28,033 senior python developer jobs at 6,024 companies in United States

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
3mo
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Senior Python Engineer, AI
United States
$119k-$206k/yr RemoteFull Time
eBay
eBayNASDAQ: EBAY: Global online marketplace for buying and selling diverse products.
5+ YOE5+ years Python backend development; experience building asynchronous microservices, APIs, and AI/LLM integrations; strong communication and cross-functional collaboration.
Python, FastAPI, asyncio, REST API, CI/CD, Docker, Kubernetes, Git
3mo
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Senior Python Engineer
United States
$200k-$225k/yr RemoteFull Time
Wizard
Wizard: Provides an AI agent for searching and buying products.
5+ YOE5+ years backend software engineering; strong Python; API design; production ML/AI experience; cloud platforms; Docker/Kubernetes.
Python, AWS, GCP, Azure, Docker, Kubernetes, SQL, NoSQL, LLMs, ML
3w
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Senior Python Developer
Herndon, Virginia, United States
OnsiteFull Time
ManTech
ManTech: Provides technology solutions for defense and intelligence agencies.
10+ YOE10+ years Python development, SQL, front-end/full stack, Git, Docker/Kubernetes, RESTful API development, Linux/Unix; Bachelor's in CS +10 years or HS +14 years; active TS/SCI with polygraph required.
Python, SQL, Git, Docker, Kubernetes, RESTful API, Linux/Unix, Node.js, Jenkins, GitLab CI, AWS, Azure, JIRA
1mo
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Senior Python Engineer (.NET)
United States
RemoteFull Time
ShiftKey
ShiftKey: Marketplace connecting healthcare facilities with independent licensed professionals.
Production-grade Python (3.10+) and meaningful .NET experience, hands-on AI/LLM agent development workflows, senior judgment, and strong collaboration for remote US work.
Python, .NET, Claude Code, LLM
1mo
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Senior Python Developer
Washington or Virginia or Maryland
$90k-$130k/yr OnsiteFull Time
Tripoint Solutions
Tripoint Solutions: Providing technology modernization and data services to federal agencies.
5+ YOEBachelor's in CS or related, 5+ years Python development, experience with Django/Flask, REST APIs, PostgreSQL, Git, Unix/Linux, AWS/Cloud platforms, Jupyter Notebooks; U.S. citizenship and eligibility for Federal Public Trust required.
Python, Django, Flask, Jupyter Notebook, Git, PostgreSQL, Unix/Linux, HTML, JavaScript, Docker, Kubernetes, AWS, Cloud Foundry, Heroku, ServiceNow, UiPath
2mo
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Senior Developer (Python)
Moonachie, New Jersey, United States
$75k-$100k/yr OnsiteFull Time
Content Critical Solutions
Content Critical Solutions: Provider of high-volume printing, mailing, and document fulfillment services.
3+ YOESenior Python developer with 3-5 years Python, SQL, data processing, XML/JSON, and data transformation for transactional mail workflows; strong communication; capable of independent delivery.
Python, SQL, XML, JSON, Postscript, PDF, AFP, PCL, Windows, Linux, Perl, Shell scripting
1mo
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Senior Python Engineer
Quantico, Virginia, United States
OnsiteFull Time
SAIC
SAICNYSE: SAIC: Provides engineering, IT, and mission support services to government.
9+ YOEU.S. citizen with active Top-Secret clearance, Bachelor's (or equivalent) and 9+ years' experience; 3–5 years Python development; IAT-II/Security+ CE; experience with Django/Flask, API development, Git, databases/ORMs, security best practices.
Python, Django, Flask, Git
1mo
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Senior Python Engineer
Quantico, Virginia, United States
OnsiteFull Time
SAIC
SAICNASDAQ: SAIC: Provides government and defense clients with technology and engineering services.
9+ YOEBachelor's (or equivalent) and 9+ years experience, U.S. citizenship with active Top-Secret clearance, IAT-II (Security+ CE), 3–5 years Python development, Django/Flask, API integration, Git, database/ORM knowledge.
Python, Django, Flask, Git
1w
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Senior Python Developer
United States
$125k-$208k/yr OnsiteFull Time
Deloitte
Deloitte: Provides professional audit, consulting, advisory, and tax services.
6+ YOE6+ years Python experience with concurrency, REST APIs, strong SQL, Apache Spark knowledge, bachelor's degree preferred; ability to travel ~10%; limited immigration sponsorship available.
Python, SQL, RESTful APIs, Apache Spark, Spark SQL, OAuth
1mo
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Senior Python Developer
New York City, New York, United States
$121k-$182k/yr HybridFull Time
Citi
CitiNYSE: C: Providing global banking, investment, and wealth management services.
5+ YOE5+ years experience; bachelor\u0002s or equivalent in CS/Engineering/Math preferred; extensive Python and container orchestration knowledge; experience with systems analysis, programming, project delivery, and applying AI/GenAI.
Python, Docker, Kubernetes, OpenShift, AI, GenAI, CI/CD
1mo
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Senior Python Developer
New York City, New York, United States
$121k-$182k/yr HybridFull Time
Citi
CitiNYSE: C: Global diversified financial services holding.
