283 senior scientist jobs at 126 companies in Lake Forest, CA

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Senior Scientist, Biologics Formulation
El Segundo, California, United States
$140k-$180k/yr OnsiteFull Time
Varda Space Industries
Varda Space Industries: Develops in-orbit manufacturing platforms and reentry capsules for pharmaceuticals.
3+ YOEPhD in a relevant field; 3+ years protein formulation development; deep protein chemistry and biophysics expertise; hands-on analytics; independent in fast-paced startup; strong scientific writing.
Dynamic Light Scattering, Differential Scanning Calorimetry, Size Exclusion Chromatography, Capillary Electrophoresis, Rheology, Spectroscopy
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Senior Scientist / Engineer
Los Angeles, California, United States
OnsiteFull Time
Arcturus
Arcturus: Develops carbon nanomaterial-infused metal composites for high-performance conductors.
3+ YOE3+ years in materials R&D, processing, or additive manufacturing; hands-on experimental focus; strong documentation and data analysis.
Raman spectroscopy, SEM/EDS, Optical microscopy, Electrical testing, Thermal testing, Hardness testing, CVD/LCVD, Laser processing, LPBF, DED
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Senior Scientist
Carlsbad, California, United States
$78k-$117k/yr OnsiteFull Time
Merck KGaA, Darmstadt, Germany
Merck KGaA, Darmstadt, GermanyFrankfurt Stock Exchange: MRK: A science and technology in healthcare, life sciences, and electronics.
8+ YOEBachelor’s degree in chemistry, biochemistry, biology, or life sciences plus 8+ years in GMP or QC laboratory settings; expertise in analytical testing, method validation, cGMP, and ICH guidelines.
qPCR, ddPCR, HPLC, CE-SDS, ELISA, HPLC/UPLC
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Senior Scientist
Carlsbad, California, United States
$78k-$117k/yr OnsiteFull Time
Merck
MerckXETRA: MRK: A science and technology providing healthcare, life science, and electronics solutions.
8+ YOEBachelor's degree in chemistry, biochemistry, or life science and 8+ years in GMP or QC laboratories; analytical method validation, cGMP, ICH, QA/QC, and biologics experience preferred.
qPCR, ddPCR, HPLC, CE-SDS, ELISA, UPLC, SOPs, CAPAs
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Senior Scientist
Pasadena or Sudbury or Chicago or Tampa or Phoenix
$105k-$120k/yr HybridFull Time
Advocates for Human Potential
Advocates for Human Potential: Provides consulting and research services for human services systems.
5+ YOEPh.D.,5+ years leading evaluation-focused proposals and projects, expertise in substance use/rural health/criminal justice, experience with federal contracts and SAMHSA data tools.
Stata, REDCap, Dedoose, Microsoft Word, Microsoft Outlook, Microsoft PowerPoint, Microsoft Excel, citation management software
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Senior Scientist
Pasadena, California, United States
$134k-$165k/yr OnsiteFull Time
Caltech
Caltech: Provides university-level education and scientific research services.
10+ YOE8+ MgmtBS in Physics, Astronomy, or Engineering; 10+ years high-precision optics experience; 8+ years mentoring; expertise in optical design, coatings, and precision optical metrology; MS/PhD preferred; MS Project experience preferred.
Microsoft Project
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Senior Scientist
Carlsbad, California, United States
$78k-$117k/yr OnsiteFull Time
Merck KGaA
Merck KGaAFrankfurt Stock Exchange: MRK: Develops pharmaceutical, life science, and electronics technologies.
8+ YOEBachelor’s degree in chemistry, biochemistry, or life science; 8+ years in GMP or QC laboratory environments; analytical method validation, transfer, documentation, and cGMP compliance experience.
qPCR, ddPCR, HPLC, CE-SDS, ELISA, UPLC, SOPs, PPE, QA, QC, CAPAs
2mo
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Senior Scientist
Monrovia, California, United States
$90k-$120k/yr OnsiteFull Time
ChromoLogic
ChromoLogic: Develops and commercializes disruptive medical, aerospace, and security technologies.
PhD in a relevant engineering or chemistry field; background in hollow fiber membranes, filtration, separations, or bioprocessing; experimental design, data analysis, failure analysis; lab testing and prototype experience; strong communication.
1d
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Senior Scientist, Chemistry
South San Francisco or United States or Puerto Rico or San Francisco or Los Angeles or Rahway
$131k-$207k/yr OnsiteFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Develops and manufactures prescription medicines, vaccines, and animal health products.
4+ YOERequires a chemistry degree and 4–7 years of experience depending on degree level, with extensive organic synthesis expertise, analytical skills, complex problem-solving, collaboration, and communication abilities.
chromatography, mass spectrometry, spectroscopy, Process Analytical Technology (PAT)
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Temp Senior Research Associate/Sr Scientist, Formulation and Delivery Sciences
Carlsbad or Boston or Dublin
$42-$75/hr OnsiteFull Time, Temporary
Ionis Pharmaceuticals
Ionis PharmaceuticalsNASDAQ: IONS: Discovers and develops RNA-targeted medicines for serious diseases.
2+ YOERequires BS and 5+ years of laboratory experience for Senior Research Associate or PhD and 2+ years for Senior Scientist, plus RNA-loaded LNP synthesis, nanoparticle characterization, and laboratory communication skills.
