89 senior software engineer python jobs at 22 companies in Danville, VA
🚀PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yrOn-SiteFull Time
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
Santa Clara or Austin or Westford or Durham or Seattle
$224k-$431k/yrOnsiteFull Time
NVIDIANASDAQ: NVDA: Designs graphics processing units and artificial intelligence hardware.
12+ YOE12+ years software engineering experience with GPU computing or ML systems, strong Python or C++ skills, GPU kernel optimization (CUDA/Triton), container engineering, and LLM inference knowledge.
5+ YOEBachelor's or equivalent experience; 5+ years programming in C++, Go, or Python; 3+ years developing large-scale infrastructure/distributed systems; 3+ years with Kubernetes and IaaS; 3+ years testing/maintaining software and 2+ years software design/architecture.
C++, Go, Python, Kubernetes, IaaS, Cloud Functions, Golang, Open Network Technology for Appliance Products (ONTAP's), Storage Virtual Machines (SVMs), Role-Based Access Control (RBAC), Root-Cause/Remediation (RCR)
San Jose or Durham or Mexico City or Vancouver or Bengaluru or Pune or Hoofddorp or Belgrade or Barcelona or Singapore or Sydney or Tokyo
$171k-$257k/yrHybridFull Time
NutanixNASDAQ: NTNX: Sells cloud software and hyperconverged infrastructure for enterprises.
8+ YOE8+ years building distributed, high-performance systems; strong Go/Python, Docker, Kubernetes, CI/CD; knowledge of datacenter, OS internals, virtualization, and ML frameworks.
Poughkeepsie or Lowell or Rochester or Tucson or Research Triangle Park or Armonk or Durham or Raleigh or Boston or Bellevue or Atlanta or San Jose or Dallas or Austin or San Francisco or Seattle
$131k-$245k/yrRemoteFull Time
IBMNew York Stock Exchange: IBM: Global technology providing enterprise software, cloud, and consulting.
5+ YOEBS/MS/PhD in CS or related (or equivalent experience), 5+ years building and operating cloud services or large-scale distributed systems; proficiency with Java or Go and Python; experience with CI/CD, containers, infra-as-code; on-call/incident response experience.
CiscoNASDAQ: CSCO: Develops and sells networking hardware and cybersecurity software.
8+ YOEBachelor's or equivalent, 8+ years software engineering experience, 5+ years distributed systems, proficiency in Go/Python/Java, REST, cloud and Kubernetes experience, CI/CD and observability, experience with LLM/RAG pipelines preferred.
Forterra: Develops autonomous ground vehicle systems and software for defense.
3+ YOE3+ years embedded/edge software experience, strong modern C++ (C++17/20) on Linux, Python for tooling, experience with real-time low-latency systems, Protobuf/data formats, CMake/Conan/Docker, and hardware bring-up.
Retired.com: Self-directed retirement platform for alternative asset investments.
7+ YOE2+ Mgmt7+ years software development; 2+ years leading teams; strong cloud-native, scalable architecture; Agile/CI/CD; bachelor's in CS/Software Eng or related experience.
Menlo Park or Sunnyvale or Durham or Washington or United Kingdom
$169k-$224k/yrHybridFull Time
GRAILNasdaq: GRAL: Develops blood tests for early-stage multi-cancer detection.
8+ YOE8+ years building full‑stack and distributed systems; proficiency with Go/Java/Python/JS, cloud platforms, Kubernetes, microservices, databases; BS/MS in CS or equivalent experience.
Principal Software Engineer - Variant Knowledge Platform
Durham or United States
$180k-$205k/yrHybridFull Time
LabcorpNYSE: LH: Provides clinical laboratory testing and drug development services globally.
5+ YOEBachelor's degree; 5+ years REST API and backend development (e.g., Python); 2+ years designing/operating AWS cloud services; experience with API versioning, Okta-based authentication, data modeling, observability, and large-scale data migrations.
Digital TurbineNASDAQ: APPS: Platform for mobile application distribution and advertising monetization.
8+ YOE8+ years building production platforms with strong backend architecture, algorithmic fundamentals, multi-language proficiency (e.g., TypeScript, Java, Python, Go, C++), front-end framework experience (React), and working knowledge of relational/distributed data stores.
MACOMNASDAQ: MTSI: Designs and manufactures semiconductor products for communications infrastructure.
5+ YOEBachelor’s or Master’s in CS/AI/DS; 5-10 years AI/ML engineering; Python and ML frameworks; agentic AI; cloud-based architectures; collaboration across teams.
NubankNYSE: NU: Digital financial platform offering banking, credit, and investment services.
Proven experience shipping LLM-powered systems in production; strong prompt/context engineering, evaluation and guardrail development, and software engineering skills (Python/TypeScript/Clojure).
Python, TypeScript, Clojure, n8n, Zapier, AWS, Claude Code, Cursor, Copilot, Slack, Google Workspace, Jira, Terraform, RAG, MCP
Berlin or Boston or Durham or Munich or London or Valencia
HybridFull Time
commercetools: SaaS platform for building enterprise headless commerce experiences.
5+ YOE5+ years shipping production software, 2+ years building with LLMs; full-stack ownership; experience with agents, prompt engineering, retrieval/embeddings, SQL, Python, TypeScript/Node and React.
Senior Platform Engineer, Data & AI Infrastructure
Durham or New York City or Los Angeles or Phoenix
$140k-$160k/yrHybridFull Time
McKinney: Provides strategic advertising and creative marketing services to brands.
4+ YOE4+ years of professional software engineering with backend focus; strong Python, cloud, and data tooling; experience with AI/LLM integration and security best practices.