60 applied research scientist jobs at 30 companies in Worcester, MA

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Senior Applied Scientist
North Reading, Massachusetts, United States
$167k-$226k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Multinational technology focused on e-commerce and cloud computing.
3+ YOERequires 3+ years building machine learning models, PhD or master's degree plus 6+ years applied research, programming, deep learning, control, simulation, and real-time controller experience.
Java, C++, Python, IsaacLab, MuJoCo, Drake, R, scikit-learn, Apache Spark, MXNet, TensorFlow, NumPy, SciPy, Hadoop, MATLAB, ROS
1w
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Senior Applied Research Scientist – Computational Geometry and Meshing
California or Westford or New York or Washington or Pennsylvania
$192k-$357k/yr RemoteFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Computing platform for AI and accelerated graphics.
5+ YOEPhD or equivalent experience in a relevant technical field, 5+ years in computational engineering, and C++ and Python skills with computational geometry, meshing, discretization, and simulation expertise.
C++, Python, Parasolid, ACIS, Open Cascade, CATIA, NX, Creo, SOLIDWORKS, STEP, IGES, B-Rep, NURBS, Omniverse, OpenUSD, Warp
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Applied AI Scientist - Hybrid
Boston, Massachusetts, United States
$100k-$120k/yr HybridFull Time
XPO
XPONYSE: XPO: Provides less-than-truckload freight transportation and logistics services.
1+ YOEBachelor's degree or equivalent experience, 1+ year designing model evaluation benchmarks, applied AI systems experience, Python and modern ML/AI frameworks, and strong stakeholder communication skills.
Python, PyTorch, HuggingFace, Chronos, RLHF, RAG
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Senior Research Data Scientist
Boston or New York
$330k-$375k/yr HybridFull Time
Roku
RokuNASDAQ: ROKU: TV streaming platform powering the global television ecosystem.
10+ YOEPhD-preferred research data scientist with 10+ years applying causal inference and ML to large observational datasets; expertise in observational causal methods, communication skills, and productionizing pipelines.
Spark, Ray, SQL, Python, scikit-learn, XGBoost, LightGBM
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AI Research Scientist
Bethesda or Cambridge
OnsiteFull Time
Netrias
Netrias: Private U.S. AI software that harmonizes life-sciences data for biopharma and research customers.
Experience developing AI models, identifying and fixing model failures, and applying curiosity to advance machine learning state of the art.
1mo
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Research Scientist, Battlespace Awarenss
Waltham, Massachusetts, United States
$191k-$253k/yr OnsiteFull Time
Anduril Industries
Anduril Industries: Defense technology developing AI-powered autonomous military systems.
M.S. or Ph.D. in a quantitative field; strong background in applied math, controls, estimation, scientific computing, probability; ability to prototype algorithms and implement high-performance software; strong communication skills; eligible for Top Secret/SCI.
Lattice OS
4w
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Applied Hypersonics Research Principal Scientist/Engineer
Andover, Massachusetts, United States
$118k-$140k/yr OnsiteFull Time
Protection Strategies Inc.
Protection Strategies Inc.: Employee-owned contract R&D serving government and commercial customers across defense, healthcare, energy, and industrial markets.
Advanced degree or equivalent experience in chemistry, physics, or applied engineering; extensive experimental and data analysis experience; technical leadership; peer-reviewed publications; excellent written and oral English; U.S. citizenship.
Schlieren, Pitot, PLIF, IR, UV, laser absorption, emission spectroscopy, vacuum systems, plasma technologies
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Modeling & Simulation Research Scientist
Cambridge or United States
$105k-$214k/yr OnsiteFull Time
SLB
SLBNYSE: SLB: Global technology driving energy innovation.
2+ YOERequires an MSc or PhD in geosciences, petroleum engineering, applied physics, or related field; 2+ years of geosciences research or technical experience; simulation tools; scientific computing; and Python, C/C++, Fortran, or MATLAB.
Python, C, C++, Fortran, MATLAB, Intersect, Visage, Petrel
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Senior Research Scientist, High Content Imaging
Groton or Cambridge or United States
$94k-$156k/yr OnsiteFull Time
Pfizer
PfizerNYSE: PFE: Develops and manufactures vaccines and medicines for global healthcare
2+ YOEPhD in a relevant biological or biomedical discipline, 2+ years applying fluorescence or confocal microscopy, and experience developing imaging assays, analyzing data, programming, and supporting flow cytometry.
high-content imaging, flow cytometry, fluorescence microscopy, confocal microscopy, image-analysis software, plate-based imaging systems, flow cytometry instrumentation, scripting, programming, automated systems
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Applied Scientist, AI & Deep Learning (mid to senior level)
Cambridge, Massachusetts, United States
$120k-$220k/yr HybridFull Time
Charles River Analytics
Charles River Analytics: Private R&D developing human-centered AI, robotics, and autonomous systems for government and commercial customers.
3+ YOEU.S. citizen able to obtain security clearance, Bachelors in CS or related field required, 3+ years building ML/AI systems (or graduate degree), Python and Linux proficiency, strong math and communication skills.
Python, Linux
3mo
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Lead Research Scientist - Machine Learning
Woburn, Massachusetts, United States
$174k-$220k/yr OnsiteFull Time
Systems & Technology Research
Systems & Technology Research: Advanced research and development for national security and defense.