HPLC, Ribogreen, DLS, SEC
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Senior Scientist
Torrance, California, United States
$90k-$100k/yr OnsiteFull Time
The Lundquist Institute
The Lundquist Institute: Conducts independent biomedical research and clinical trials for healthcare.
1+ YOEPhD in cell or molecular biology, 1-2 years lab experience with iPSC culture, sterile technique, directed differentiation; familiarity with Seahorse and 10X workflows; strong communication and organizational skills.
Sea horse, 10X Genomics, Chromium, Visium, Flow cytometry, FACS, Confocal microscopy
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Senior AI/ML Scientist, Planetary Science
Long Beach or New York City
$154k-$211k/yr HybridFull Time
Relativity Space
Relativity Space: Designing and manufacturing 3D-printed rockets and launch vehicles.
3+ YOEPhD in a technical field and 3+ years of experience; expertise in transfer learning, domain adaptation, or fine-tuning; multi-modal data fusion; end-to-end problem ownership; collaboration with scientists and engineers.
Python, TensorFlow, PyTorch, scikit-learn, ML frameworks, multi-modal data fusion
1d
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Senior Scientist, Discovery Biology
San Diego or Arizona or Puerto Rico or Los Angeles County
$132k-$159k/yr OnsiteFull Time
Bristol Myers Squibb
Bristol Myers SquibbNYSE: BMY: Develops and manufactures innovative prescription biopharmaceutical medicines.
2+ YOEBachelor's with 7+ years, master's with 5+ years, or Ph.D. with 2+ years in life sciences or related research. Requires cancer biology, cell culture, molecular biology, and drug discovery expertise.
CRISPR, RNAi, qPCR, FACS, Windows, Microsoft Office, PRISM
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Senior Data Scientist
New York or Austin or New York City or Los Angeles or San Francisco or London or Berlin or Singapore or Tel Aviv
HybridFull Time
Digital Turbine
Digital TurbineNASDAQ: APPS: Platform for mobile application distribution and advertising monetization.
8+ YOE8+ years in data science or quantitative analysis; expertise in experimental design, causal inference, statistical and ML modeling; SQL and Python or R; large-scale data; strong communication skills.
SQL, Python, R, Databricks, Spark
2d
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SENIOR DATA SCIENTIST
Los Angeles County or Los Angeles
$10k-$13k/mo HybridFull Time, Temporary
County of Los Angeles
County of Los Angeles: Provides public services and healthcare to Los Angeles County residents.
2+ YOE2+ MgmtRequires 2 years of complex data science experience, or a relevant bachelor's degree with coursework and 6 years of experience including 2 years leading machine learning, predictive analytics, and data management work.
Machine Learning, Predictive Analytics, Recommender Engines, Auto Classification, NLP, statistical programming languages
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Senior Data Scientist
Los Angeles, California, United States
$139k-$185k/yr HybridFull Time
Taboola
TaboolaNASDAQ: TBLA: Provides content recommendations and native advertising for digital publishers.
5+ YOEMaster’s degree or Ph.D. preferred in a technical field, 5+ years of Python and Java experience, ML frameworks, SQL, scalable ML systems, evaluation harnesses, testing frameworks, and distributed data systems.
Python, Java, PyTorch, TensorFlow, Spark MLlib, SQL, Cursor, Claude, GitHub Copilot, HDFS, Hadoop, Kafka, Apache Spark
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Senior Data Scientist
Irvine, California, United States
$108k-$153k/yr OnsiteFull Time
Edwards Lifesciences
Edwards LifesciencesNYSE: EW: Designs and manufactures medical devices for structural heart disease.
4+ YOEBachelor's in a related field plus 4 years (or Master’s plus 3) experience; expertise in clinical/product domain modeling, statistical methods, and regulatory-grade model documentation.
statsmodels, lifelines, scikit-survival, PyMC, SHAP, Captum, Python, SQL, SAS, Microsoft Power BI, Tableau Prep, PyTorch, TensorFlow, MLflow, MONAI, pydicom, SimpleITK, DoWhy, EconML, Optuna, Ray Tune, R, JAX
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Senior Data Scientist
Canada or United States or San Francisco or Los Angeles
$170k-$200k/yr RemoteFull Time
Northbeam
Northbeam: Marketing intelligence and attribution platform for eCommerce brands.
5+ YOE5+ years building and deploying production data science/ML systems; strong statistics, causal inference, experimentation, coding/debugging, EM/production ops, and customer-facing communication; BS required, MS/PhD preferred.
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Senior Data Scientist
Los Angeles, California, United States
$167k-$251k/yr HybridFull Time
Sony Interactive Entertainment
Sony Interactive EntertainmentTokyo Stock Exchange: 6758: Develops and publishes PlayStation gaming hardware, software, and services.
Requires proven analytical modeling experience, optimization or operations research knowledge, causal inference, end-to-end project ownership, large-dataset expertise, stakeholder communication, Python, SQL, and a quantitative master's or PhD.
Python, SQL, PySpark
2w
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Senior Data Scientist
Los Angeles, California, United States
$185k/yr OnsiteFull Time
FlightStory
FlightStory: A media and investment scaling creator-led brands.
Production ML/statistical modeling experience, strong Python and data science library skills, experience with large datasets and complex pipelines, and hands-on LLM or foundation model experience.
Python, PyTorch, TensorFlow, scikit-learn, LLMs, RAG