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4,173 senior software engineer python jobs at 1,123 companies in California

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
3mo
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Senior Software Engineer - Python
San Jose or Austin
$144k-$213k/yr HybridFull Time
PayPal
PayPalNASDAQ: PYPL: Digital platform for sending money and processing online payments.
3+ YOE3+ years Python backend experience; Bachelor's degree or equivalent; Django/Flask; SOA; REST/Web services; Git; cloud familiarity; SQL/NoSQL; CI/CD; distributed systems.
Python, Django, Flask, Git, AWS, GCP, Azure, Terraform, SQL, NoSQL, Redis, SQS, Kafka, CI/CD, Observability
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2mo
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Senior Software Engineer
Arlington or San Diego or Woburn
$139k-$180k/yr HybridFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
5+ YOESenior software engineer with strong C++, Python/MATLAB, RT real-time systems, security clearance eligibility.
C++, Python, MATLAB, CI/CD, Windows, Linux
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2mo
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Senior Software Engineer
San Francisco, California, United States
$180k-$215k/yr OnsiteFull Time
HeartFlow
HeartFlowNASDAQ: HTFL: Provides AI-driven non-invasive cardiac diagnostic software and analysis.
3+ YOESenior Software Engineer with strong Python, AWS, Django/JS, TypeScript, CI/CD, and experience building cloud-native APIs and web applications in regulated environments.
Python, AWS, Django, JavaScript, TypeScript, Nginx, Pytest, GitHub, GitHub Actions, Kubernetes, CDK, Step Functions, Lambdas, API Gateway, Fargate, ECS, Aurora
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1mo
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Senior Professional Software Engineer (Python)
Irvine or Oklahoma City or Sunrise or Oxford or Dallas or Austin
$129k-$165k/yr HybridFull Time
Cotality
Cotality: Provider of property intelligence, data, and analytics solutions.
5+ YOEBachelor's or Master's in Computer Science/AI or related, 5+ years software engineering, expert Python/FastAPI, microservices, Snowflake/Databricks, cloud (GCP/AWS/Azure), Agile (Jira/Confluence), strong communication and mentoring skills.
Python, FastAPI, Snowflake, Databricks, GCP, AWS, Azure, Jira, Confluence, YAML
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1mo
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Senior Software Engineer
Sunnyvale, California, United States
$160k-$185k/yr OnsiteFull Time
LTA Research & Exploration
LTA Research & Exploration: Develops and builds next-generation zero-emission rigid airships.
7+ YOE7-5 years of experience in a similar Senior Software Engineer role; proficient in RTOS, embedded systems, C#, C++, Python; GitLab CI/CD; strong communication.
C#, C++, RTOS, Python, Scripting, GitLab CI/CD
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2mo
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Senior Software Engineer, AI
El Segundo or United States
$153k-$170k/yr RemoteFull Time
ImmunityBio
ImmunityBioNASDAQ: IBRX: Develops next-generation immunotherapies for cancer and infectious diseases.
7+ YOESenior software engineer with 7+ years of experience in Python/Typescript, AI agent frameworks, and production-grade systems.
Python, TypeScript, FastAPI, Docker, LangGraph, LangChain, CrewAI, LlamaIndex, Chroma, Milvus, Weaviate, Qdrant
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2mo
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Senior Software Engineer
San Francisco, California, United States
HybridFull Time
Scope
Scope: Building custom AI systems and agents for enterprise workflows.
6+ YOESenior software engineer with 6+ years of production experience across frontend and backend; proficient in Python, TypeScript, React/Next.js; Docker/Kubernetes on cloud; CI/CD; and LLM frameworks.
Python, TypeScript, React, Next.js, Docker, Kubernetes, Terraform, CI/CD, LangChain, LangGraph, Anthropic SDK, OpenAI SDK, MCP, GCP, AWS
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1mo
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Senior Professional Software Engineer (Python)
Irvine or Oklahoma City or Sunrise or Oxford or Dallas or Austin or United States
$129k-$165k/yr HybridFull Time
Cotality
Cotality: Provides property data, analytics, and workflow intelligence solutions.
5+ YOEBachelor's degree in CS/AI (or related), 5+ years software engineering, expert Python/FastAPI, microservices and API design, Snowflake/Databricks experience, cloud (GCP/AWS/Azure), Agile (Jira/Confluence), TDD, UI/UX and ontology/semantic knowledge.
Python, FastAPI, Snowflake, Databricks, GCP, AWS, Azure, Jira, Confluence, YAML
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Senior Software Engineer (Python), Mortgage
San Francisco, California, United States
$185k-$218k/yr HybridFull Time
Checkr
Checkr: AI-powered platform for background checks and identity verification.
5+ YOE5+ years software development experience, proficiency in Python and Javascript, RESTful API development, bachelor's or equivalent, strong communication, ownership, and product focus.
Python, Javascript, RESTful APIs
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2mo
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Senior Systems Software Engineer
Sunnyvale, California, United States
$137k-$277k/yr OnsiteFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Providing global edge-to-cloud infrastructure and IT solutions for businesses.