8+ YOEMS with 8+ years or PhD with 5+ years in applied math, physics, electrical engineering, CS, or data science; ML/AI expertise; PyTorch/TensorFlow/JAX; data science tools; Python/C/C++; ability to lead teams and obtain security clearance.
PyTorch, JAX, TensorFlow, scikit-learn, Pandas, Matplotlib, Python, C/C++
2mo
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Quantum Scientist - Applied QEC
Boston, Massachusetts, United States
$135k-$170k/yr HybridFull Time
Riverlane
Riverlane: Quantum computing building real-time error-correction software and hardware for computer makers, governments, and research labs.
PhD required with research experience in quantum computing; experience designing/running/analyzing experiments or simulations; strong written/verbal communication; customer collaboration; willingness to travel US/UK.
DeltaKit Software, Deltaflow
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Sr. Scientist I/Sr. Scientist II, Applied AI & Agentic Systems for Drug Discovery
Boston or San Francisco
$160k-$220k/yr HybridFull Time
Antares Therapeutics
Antares Therapeutics: Private biotechnology developing first-in-class precision medicines for cancer and other serious diseases.
5+ YOEPhD or equivalent in a quantitative field, 5+ years relevant experience for Scientist I or 8+ for Scientist II, drug discovery contributions, LLM agent development, Python, MLOps, and scientific communication.
Large Language Models (LLM), Model Context Protocol (MCP), LIMS, ELN, MLOps, Python, Claude, GPT, Claude Code, Codex, RDKit, OpenEye, Schrödinger
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Principal Scientist / Associate Director, Agentic AI Research for Materials Science
Cambridge or San Francisco
$288k-$420k/yr OnsiteFull Time
Lila Sciences
Lila Sciences: Builds AI and autonomous labs for scientific discovery.
5+ YOEPhD with 5+ years post-PhD research and applied ML experience; track record building agentic systems; expertise in LLMs, reasoning, multimodal data, materials science grounding; Python proficiency; leadership and communication skills.
Python, LLMs, HPC
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Behavioral Scientist, Nudge Unit & Behavioral Insights
Boston, Massachusetts, United States
$90k-$110k/yr HybridFull Time
Blue Cross Blue Shield of Massachusetts
Blue Cross Blue Shield of Massachusetts: Provides health and dental insurance plans and managed care.
4+ YOEBachelor's degree in a related field and 4+ years of relevant experience in behavioral science, applied research, program evaluation, consulting, or a related field; research, evaluation, communication, and project coordination skills.
1mo
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AI Scientist – AI-Driven Target Identification
Cambridge or Basel
$104k-$192k/yr HybridFull Time
Novartis
NovartisNew York Stock Exchange: NVS: Develops and manufactures innovative prescription medicines for patients.
PhD required in ML, CS, applied math, computational biology or related; strong experience in generative AI, foundation models, geometric deep learning, multimodal learning, and knowledge graphs; proficient in PyTorch and Python; research publication record.
PyTorch, Python
1mo
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QSP postdoctoral scientist
Boston or Indianapolis
$58k-$123k/yr OnsiteFull Time
Eli Lilly and Company
Eli Lilly and CompanyNYSE: LLY: Researches and manufactures medicines for human health.
PhD in quantitative pharmacology/systems biology/applied math or related, experience with QSP/ODE models, virtual populations, parameter estimation; proficiency in R, Matlab/Simbiology, Python, NONMEM or Monolix; authorized to work in the US.
R, Matlab/Simbiology, Python, NONMEM, Monolix
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Senior Bioinformatics Scientist
Boston, Massachusetts, United States
OnsiteFull Time
Cellular Intelligence
Cellular Intelligence: AI-native clinical-stage TechBio building cell-signaling foundation models and developing regenerative cell therapies.
3+ YOEPhD or equivalent experience preferred,3+ years developing bioinformatics methods and pipelines for single-cell/spatial transcriptomics; strong Python and/or R skills; experience with Nextflow or Snakemake, containers, version control, and applying LLMs; mentorship experience.
Python, R, Nextflow, Snakemake, LLMs
2mo
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Applications Scientist 3
Hillsboro or Wilmington or Texas or United States
$97k-$145k/yr OnsiteFull Time
Onto Innovation
Onto InnovationNYSE: ONTO: Provides metrology and inspection solutions for semiconductor manufacturers.
0+ YOEDegree in physics, materials science, EE, applied math or related; 0-3 years experience; optics and metrology knowledge; scripting (Matlab/Python) and data analysis a plus; able to travel up to 20% and work in fabs up to 40%.
Matlab, Python
1mo
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Senior Scientist, Antibody Repertoire Sequencing & Discovery
Worcester, Massachusetts, United States
$110k-$209k/yr OnsiteFull Time
AbbVie
AbbVieNYSE: ABBV: Develops and sells innovative pharmaceutical and biopharmaceutical medicines.
Expertise in antibody repertoire sequencing and immunoglobulin genetics; proficiency with NGS platforms, molecular biology techniques, and antibody/DNA analysis software; experience applying computational/AI methods to antibody discovery.
PipeBio, Geneious, Sequencher, Microsoft Excel, Microsoft PowerPoint, Microsoft Word, Illumina NextSeq, Illumina MiSeq, PacBio