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77 computational biology jobs at 37 companies in Boston, MA

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Scientist, Computational Biology
Cambridge, Massachusetts, United States
$115k-$165k/yr OnsiteFull Time
Flagship Pioneering
Flagship Pioneering: Conceives, creates, and builds life science platform companies
2+ YOEPhD in computational biology or related field, 2+ years industry experience, strong mass-spec proteomics and multi-omics analysis, proficiency in R or Python, statistical and ML expertise, NGS experience.
R, Python, NGS, transformers, Greenhouse
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Principal Scientist, Computational Biology
Cambridge, Massachusetts, United States
$167k-$202k/yr OnsiteFull Time
Bristol Myers Squibb
Bristol Myers SquibbNYSE: BMY: Develops and manufactures innovative prescription biopharmaceutical medicines.
5+ YOEPhD in a quantitative field with 5+ years post-graduate experience; hands-on R or Python; experience with single-cell and multi-omics data, statistical and ML methods; strong communication and scientific curiosity.
R, Python, Claude
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Senior Scientist, Computational Biology - Contract
Somerville, Massachusetts, United States
$74-$80/hr OnsiteContract
Tessera Therapeutics
Tessera Therapeutics: Develops gene writing technology to treat and cure diseases.
5+ YOEPhD (5+ yrs) or MS (10+ yrs) or BS (12+ yrs); broad genome editing and off-target discovery knowledge; NGS data and QC; developing and troubleshooting NGS pipelines in cloud; Nextflow/Dagster; AWS, version control, and software development best practices.
Nextflow, Dagster, AWS, NGS, CI/CD, AI agents
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Principal Scientist, Computational Biology
Cambridge, Massachusetts, United States
$167k-$202k/yr OnsiteFull Time
Bristol Myers Squibb
Bristol Myers SquibbNew York Stock Exchange: BMY: Develops and distributes innovative medicines for serious diseases.
5+ YOEPhD in a quantitative field with 5+ years post‑graduate experience; advanced R or Python; experience with multi‑omics, single‑cell, spatial, and perturbation datasets; machine learning/statistical methods; strong communication.
R, Python, Claude
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Associate Director of Computational Biology & Bioinformatics
Boston, Massachusetts, United States
$200k-$240k/yr HybridFull Time
Institute for Protein Innovation
Institute for Protein Innovation: Develops and distributes recombinant protein tools for biomedical research.
5+ YOEPhD required; 5+ years relevant experience with team leadership; strong Python and PyTorch; experience developing protein ML models, multimodal biological data, de novo protein/antibody design; cloud/HPC and data portals preferred.
Python, PyTorch, OpenAntigens, LIMS, ELN, MLOps, APIs, GPU, Next Generation Sequencing (NGS), cloud computing, high-performance computing
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Computational Associate
Boston, Massachusetts, United States
$42k-$60k/yr OnsiteFull Time
Mass General Brigham: Provides integrated medical care, research, and clinical training services.
0+ YOEBachelor's degree in computational biology or a related quantitative field, 0–1 year experience, Python or R proficiency, and knowledge of computational modeling, statistics, machine learning, or biomedical data science.
Python, R, PyTorch, TensorFlow
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5d
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Computational Biologist I
Boston, Massachusetts, United States
$113k-$133k/yr HybridFull Time
Foundation Medicine
Foundation Medicine: Molecular profiling for personalized cancer treatment and research.
0+ YOEBachelor’s plus 6+ years, master’s plus 2+ years, or PhD with no experience; bioinformatics, cancer biology, NGS, programming, statistical analysis, DNA methylation, cloud computing, and data privacy knowledge.
Unix, Python, R, SQL, AWS, Git, TCGA, cBioPortal, Genomic Data Commons, HPC, NGS, DNA-seq, HIPAA
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Biology Teacher
Fall River, Massachusetts, United States
$59k-$105k/yr OnsiteFull Time
Fall River Public Schools
Fall River Public Schools: A public school district providing K-12 education in Massachusetts.
Appropriate Massachusetts educator licensure required; bachelor's in science preferred; basic computer skills; ability to teach high school biology and manage lab safety; participate in curriculum, professional development, and parent communication.
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Computational Scientist, Protein Engineering
Boston, Massachusetts, United States
$118k-$138k/yr OnsiteFull Time
Manifold Bio
Manifold Bio: Designing tissue-targeted protein therapeutics using AI and in vivo screening.
4+ YOEPhD and/or 4+ years in computational biology, bioinformatics, protein engineering, or related field; strong Python, data pipelines, Unix, and antibody engineering experience; experience with MPRA/NGS data; collaboration skills.
Python, Unix, Git, NGS data analysis
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Computational Scientist, Origin & Evolution of Life
Cambridge or London
OnsiteFull Time
Dayhoff Labs
Dayhoff Labs: AI-driven discovery for synthetic biology and chemical processes.
PhD and publication record in computational biology/chemistry/systems biology/chemical engineering or adjacent field; demonstrated independent research and cross-disciplinary breadth; ability to drive publication-quality research.
