67 applied scientist jobs at 30 companies in Upton, MA

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Senior Applied Scientist
North Reading, Massachusetts, United States
$167k-$226k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Global online retail and cloud computing technology provider.
3+ YOERequires 3+ years building machine learning models, PhD or master's degree plus 6+ years applied research, programming, deep learning, control, simulation, and real-time controller experience.
Java, C++, Python, IsaacLab, MuJoCo, Drake, R, scikit-learn, Apache Spark, MXNet, TensorFlow, NumPy, SciPy, Hadoop, MATLAB, ROS
1mo
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Applied Scientist, AI & Deep Learning (mid to senior level)
Cambridge, Massachusetts, United States
$120k-$220k/yr HybridFull Time
Charles River Analytics
Charles River Analytics: Develops human-centered AI and intelligent systems for national security.
3+ YOEU.S. citizen able to obtain security clearance, Bachelors in CS or related field required, 3+ years building ML/AI systems (or graduate degree), Python and Linux proficiency, strong math and communication skills.
Python, Linux
1w
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Applied AI and Machine Learning Scientist (Director)
Cambridge, Massachusetts, United States
$177k-$294k/yr HybridFull Time
Pfizer
PfizerNYSE: PFE: Develops and manufactures vaccines and medicines for global healthcare
9+ YOEAdvanced degree preferred; ~9+ years relevant experience; demonstrated leadership in applied AI for drug discovery; strong knowledge of LLMs, foundation models, multimodal AI, and governance; ability to prioritize use cases and drive adoption.
LLMs, foundation models, agentic systems, multimodal AI, retrieval-augmented
2mo
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Quantum Scientist - Applied QEC
Boston, Massachusetts, United States
$135k-$170k/yr HybridFull Time
Riverlane
Riverlane: Develops quantum error correction software for fault-tolerant quantum computing.
PhD required with research experience in quantum computing; experience designing/running/analyzing experiments or simulations; strong written/verbal communication; customer collaboration; willingness to travel US/UK.
DeltaKit Software, Deltaflow
2mo
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Senior Scientist - Optical Signal Processing
Woburn or Arlington
$139k-$180k/yr OnsiteFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
3+ YOESenior scientist with 3-5+ years in physics/engineering; degree in physics, applied math, or electrical engineering; proficiency in MATLAB/Python/C/C++; security clearance eligibility; strong communication.
MATLAB, Python, C/C++
3w
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Senior Research Data Scientist
Boston or New York
$330k-$375k/yr HybridFull Time
Roku
RokuNASDAQ: ROKU: Operates a TV streaming platform and sells streaming hardware.
10+ YOEPhD-preferred research data scientist with 10+ years applying causal inference and ML to large observational datasets; expertise in observational causal methods, communication skills, and productionizing pipelines.
Spark, Ray, SQL, Python, scikit-learn, XGBoost, LightGBM
20h
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Staff Data Scientist
Westwood, Massachusetts, United States
$170k-$220k/yr HybridFull Time
The Predictive Index
The Predictive Index: Talent optimization platform providing behavioral assessments and workforce analytics.
7+ YOERequires 7+ years of staff-level product data science experience, product analytics and experimentation expertise, infrastructure-building experience, and a graduate degree or equivalent applied experience in a quantitative field.
AI
3w
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QSP postdoctoral scientist
Boston or Indianapolis
$58k-$123k/yr OnsiteFull Time
Eli Lilly and Company
Eli Lilly and CompanyNYSE: LLY: Researches and manufactures medicines for human health.
PhD in quantitative pharmacology/systems biology/applied math or related, experience with QSP/ODE models, virtual populations, parameter estimation; proficiency in R, Matlab/Simbiology, Python, NONMEM or Monolix; authorized to work in the US.
R, Matlab/Simbiology, Python, NONMEM, Monolix
3w
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Senior Bioinformatics Scientist
Boston, Massachusetts, United States
OnsiteFull Time
Cellular Intelligence
Cellular Intelligence: An AI-native TechBio building foundation models of cell signaling to advance regenerative medicine and therapeutic discovery.
3+ YOEPhD or equivalent experience preferred,3+ years developing bioinformatics methods and pipelines for single-cell/spatial transcriptomics; strong Python and/or R skills; experience with Nextflow or Snakemake, containers, version control, and applying LLMs; mentorship experience.
Python, R, Nextflow, Snakemake, LLMs
1mo
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Applications Scientist 3
Hillsboro or Wilmington or Texas or United States
$97k-$145k/yr OnsiteFull Time
Onto Innovation
Onto InnovationNYSE: ONTO: Provides metrology and inspection solutions for semiconductor manufacturers.
0+ YOEDegree in physics, materials science, EE, applied math or related; 0-3 years experience; optics and metrology knowledge; scripting (Matlab/Python) and data analysis a plus; able to travel up to 20% and work in fabs up to 40%.
Matlab, Python
2w
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Senior Scientist, Antibody Repertoire Sequencing & Discovery
Worcester, Massachusetts, United States
$110k-$209k/yr OnsiteFull Time
AbbVie
AbbVieNYSE: ABBV: Develops and sells innovative pharmaceutical and biopharmaceutical medicines.
Expertise in antibody repertoire sequencing and immunoglobulin genetics; proficiency with NGS platforms, molecular biology techniques, and antibody/DNA analysis software; experience applying computational/AI methods to antibody discovery.
