67 applied research scientist jobs at 33 companies in Massachusetts
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Senior Applied Scientist
North Reading, Massachusetts, United States
$167k-$226k/yrOnsiteFull Time
AmazonNASDAQ: AMZN: Multinational technology focused on e-commerce and cloud computing.
3+ YOERequires 3+ years building machine learning models, PhD or master's degree plus 6+ years applied research, programming, deep learning, control, simulation, and real-time controller experience.
Senior Applied Research Scientist – Computational Geometry and Meshing
California or Westford or New York or Washington or Pennsylvania
$192k-$357k/yrRemoteFull Time
NVIDIANASDAQ: NVDA: Computing platform for AI and accelerated graphics.
5+ YOEPhD or equivalent experience in a relevant technical field, 5+ years in computational engineering, and C++ and Python skills with computational geometry, meshing, discretization, and simulation expertise.
Senior Applied Research Scientist – GPU Native Numerical Algorithms
California or New York or Massachusetts or Pennsylvania
$192k-$357k/yrRemoteFull Time
NVIDIANASDAQ: NVDA: Computing platform for AI and accelerated graphics.
5+ YOEPhD or equivalent experience, 5+ years in computational science, numerical methods, or HPC, and experience with C++, Python, CUDA/GPU code, numerical software, and GPU performance analysis.
Senior Applied Research Scientist – GPU Native Numerical Algorithms
California or New York or Pennsylvania or Massachusetts
$192k-$357k/yrRemoteFull Time
NVIDIANASDAQ: NVDA: Computing platform for AI and accelerated graphics.
5+ YOEPhD or equivalent experience and 5+ years in computational science, numerical methods, or HPC; requires C++/Python, CUDA or GPU code, PDE methods, solver development, and GPU performance analysis.
Alabama or Arizona or California or Colorado or District of Columbia or Florida or Georgia or Hawaii or Illinois or Indiana or Kansas or Massachusetts or Maryland or Michigan or Minnesota or Missouri or Montana or North Carolina or New Jersey or New Mexico or Nevada or New York or Ohio or Oklahoma or Oregon or Rhode Island or Tennessee or Texas or Utah or Virginia or Washington or Wisconsin or West Virginia or United Kingdom
$120k-$170k/yrRemoteFull Time
Slingshot Aerospace: Private aerospace software helping government and commercial operators track, model, and coordinate space activity.
2+ YOEActive U.S. security clearance (Secret minimum), Masters (or PhD) in related field, 2+ years' relevant experience (or PhD research), AI/ML expertise, software development skills, strong communication, ability to work with multidisciplinary teams.
XPONYSE: XPO: Provider of less-than-truckload (LTL) freight transportation and logistics.
1+ YOEBachelor's degree or equivalent experience, 1+ year designing model evaluation benchmarks, applied AI systems experience, Python and modern ML/AI frameworks, and strong stakeholder communication skills.
United States or Berlin or Boston or Cologne or Karlsruhe or London or Munich or San Francisco or Zurich
HybridFull Time, Part Time
QuantCo: Privately held data-science and AI engineering helping enterprises and public-sector organizations make decisions.
Expertise in machine learning, statistics, econometrics, or causal inference; strong mathematical and statistical foundations; Python and ML ecosystem fluency; and a quantitative degree. Advanced degree and foundation-model experience preferred.
Staff Applied Scientist (Distribution Center Solutions)
Alabama or Arkansas or California or Colorado or Florida or Georgia or Illinois or Kentucky or Massachusetts or Michigan or Montana or Missouri or Nevada or New Jersey or New York or North Carolina or Oregon or Pennsylvania or Texas or Washington or Utah or Virginia or Wisconsin or Ontario
$169k-$252k/yrRemoteFull Time
Afresh: Private AI software helping grocery retailers order, manage, and sell food with less waste.
4+ YOEMS/PhD in a quantitative field (or equivalent experience), 4+ years industry experience (PhD) / 8+ years (MS), expertise in ML/forecasting/operations research/stochastic optimization, ability to implement scalable Python data-stack solutions.
Python, numpy, torch, pandas, Electronic Medical Records (EMR)
RokuNASDAQ: ROKU: TV streaming platform powering the global television ecosystem.
