135 office assistant jobs at 85 companies in Cayce, SC

1w
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Office Assistant
Columbia, South Carolina, United States
OnsiteFull Time
Richland County School District One
Richland County School District One: Providing K-12 public education to students in Richland County.
1+ YOEHigh school diploma plus one year of data entry experience, or equivalent education, training, and experience. Requires office equipment, communication, data entry, reporting, and organizational skills.
Microsoft Excel, Internet, email, printer, scanner, copier, adding machine, telephone
1w
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Sumter Office Assistant
Sumter, South Carolina, United States
OnsitePart Time, Temporary
Clemson University
Clemson University: Public research university providing higher education and degree programs.
High school diploma required; related clerical experience may substitute. Requires customer assistance, phone routing, sample processing, and fundamental knowledge of clerical procedures.
3mo
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Medical Office Assistant
Orangeburg, South Carolina, United States
OnsiteFull Time
Medical University of South Carolina
Medical University of South Carolina: Providing medical education, clinical care, and biomedical research.
1+ YOEHigh school diploma or equivalent plus one year patient care experience; CNA; nursing assistant/medical assistant course; EMT/Paramedic; or bachelor's degree.
1w
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Office Assistant, Available 2026 - 2027 School Year
Columbia, South Carolina, United States
OnsiteFull Time, Temporary
Richland County School District Two
Richland County School District Two: A public school district providing K-12 education in South Carolina.
The posting identifies a full-time, 185-day office assistant position at Kelly Mill Middle School for the 2026–2027 school year; specific qualifications are not provided.
3w
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Office Administrative Assistant - Sales
Columbia, South Carolina, United States
$19/hr OnsitePart Time
Tom James
Tom James: Manufactures and retails custom-made professional and formal apparel.
10-20 hrs/week, valid driver’s license, social media and Microsoft/Google proficiency, ability to lift 30 lbs, customer service and organizational skills; 2 years office experience preferred.
LinkedIn, Instagram, Facebook, Threads, Twitter, Microsoft Office, Google Docs, Google Sheets, Google Forms
2mo
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Attendance Clerk/Office Assistant 2026-2027
Williston, South Carolina, United States
OnsiteFull Time
Barnwell County School District
Barnwell County School District: Providing public K-12 education services in Barnwell County.
High school diploma required (BA/BS preferred). Strong communication, record-keeping, and clerical skills. Must provide three references including at least two supervisors. Ability to manage attendance records and prepare reports.
1w
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Branch Office Administrator
West Columbia, South Carolina, United States
$21-$23/hr OnsiteFull Time
Edward Jones
Edward Jones: Provides personalized financial advice and wealth management services.
Provides client service, account administration, scheduling, correspondence, marketing support, and operational assistance while learning financial services and firm technologies.
MoneyGuide, Salesforce, Microsoft Office
3mo
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Office RN (Columbia, SC, US, 29229)
Columbia or United States
OnsiteFull Time
Lexington Medical Center
Lexington Medical Center: Provides comprehensive healthcare and hospital services in South Carolina.
0+ YOEProvides nursing care; assists with procedures; administers injections; phlebotomy; CPR; patient education; scheduling and recordkeeping.
1mo
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Administrative Assistant - 5th Circuit Public Defender Office
Richland County, South Carolina, United States
$45k/yr OnsiteFull Time
State of South Carolina
State of South Carolina: Providing government administration and public services for South Carolina.
High school diploma and professional office experience; knowledge of office management, case and budget recordkeeping, ability to communicate, train staff, and follow policies; valid driver's license required.
Microsoft Word, Microsoft Excel, Microsoft Outlook, Microsoft PowerPoint, Defender Data, Case Management Software
2mo
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Aviation Safety Assistant (Office Automation)
West Columbia, South Carolina, United States
$45k-$66k/yr OnsiteFull Time
Federal Aviation Administration
Federal Aviation Administration: Regulates civil aviation and manages national air traffic systems.
1+ YOEPerform varied administrative and technical support for FAA programs: process airman/operator certificates, examine applications for FAR compliance, support test examiners, maintain files, prepare correspondence and reports, and use FAA automated databases.