AI, ML, QM/MD
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Data Scientist Contractor, Computational Biology
Cambridge, Massachusetts, United States
OnsiteContract
CAMP4 Therapeutics
CAMP4 TherapeuticsNASDAQ: CAMP: Develops regulatory RNA-based therapeutics to treat genetic diseases.
3+ YOEPhD in bioinformatics/computational biology/systems biology, 3+ years industry or postdoc experience; strong RNA-seq, scRNA-seq, and long-read sequencing (Nanopore/PacBio) analysis; Python/R, Linux, HPC/AWS proficiency; reproducible research skills.
Python, R, Linux, AWS, Nanopore, PacBio, High-performance computing clusters, RAPTM Platform
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Computational Biologist, Tree of Life
Boston or London
OnsiteFull Time
Cultivarium
Cultivarium: Developing tools to engineer non-model microorganisms for research.
Master's in computational biology or related; authorized to work in the U.K.; experience with population- and comparative-genomics at population scale using tools like GATK, bcftools, vcftools, PLINK, ANGSD, scikit-allel; pipelines (Nextflow, Snakemake); Python/R, Biopython/Bioconductor/pandas, and Git; familiarity with organellar genomics.
GATK, bcftools, vcftools, PLINK, ANGSD, scikit-allel, Nextflow, Snakemake, Python, R, Biopython, Bioconductor, pandas, Git, ESM, Evo, Nucleotide Transformer, AWS, Google Cloud, Azure
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Biology Teacher (Long Term Sub)
Wareham, Massachusetts, United States
$323-$356/day OnsiteFull Time, Temporary
Wareham Public Schools
Wareham Public Schools: Operates public K-12 schools in Wareham, Massachusetts.
Massachusetts certification preferred; requires collaboration, strong communication, project management, grades 8–12 student experience, computing skills, and instructional equipment management.
computing technology
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Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)
South San Francisco or Cambridge or Thousand Oaks
$190k-$257k/yr HybridFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
4+ YOEPhD with 4+ yrs or MS with 7+ yrs or BS with 9+ yrs in computational biology/biomedical data; strong R/Python; cardiovascular/metabolic focus; matrixed environment experience.
R, Python, NGS, Mass Spectrometry, Proteomics, Transcriptomics, Metabolomics, Spatial Omics, Immunoassays, Flow Cytometry
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Senior / Principal Scientist, Structural Biology — Target Druggability & Structure-Based Drug Design
Framingham or New York City
$135k-$190k/yr OnsiteFull Time
Schrödinger
SchrödingerNASDAQ: SDGR: Computational platform for drug discovery and materials science.
PhD or equivalent experience; deep hands-on structure-based drug design expertise; computational structural biology fluency; and cryo-EM or X-ray crystallography experience.
Glide, FEP+, BioLuminate, Prime, AI/ML
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2mo
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Part-Time Lecturer (non-tenure track) for Bio 35 – Computational Biology
Medford, Massachusetts, United States
$12k/yr OnsitePart Time
Tufts University
Tufts University: Private research university offering undergraduate, graduate, and professional programs.
Ph.D. required with teaching experience in computational biology, bioinformatics, or related areas; ability to teach introductory Python and develop inclusive classroom materials; evidence of teaching success.
Python, Interfolio
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Postdoctoral AI Researcher in AI/ML for Cellular and Protein Computational Biology
Cambridge, Massachusetts, United States
$100k/yr OnsiteFull Time, Temporary
Harvard University
Harvard University: Private Ivy League research university providing higher education.
PhD in a quantitative field, modern AI/ML and deep learning expertise, Python programming, PyTorch or JAX experience, research publications, computational biology experience, and collaborative communication skills.
PyTorch, JAX, Python, Claude Code, Codex, AlphaFold, RFDiffusion, CellCap, Zoom
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Postdoctoral Research Fellow - Computational Biologist - Gillani Lab
Boston, Massachusetts, United States
$72k-$76k/yr OnsiteFull Time
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute: Provides comprehensive cancer treatment and conducts oncological research.
Ph.D. in related field required, significant computational biology research experience, proficiency in R and/or Python and cloud computing, strong statistics and biology background, excellent communication and teamwork.
R, Python, cloud computing
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Bioinformatics Senior Scientist-Biology
Cambridge, Massachusetts, United States
OnsiteFull Time
Zealand Pharma
Zealand PharmaNasdaq Copenhagen: ZEAL: Discovers and develops peptide-based medicines for metabolic and rare diseases.
4+ YOEPhD in bioinformatics/computational biology/genomics with postdoc experience (or MS+8yrs). 4+ years industry/translational experience, multi-omics analysis, pipeline development, reproducible workflows, ML/AI exposure, strong communication.
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Associate Scientist / Scientist I, Computational Test Development
Boston, Massachusetts, United States
$110k-$150k/yr HybridFull Time
Precede Biosciences
Precede Biosciences: Develops a blood-based epigenomics platform for precision medicine.
3+ YOEMSc in computational biology, bioinformatics, biostatistics, or related field; 3–4 years’ data-intensive biological research experience; R, Python, AWS, and NGS pipeline experience required. PhD preferred.
R, Python, AWS
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