80 computational biology jobs at 40 companies in Massachusetts
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Scientist, Computational Biology
Cambridge, Massachusetts, United States
$115k-$165k/yrOnsiteFull Time
Flagship Pioneering: Conceives, creates, and builds life science platform companies
2+ YOEPhD in computational biology or related field, 2+ years industry experience, strong mass-spec proteomics and multi-omics analysis, proficiency in R or Python, statistical and ML expertise, NGS experience.
Tessera Therapeutics: Develops gene writing technology to treat and cure diseases.
5+ YOEPhD (5+ yrs) or MS (10+ yrs) or BS (12+ yrs); broad genome editing and off-target discovery knowledge; NGS data and QC; developing and troubleshooting NGS pipelines in cloud; Nextflow/Dagster; AWS, version control, and software development best practices.
Bristol Myers SquibbNew York Stock Exchange: BMY: Develops and distributes innovative medicines for serious diseases.
5+ YOEPhD in a quantitative field with 5+ years post‑graduate experience; advanced R or Python; experience with multi‑omics, single‑cell, spatial, and perturbation datasets; machine learning/statistical methods; strong communication.
Associate Director of Computational Biology & Bioinformatics
Boston, Massachusetts, United States
$200k-$240k/yrHybridFull Time
Institute for Protein Innovation: Develops and distributes recombinant protein tools for biomedical research.
5+ YOEPhD required; 5+ years relevant experience with team leadership; strong Python and PyTorch; experience developing protein ML models, multimodal biological data, de novo protein/antibody design; cloud/HPC and data portals preferred.
Principal Computational Scientist - Discovery Biology N & I (Billerica MA)
Billerica, Massachusetts, United States
$140k-$210k/yrOnsiteFull Time
Merck KGaAFrankfurt Stock Exchange: MRK: Develops pharmaceutical, life science, and electronics technologies.
10+ YOEPhD in a quantitative or life science discipline with substantial computational biology specialization, significant postdoctoral or industry experience, pharma or biotech drug discovery experience, and strong Python or R skills.
Principal Computational Scientist - Discovery Biology N & I (Billerica MA)
Billerica, Massachusetts, United States
$140k-$210k/yrOnsiteFull Time
Merck KGaA, Darmstadt, GermanyFrankfurt Stock Exchange: MRK: A science and technology in healthcare, life sciences, and electronics.
10+ YOEPhD in a quantitative or life science field with computational biology specialization, significant postdoctoral or industry drug discovery experience, and expertise in functional genomics, multi-omics, Python or R, and predictive modeling.
Mass General Brigham: Provides integrated medical care, research, and clinical training services.
0+ YOEBachelor's degree in computational biology or a related quantitative field, 0–1 year experience, Python or R proficiency, and knowledge of computational modeling, statistics, machine learning, or biomedical data science.
Principal Computational Scientist - Discovery Biology N & I (Billerica MA)
Billerica, Massachusetts, United States
$140k-$210k/yrOnsiteFull Time
MerckXETRA: MRK: A science and technology providing healthcare, life science, and electronics solutions.
4+ YOEPhD in a quantitative or life-science discipline, significant postdoctoral or industry experience (pharma/biotech), expertise in computational biology/functional genomics, human genetics and multi-omics integration, strong programming in Python and/or R, and excellent communication.
Foundation Medicine: Molecular profiling for personalized cancer treatment and research.
0+ YOEBachelor’s plus 6+ years, master’s plus 2+ years, or PhD with no experience; bioinformatics, cancer biology, NGS, programming, statistical analysis, DNA methylation, cloud computing, and data privacy knowledge.
Fall River Public Schools: A public school district providing K-12 education in Massachusetts.
Appropriate Massachusetts educator licensure required; bachelor's in science preferred; basic computer skills; ability to teach high school biology and manage lab safety; participate in curriculum, professional development, and parent communication.
Manifold Bio: Designing tissue-targeted protein therapeutics using AI and in vivo screening.
4+ YOEPhD and/or 4+ years in computational biology, bioinformatics, protein engineering, or related field; strong Python, data pipelines, Unix, and antibody engineering experience; experience with MPRA/NGS data; collaboration skills.
Computational Scientist, Origin & Evolution of Life
Cambridge or London
OnsiteFull Time
Dayhoff Labs: AI-driven discovery for synthetic biology and chemical processes.
PhD and publication record in computational biology/chemistry/systems biology/chemical engineering or adjacent field; demonstrated independent research and cross-disciplinary breadth; ability to drive publication-quality research.
3+ YOEPhD in bioinformatics/computational biology/systems biology, 3+ years industry or postdoc experience; strong RNA-seq, scRNA-seq, and long-read sequencing (Nanopore/PacBio) analysis; Python/R, Linux, HPC/AWS proficiency; reproducible research skills.
Cultivarium: Developing tools to engineer non-model microorganisms for research.
Master's in computational biology or related; authorized to work in the U.K.; experience with population- and comparative-genomics at population scale using tools like GATK, bcftools, vcftools, PLINK, ANGSD, scikit-allel; pipelines (Nextflow, Snakemake); Python/R, Biopython/Bioconductor/pandas, and Git; familiarity with organellar genomics.
Broad Institute: Conducts genomic research to understand and treat human diseases.
2+ YOEBS+2 years or MS in CS/Engineering/Biology/Bioinformatics; Python or R; experience with single-cell or spatial multi-omics; ML/deep learning knowledge; pipeline development and independent analysis experience.
Pioneer Valley Performing Arts Charter Public School: Public charter school providing academic and performing arts education
BA required, pass CORI/SORI and fingerprinting, computer literate, eligible for MA teacher certification or pass MTEL within 1 year; SEI endorsement preferred; teaching and curriculum planning experience preferred.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)
South San Francisco or Cambridge or Thousand Oaks
$190k-$257k/yrHybridFull Time
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
4+ YOEPhD with 4+ yrs or MS with 7+ yrs or BS with 9+ yrs in computational biology/biomedical data; strong R/Python; cardiovascular/metabolic focus; matrixed environment experience.
Senior / Principal Scientist, Structural Biology — Target Druggability & Structure-Based Drug Design
Framingham or New York City
$135k-$190k/yrOnsiteFull Time
SchrödingerNASDAQ: SDGR: Computational platform for drug discovery and materials science.
PhD or equivalent experience; deep hands-on structure-based drug design expertise; computational structural biology fluency; and cryo-EM or X-ray crystallography experience.
Part-Time Lecturer (non-tenure track) for Bio 35 – Computational Biology
Medford, Massachusetts, United States
$12k/yrOnsitePart Time
Tufts University: Private research university offering undergraduate, graduate, and professional programs.
Ph.D. required with teaching experience in computational biology, bioinformatics, or related areas; ability to teach introductory Python and develop inclusive classroom materials; evidence of teaching success.