5+ YOE5+ years experience; Bachelor's in CS/STEM preferred; extensive Python; experience with Docker, Kubernetes, OpenShift; systems analysis, programming, CI/CD, project implementation, and working with AI/GenAI integrations.
Python, Docker, Kubernetes, OpenShift, AI, GenAI, CI/CD
1mo
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Senior Python Engineer
Alpharetta or United States
OnsiteFull Time
Solifi
Solifi: Unified SaaS platform for secured finance and lending operations.
5+ YOEBachelor's preferred, 5+ years software engineering experience building cloud-native Python backend services and REST APIs; strong SQL and AWS experience; familiarity with Python web frameworks and testing/observability practices.
Python, FastAPI, Flask, Django, Angular, SQL, AWS, Lambda, ECS/Fargate, EC2, API Gateway, S3, RDS, Redshift, Postgres, Snowflake, Databricks, Parquet, Avro, ORC, SNS, SQS, Kafka, Kinesis, Terraform, CloudFormation, CDK, Docker, .NET, C#, CI/CD
2mo
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Spatial Front, Inc - Senior Python Developer
United States
$100k-$150k/yr RemoteFull Time
Spatial Front
Spatial Front: IT solutions and mission support for government agencies.
10+ YOE10+ years software development; 5+ years Python; 3+ years SQL/Relational databases; 3+ years Linux/Unix; U.S. work authorization with ability to obtain Public Trust clearance.
Python, SQL, Oracle, PostgreSQL, Linux, GeoPandas, ArcGIS
3mo
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Senior‑Level Python Developer (Python, C++)
Annapolis Junction, Maryland, United States
$155k-$175k/yr OnsiteFull Time
IDS International
IDS International: Global training, logistics, and security for government agencies.
8+ YOEBachelor’s degree in computer science; 8+ years relevant experience; Python, C++, Spark; Jupyter Notebooks; JIRA, Confluence, Git/GitLab; knowledge of customer tools; active TS/SCI with Polygraph.
Python, C++, Spark, Jupyter Notebooks, JIRA, Confluence, Git/GitLab
2mo
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Python Senior Developer - DevOps (106340)
United States
OnsiteFull Time
HCLTech
HCLTechNational Stock Exchange of India: HCLTECH: Global provider of information technology services and software consulting.
Develop and implement DevOps solutions using Python and GitHub; strong Python scripting, CI/CD knowledge, version control, collaboration, problem solving; DevOps certifications preferred.
Python, GitHub
2d
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Senior Python Engineer
New York City, New York, United States
RemoteFull Time
DeweyLearn
DeweyLearn: AI-powered platform providing insights for educational teaching and learning.
5+ YOE5+ years professional Python experience, FastAPI and PostgreSQL production experience, Docker, EM/CI-CD fundamentals, experience with ML/AI and retrieval workflows preferred; fluent English.
Python, FastAPI, PostgreSQL, Docker, CI/CD
6d
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Senior Python AI/ML Developer
Jersey City, New Jersey, United States
OnsiteFull Time
Virtusa
Virtusa: Global provider of digital engineering and IT outsourcing services.
8+ YOEBachelor's degree or equivalent,8+ years software development experience,proficient in Python,web frameworks,REST,relational and NoSQL databases,async processing,and Git.
Python, Django, Flask, FastAPI, PostgreSQL, MySQL, Oracle, MongoDB, DynamoDB, Redis, Git
2mo
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Senior Angular/Python Engineer
Merrimack, New Hampshire, United States
OnsiteFull Time
Fidelity Investments
Fidelity Investments: Provides investment management, retirement planning, and brokerage services.
4+ YOEBS in Computer Science or equivalent; 4+ years of experience; Angular frontend; Python/SQL; AWS/Azure; CI/CD/DevOps; strong collaboration and learning.
Angular, Python, SQL, Excel VBA, Power Platform, AWS, Azure, CI/CD, DevOps
1mo
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Senior Java/Python Developer
Middletown, New Jersey, United States
$100k-$110k/yr OnsiteFull Time
Tech Mahindra
Tech MahindraNational Stock Exchange of India: TECHM: Global provider of information technology and business process services.
5+ YOEBachelor's degree required; 5+ years experience; strong Java and Python backend development, REST/microservices, system architecture, unit/integration testing and CI/CD experience.
Java, Python, RESTful APIs, CI/CD pipelines
1mo
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Python Developer (Mid-Senior)
Chantilly, Virginia, United States
OnsiteFull Time
JTEC Consulting
JTEC Consulting: Provides IT services to federal clients.
10+ YOE10+ years Python development; FastAPI; AWS; TS/SCI with polygraph; U.S. citizenship; Bachelor's degree or equivalent experience; on-site in Chantilly, VA.
Python, FastAPI, SQLAlchemy, AWS, Kubernetes, Jenkins, GitHub, OpenSearch, Elastic, Airflow, PySpark, Trino, Linux, Docker, Helm, Makefiles, Java, Perl, C, C++, HTML, JavaScript, JSON