PipeBio, Geneious, Sequencher, Microsoft Excel, Microsoft PowerPoint, Microsoft Word, Illumina NextSeq, Illumina MiSeq, PacBio
1w
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Data Scientist, Consultant (Utilities)
Boulder or New York City or Arlington or Austin or Chicago or Philadelphia or Atlanta or Boston
$89k-$148k/yr OnsiteFull Time
Guidehouse
Guidehouse: Provides management and technology consulting services to diverse organizations.
1+ YOEBachelor's degree and 1+ years applying data analytics; experience with Python, R, SQL, Databricks, Snowflake, Power BI, Tableau, or GIS; utility sector experience preferred.
Python, R, Snowflake, SQL, Databricks, Power BI, GIS, Tableau
1mo
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Associate Scientist/Sr. Associate Scientist/Scientist, Islet Process Sciences
Watertown, Massachusetts, United States
$115k-$150k/yr OnsiteFull Time
Century Therapeutics
Century TherapeuticsNASDAQ: IPSC: Develops engineered cell therapies for cancer and autoimmune diseases.
2+ YOEHands-on experience with human pluripotent stem cell culture and suspension bioreactors; ability to design and run differentiation experiments, analyze RT-qPCR/flow/ELISA data, apply DOE, and maintain high-quality documentation.
PBS Vertical Wheel bioreactors, RT-qPCR, Flow cytometry, ELISA, JMP, MODDE, GraphPad Prism, FlowJo, ImageJ/Fiji
3mo
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Staff Data Scientist
North Bethesda or Waltham
$163k-$190k/yr HybridFull Time
Xometry
XometryNASDAQ: XMTR: Operates an AI-powered marketplace for custom manufacturing and prototyping.
8+ YOE8+ years in data science/ML with a BA; 5-6+ years with a Master’s; PhD with 3-4+ years of applied experience; expert Python/SQL; experience with 3D geometry and AI in manufacturing.
Python, SQL, Geometric Deep Learning, 3D Computer Vision
1mo
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Research Scientist, Battlespace Awarenss
Waltham, Massachusetts, United States
$191k-$253k/yr OnsiteFull Time
Anduril Industries
Anduril Industries: Defense technology building autonomous military hardware and software.
M.S. or Ph.D. in a quantitative field; strong background in applied math, controls, estimation, scientific computing, probability; ability to prototype algorithms and implement high-performance software; strong communication skills; eligible for Top Secret/SCI.
Lattice OS
1w
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GCS, Data Scientist, AVP
Quincy, Massachusetts, United States
$90k-$158k/yr OnsiteFull Time
State Street
State StreetNYSE: STT: Provides investment servicing and management to institutional investors.
5+ YOE5+ years data science experience with 2+ years applying analytics to cybersecurity or similar enterprise datasets; Bachelor's in relevant field; hands-on Python, SQL, PySpark, Databricks, Power BI, AWS; strong communication and ML/graph/NLP experience.
Python, SQL, PySpark, Databricks, Power BI, AWS, SIEM, SOAR
1w
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Principal Scientist, Data Science
Titusville or Cambridge or Raritan or Spring House
$117k-$201k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Provides pharmaceutical products and medical technology healthcare solutions.
5+ YOEPhD in a quantitative discipline,5+ years applying ML/NLP/GenAI and optimization to real-world data (EHR/claims/registries),experience with multimodal RWD,stochastic simulation,optimization engines,Python and SQL proficiency,MLOps and data privacy familiarity.
MLflow, Kedro, Git, CI/CD, Python, SQL, DSPy, LangChain, pymoo, scikit learn, XGBoost, Optuna, PyMC
1mo
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Data Scientist, AI for Biomedical Imaging
Cambridge, Massachusetts, United States
$126k-$257k/yr OnsiteFull Time
Novartis
NovartisSIX Swiss Exchange, NYSE: NOVN, NVS: A global pharmaceutical conducting research and development to discover and develop medicines for patients.
3+ YOEPhD in a quantitative field with 3+ years applied AI for bioimaging; experience developing and validating image analysis algorithms, benchmarking methods, HPC/cloud workflows, and strong scientific communication.
Python, PyTorch, Hugging Face, Lightning, MONAI, scikit-image, OpenCV, napari, Cellpose, StarDist, InstanSeg, OME-Zarr, Linux, DINO, CLIP, SAM, Claude Code, Copilot
2w
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ML Data Scientist III ( Seattle/Provo)
Provo or Seattle or Chicago or Boston or South Bend
$100k-$140k/yr HybridFull Time
Press Ganey
Press Ganey: Provides patient experience measurement and healthcare performance analytics.
5+ YOEMaster's in CS/AI or related,5+ years in applied research or software engineering,proven conversational AI and generative AI experience,knowledge of ML/NLP and collaboration skills.
LangChain, LangGraph, MCP, ADK, A2A, Apache Spark, Databricks, Docker, Kubernetes, Azure, AWS, GCP
2w
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AI Scientist – Image Analysis & Digital Pathology
Cambridge, Massachusetts, United States
$126k-$234k/yr OnsiteFull Time
Novartis
NovartisNew York Stock Exchange: NVS: Develops and manufactures innovative prescription medicines for patients.
4+ YOEPhD in ML/CS/Applied Math/Computational Biology (or MS+4yrs), strong pathology imaging and ML experience, PyTorch/Python proficiency, publication record, and collaboration skills.
PyTorch, Python (Programming Language)