6+ YOESenior software engineering role focused on systems software, with 6+ years in networking protocols, Python automation, and test experience.
Python, Robot Framework, JIRA, Spirent, IXIA, Kubernetes
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2mo
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Senior Staff, Software Engineer
Palo Alto or United States
$185k-$260k/yr HybridFull Time
DELFI Diagnostics
DELFI Diagnostics: Developing blood-based tests for early cancer detection.
10+ YOESenior-level software engineer with cloud, Python and a compiled language, life sciences exposure, and leadership experience.
Python, Rust, Java, C++, C#, AWS, Jira, Git, CI/CD
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3mo
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Senior Software Engineer
San Carlos, California, United States
$141k-$218k/yr OnsiteFull Time
Joby Aviation
Joby AviationNYSE: JOBY: Manufacturer of electric vertical takeoff and landing aircraft.
5+ YOE5+ years software engineering; advanced Python; Docker; RESTful APIs; event-driven architecture (Kafka).
Python, Docker, REST API, Kafka
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1mo
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Senior Software Engineer
San Francisco or Mountain View or Sunnyvale
$125k-$234k/yr HybridFull Time
General Motors
General MotorsNYSE: GM: Manufactures and sells automobiles and automotive parts globally.
4+ YOESenior software engineer with 4+ years in Linux C++, ROS, and embedded systems; strong design, CI, testing, and collaboration skills.
C++, Python, ROS, Bazel, CMake, Linux, POSIX, SOME/IP, ARXML, Networking
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2w
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Senior Software Engineer - LabView And Python
Cupertino, California, United States
$90k-$160k/yr OnsiteFull Time
Tata Consultancy Services
Tata Consultancy ServicesNational Stock Exchange of India: TCS: Global provider of IT services, consulting, and business solutions.
8+ YOE8+ years experience building DAQ and test software with LabVIEW and Python; proficiency with Unix, Git/SVN, DAQ hardware, and hardware validation.
LabVIEW, Python, Unix, Git, SVN, NI TestStand, C, C++, Radar, Data acquisition (DAQ), Automated Test Equipment (ATE), CI/CD
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2mo
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Senior Software Engineer, Developer Experience
Bellevue or Livingston or New York or San Francisco or Sunnyvale
$165k-$242k/yr HybridFull Time
CoreWeave
CoreWeaveNASDAQ: CRWV: Cloud platform providing GPU-accelerated infrastructure for AI workloads.
7+ YOESenior software engineer with 7+ years in production platforms, distributed systems, and developer tooling.
Go, Python, Kubernetes, GitHub Actions, Buildkite, Bazel, Artifactory, MCP
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2mo
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Senior Software Engineer, Perception
Costa Mesa, California, United States
$220k-$292k/yr OnsiteFull Time
Anduril Industries
Anduril Industries: Defense technology building autonomous military hardware and software.
4+ YOESenior software engineer for computer vision and ML in Linux; strong C++/Python, ML models, CV/robotics focus, security clearance eligible.
C++, Python, Linux, TensorRT, ONNX, PyTorch, TensorFlow, CI/CD
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1mo
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Senior Software Engineer
Menlo Park, California, United States
$214k-$245k/yr HybridFull Time
Robinhood
RobinhoodNASDAQ: HOOD: Provides a commission-free platform for investing and financial services.
5+ YOE5+ years of software engineering; proficient in Java, Kotlin, Go, Python, or Scala; backend services; REST APIs; databases; distributed systems; testing; background checks.
Java, Kotlin, GoLang, Python, Scala, Backend service frameworks, RESTful APIs, PostgreSQL, MySQL, Redis, DynamoDB, Distributed systems, Logging and monitoring tools, Automated testing frameworks
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1mo
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Senior Software Engineer
Los Angeles, California, United States
$180k-$200k/yr OnsiteFull Time
Motorola Solutions
Motorola SolutionsNYSE: MSI: Provides mission-critical communications and public safety technology.
8+ YOE8+ years software engineering; 6+ years Python/NodeJS; Linux/DevOps; Docker/Kubernetes; Jira/Azure DevOps; US citizen with ability to obtain security clearance.
Python, Node.js, Linux, DevOps, Docker, Kubernetes, Jira, Azure DevOps
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1mo
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
Tyba
Tyba: AI software for modeling and operating renewable energy projects.
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
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2mo
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Senior Software Engineer
Boston or Chicago or Dallas or San Francisco
$120k-$150k/yr OnsiteFull Time
JLL
JLLNYSE: JLL: Global commercial real estate and investment management services.
7+ YOE7+ years in full stack software engineering; Python and Node.js; API/microservices experience; front-end frameworks; cloud (Azure/AWS/GCP); AI/RAG knowledge a plus; CI/CD and testing.
Python, Node.js, React, Angular, Docker, Kubernetes, Git, GitHub, Azure DevOps, SQL Server, CosmosDB
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