10+ YOEPhD-preferred research data scientist with 10+ years applying causal inference and ML to large observational datasets; expertise in observational causal methods, communication skills, and productionizing pipelines.
Anduril Industries: Defense technology developing AI-powered autonomous military systems.
M.S. or Ph.D. in a quantitative field; strong background in applied math, controls, estimation, scientific computing, probability; ability to prototype algorithms and implement high-performance software; strong communication skills; eligible for Top Secret/SCI.
Applied Hypersonics Research Principal Scientist/Engineer
Andover, Massachusetts, United States
$118k-$140k/yrOnsiteFull Time
Protection Strategies Inc.: Employee-owned contract R&D serving government and commercial customers across defense, healthcare, energy, and industrial markets.
Advanced degree or equivalent experience in chemistry, physics, or applied engineering; extensive experimental and data analysis experience; technical leadership; peer-reviewed publications; excellent written and oral English; U.S. citizenship.
SLBNYSE: SLB: Global technology driving energy innovation.
2+ YOERequires an MSc or PhD in geosciences, petroleum engineering, applied physics, or related field; 2+ years of geosciences research or technical experience; simulation tools; scientific computing; and Python, C/C++, Fortran, or MATLAB.
PfizerNYSE: PFE: Multinational pharmaceutical and biotechnology.
2+ YOEPhD in a relevant biological or biomedical discipline, 2+ years applying fluorescence or confocal microscopy, and experience developing imaging assays, analyzing data, programming, and supporting flow cytometry.
Applied Scientist, AI & Deep Learning (mid to senior level)
Cambridge, Massachusetts, United States
$120k-$220k/yrHybridFull Time
Charles River Analytics: Private R&D developing human-centered AI, robotics, and autonomous systems for government and commercial customers.
3+ YOEU.S. citizen able to obtain security clearance, Bachelors in CS or related field required, 3+ years building ML/AI systems (or graduate degree), Python and Linux proficiency, strong math and communication skills.
Systems & Technology Research: Advanced research and development for national security and defense.
8+ YOEMS with 8+ years or PhD with 5+ years in applied math, physics, electrical engineering, CS, or data science; ML/AI expertise; PyTorch/TensorFlow/JAX; data science tools; Python/C/C++; ability to lead teams and obtain security clearance.
Riverlane: Quantum computing building real-time error-correction software and hardware for computer makers, governments, and research labs.
PhD required with research experience in quantum computing; experience designing/running/analyzing experiments or simulations; strong written/verbal communication; customer collaboration; willingness to travel US/UK.
Sr. Scientist I/Sr. Scientist II, Applied AI & Agentic Systems for Drug Discovery
Boston or San Francisco
$160k-$220k/yrHybridFull Time
Antares Therapeutics: Private biotechnology developing first-in-class precision medicines for cancer and other serious diseases.
5+ YOEPhD or equivalent in a quantitative field, 5+ years relevant experience for Scientist I or 8+ for Scientist II, drug discovery contributions, LLM agent development, Python, MLOps, and scientific communication.
Large Language Models (LLM), Model Context Protocol (MCP), LIMS, ELN, MLOps, Python, Claude, GPT, Claude Code, Codex, RDKit, OpenEye, Schrödinger
Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery
Boston, Massachusetts, United States
$168k-$252k/yrHybridFull Time
Vertex PharmaceuticalsNASDAQ: VRTX: Global biotechnology investing in scientific innovation.
8+ YOEPh.D. in a relevant scientific discipline and 8+ years applying computational chemistry, cheminformatics, or related approaches to small-molecule drug discovery; expertise in AI-enabled research and cross-functional leadership required.
AI, agentic systems, large language models, retrieval-augmented workflows, computational chemistry, cheminformatics, machine learning, scientific data science
Principal Scientist / Associate Director, Agentic AI Research for Materials Science
Cambridge or San Francisco
$288k-$420k/yrOnsiteFull Time
Lila Sciences: Builds AI and autonomous labs for scientific discovery.
5+ YOEPhD with 5+ years post-PhD research and applied ML experience; track record building agentic systems; expertise in LLMs, reasoning, multimodal data, materials science grounding; Python proficiency; leadership and communication skills.