenior HPC engineer with 8+ years in bioinformatics software, HPC, Nextflow, containerization, and cloud in genomics. Leadership experience.
Nextflow, Slurm, Docker, Apptainer, Git, CI/CD, Azure, AWS, Python, Bash, R, Linux/Unix
3w
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Orion GN&C Engineer
Houston, Texas, United States
RemoteFull Time
Astrion
Astrion: Provides engineering, cybersecurity, and mission support services.
5+ YOEBachelor's-level engineering background, experience developing safety-critical flight software and GN&C algorithms. Strong MATLAB/Simulink/Stateflow/Autocode, C/C++, and Python skills. U.S. citizenship and background check required.
MATLAB, Simulink, Stateflow, Autocode, C, C++, Python, TRICK, JEOD
1mo
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NDT Development Engineer
Houston, Texas, United States
OnsiteFull Time
NOV
NOVNYSE: NOV: Manufactures and provides equipment for the energy industry.
5+ YOEBachelor's in engineering/physics/math, 5+ years NDT/UT or inspection engineering experience, skilled with ultrasonic and electromagnetic methods, data acquisition and signal processing familiarity, programming (Python, MATLAB, C++, C#) preferred.
Python, MATLAB, C++, C#, COMSOL, ANSYS
1mo
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Lead Analyst Data Engineer
Houston, Texas, United States
OnsiteFull Time
Boardwalk Pipelines
Boardwalk Pipelines: Transporting and storing natural gas and liquids via pipelines.
7+ YOE7+ years cloud data architecture experience (5+ years AWS), proficiency with AWS services and Databricks, strong SQL/Python skills, experience with data governance and mentoring engineers; Bachelor’s required, Master’s preferred.
Glue, Redshift, Athena, Lake Formation, SageMaker, Bedrock, Step Functions, Databricks, Alation, SQL, T-SQL, Python, PySpark, Pandas, DAX, Microsoft Power Query (M), PL/SQL, Microsoft SQL Server, Oracle, PostgreSQL, Microsoft Azure SQL, Teradata, Microsoft Power BI, Git, Microsoft Visual Studio Code, SSMS
2mo
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AI Automation Engineer
Bellaire, Texas, United States
OnsiteFull Time
Matrix Medical Management
Matrix Medical Management: Provides administrative and business management services to medical practices.
5+ YOE5+ years in digital transformation or process improvement with 2+ years shipping production solutions on Microsoft Power Platform or LLMs; hands-on Power Apps/Power Automate/Power BI, Dynamics 365, Microsoft 365 Copilot, Python/JavaScript; healthcare operations and AI governance knowledge.
Microsoft Power Apps, Microsoft Power Automate, Microsoft Power BI, Microsoft Dynamics 365, Microsoft 365 Copilot, Python, JavaScript, Claude, Microsoft Entra ID, Microsoft Purview, Microsoft 365 audit logs
3mo
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Electronics Design Engineer - Space Exploration Electronic Systems
Houston or Clear Lake Shores
HybridFull Time
Oceaneering
OceaneeringNYSE: OII: Global provider of engineered services for offshore energy industries.
10+ YOEBachelor's in Engineering; 10-15 years space electronics experience; lead electronics design teams; PCB design; LabVIEW; NASA standards.
Altium Designer, Subversion (SVN), LabVIEW, VHDL, Xilinx Vivado, C, C++, Python, Pspice, OrCAD, Multisim
3w
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Senior Research Scientist, Anesthesiology
Galveston, Texas, United States
OnsiteFull Time
University of Texas Medical Branch
University of Texas Medical Branch: Public academic health science center providing healthcare and education.
3+ YOEPhD plus 3–5 years related experience. Experience with PET/CT imaging, animal and human studies, signal/image processing, mathematical modeling, and programming (MATLAB, Python, LabView).
Positron Emission Tomography (PET), Computed Tomography (CT), MATLAB, Python, LabView, AI
1mo
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Senior Director, Chief Actuary (Medicare Advantage) - Kelsey - Seybold Clinics, Houston, TX
Houston or Pearland
$159k-$273k/yr OnsiteFull Time
UnitedHealth Group
UnitedHealth GroupNYSE: UNH: Provides health insurance and technology-enabled health care services.
10+ YOE8+ MgmtBA/BS in relevant field; ASA or FSA; 10+ years experience including 5+ as a healthcare actuary and 8+ years managing teams; 3+ years Medicare Advantage bid development; 3+ years programming in SQL, SAS, or Python; knowledge of IBNR and PMPM modeling.
SQL, SAS, Python, Crystal Reports, Microsoft Access, EPIC, Clarity
2mo
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Nuclear Physicist
Sugar Land, Texas, United States
OnsiteFull Time
SLB
SLBNYSE: SLB: Provides global oilfield services, equipment, and digital energy solutions.
PhD in Nuclear Engineering or Physics; experience with nuclear measurements; programming in Python/Matlab/C++; strong problem-solving and communication; export-control aware.
Python, Matlab, C++
2mo
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Nuclear Physicist
Sugar Land, Texas, United States
OnsiteFull Time
SLB
SLBNYSE: SLB: Global provider of technology and services for energy industry
Ph.D. in nuclear engineering/physics or related field; experience with experiment and modeling of nuclear radiation data; programming in Python, MATLAB, C++; strong problem-solving, communication, and mentorship skills; ability to access export-controlled information.
Python, MATLAB, C++
3w
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Permit Supervisor (Drafting)-Telecommunications
Iron Mountain or Front Royal or Iron River or Tifton or Sylacauga or Charlevoix or Cheboygan or Galveston or Corpus Christi or Henderson or Gainesville or Hollywood or Pembroke Pines or Fort Lauderdale or Hialeah or St. Petersburg or Sandy Springs or Athens or Augusta or Gulfport or Richmond or Covington or Alexandria
OnsiteFull Time
CCI Systems
CCI Systems: Provides telecommunications infrastructure engineering and technical support services.
6+ YOE2+ Mgmt6+ years CAD drafting experience with 2+ years supervising CAD teams; expert AutoCAD skills, CAD standards development, QA/QC, AutoLISP/.NET/C#/Python automation, Revit/Civil 3D interoperability, PDM/EDMS experience, and leadership/project planning.
AutoCAD, Sheet Set Manager, AutoLISP, .NET, C#, Python, Revit, Civil 3D, Plant 3D, Navisworks, IFC, DGN, DWG, Autodesk Vault, ProjectWise

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