Program Tracking and Reporting Subsystems (PTRS), Operations Specifications Subsystems (OPSS), Vital Information Subsystem (VIS), Enforcement Information System (EIS), National Data Base (NDB)
4d
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Assistant Manager, Branch Office - Forest Acres
Columbia, South Carolina, United States
$29-$37/hr OnsiteFull Time
Navy Federal Credit Union
Navy Federal Credit Union: Offers banking and financial services to the military community.
Requires branch operations knowledge, financial product and regulatory familiarity, cash and ATM operations experience, leadership exposure, customer service skills, communication, organization, and spreadsheet proficiency.
3mo
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Community Assistant
Columbia, South Carolina, United States
OnsitePart Time
College Town Communities
College Town Communities: Property management and leasing operator
Part-time community assistant for leasing office and resident experience; positive, self-starting.
2w
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Traveling Dental Assistant Periodontics
Columbia, South Carolina, United States
$20-$28/hr FieldFull Time, Part Time
PDS Health
PDS Health: Provides business and administrative support services to dental practices.
State-mandated dental assistant certification, high school diploma or GED, reliable transportation/driver's license for travel between offices, ability to perform clinical and administrative dental assistant tasks.
3w
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Disbursement Assistant
Columbia, South Carolina, United States
$18-$20/hr OnsiteFull Time
The Jeffcoat Firm
The Jeffcoat Firm: Providing personal injury and criminal defense legal services in South Carolina.
High school diploma required; strong communication, writing, organization, attention to detail; proficiency with Microsoft Office; ability to follow structured workflows and perform repetitive administrative tasks.
Microsoft Office
1w
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Loan Officer Assistant
Elgin, South Carolina, United States
$19-$23/hr OnsiteFull Time
Guild Mortgage
Guild Mortgage: Provides residential mortgage lending and loan servicing.
2+ YOEHigh school diploma or equivalent, two years of mortgage lending or related experience, NMLS required, strong organization and communication skills, and Microsoft Office proficiency.
Microsoft Office Suite, Microsoft Word, Microsoft Excel, Wiki, cloud-based programs, third-party software applications
2mo
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Administrative Assistant
Columbia, South Carolina, United States
$16/hr OnsiteFull Time
Community Options
Community Options: Provides housing and employment support for people with disabilities.
2+ YOEHigh school diploma/GED, 2 years related administrative experience, valid driver’s license, proficiency in Microsoft Office, strong interpersonal and communication skills, ability to prioritize and pass background/drug checks.
Microsoft Office
2mo
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Assistant Manager
Columbia, South Carolina, United States
OnsiteFull Time
Urban Air Adventure Park
Urban Air Adventure Park: Operates indoor adventure parks with diverse physical attractions.
1+ MgmtHospitality experience required, 1+ year supervisory/management experience, CPR/First Aid preferred, Microsoft Office skills, ability to work weekends/evenings/holidays, lift up to 30 lbs, pass background check.
Microsoft Office, Microsoft Excel, Microsoft Word, Microsoft PowerPoint
3w
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New Homebuilder Administrative Assistant
Columbia, South Carolina, United States
OnsiteFull Time
Adams Homes
Adams Homes: A leading new homebuilder delivering quality, affordable homes across the Southeast.
2+ years office administrative experience preferred; strong Microsoft Office (Word, Excel) skills, excellent communication, reliable transportation, ability to interact with customers and partners, and manage permit documentation.
Microsoft Office, Microsoft Word, Microsoft Excel
1mo
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2026-2027 - School Counseling Assistant
Irmo, South Carolina, United States
OnsiteFull Time
School District Five of Lexington and Richland Counties
School District Five of Lexington and Richland Counties: Provides public K-12 education and academic programs.
Provides counseling office support by assisting students, maintaining student records, and supporting school counselors; work during the 2026-2027 school year.
2d
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LEAD ADMIN ASSISTANT
Columbia, South Carolina, United States
$37k-$46k/yr OnsiteFull Time
City of Columbia
City of Columbia: The municipal government of the capital of South Carolina.
3+ YOEHigh school diploma or GED, three years of relevant experience, Microsoft Office skills, and a valid South Carolina Class D driver's license; typing speed may be required.
Microsoft Office