149 office assistant jobs at 91 companies in Irmo, SC
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Office Assistant
Columbia, South Carolina, United States
$22k-$31k/yrOnsiteFull Time
Richland County School District One: Public school district serving Richland County, South Carolina.
1+ YOEHigh school diploma plus one year of data entry experience, or equivalent education, training, and experience. Requires computer, clerical, communication, organization, and office equipment skills.
MUSC Health Orangeburg: County-owned public acute-care hospital system serving patients across Orangeburg, Calhoun, and Bamberg counties under MUSC oversight.
2+ YOEHigh school diploma or GED and two years of relevant experience required. Supports physicians and nurses, assists patients, manages registration, and schedules appointments.
Office Assistant, Available 2026 - 2027 School Year
Columbia, South Carolina, United States
OnsiteFull Time, Temporary
Richland County School District Two: Public school district serving students in Richland County, South Carolina.
The posting identifies a full-time, 185-day office assistant position at Kelly Mill Middle School for the 2026–2027 school year; specific qualifications are not provided.
Lexington Medical Center: Comprehensive teaching hospital network serving South Carolina's Midlands.
0.5+ YOEHigh School Diploma or equivalent; 6 months in admin/customer service; substitution: Medical Office Administrative Assistant certificate; none for licensure.
Tom James Company: Employee-owned manufacturer and retailer of custom clothing for busy professional men and women.
10-20 hrs/week, valid driver’s license, social media and Microsoft/Google proficiency, ability to lift 30 lbs, customer service and organizational skills; 2 years office experience preferred.
LinkedIn, Instagram, Facebook, Threads, Twitter, Microsoft Office, Google Docs, Google Sheets, Google Forms
Barnwell County Consolidated School District: Public South Carolina school district educating about 3,200 county students through elementary, middle, high-school, and career programs.
High school diploma required (BA/BS preferred). Strong communication, record-keeping, and clerical skills. Must provide three references including at least two supervisors. Ability to manage attendance records and prepare reports.
Administrative Assistant - 5th Circuit Public Defender Office
Richland County, South Carolina, United States
$45k/yrOnsiteFull Time
State of South Carolina: Official state government portal for the State of South Carolina.
High school diploma and professional office experience; knowledge of office management, case and budget recordkeeping, ability to communicate, train staff, and follow policies; valid driver's license required.
Microsoft Word, Microsoft Excel, Microsoft Outlook, Microsoft PowerPoint, Defender Data, Case Management Software
Federal Aviation Administration: U.S. agency regulating civil aviation and national airspace.
1+ YOEPerform varied administrative and technical support for FAA programs: process airman/operator certificates, examine applications for FAR compliance, support test examiners, maintain files, prepare correspondence and reports, and use FAA automated databases.
Program Tracking and Reporting Subsystems (PTRS), Operations Specifications Subsystems (OPSS), Vital Information Subsystem (VIS), Enforcement Information System (EIS), National Data Base (NDB)
Navy Federal Credit Union: Member-owned, not-for-profit credit union providing banking, lending, and investment services to servicemembers, veterans, DoD personnel, and families.
Requires branch operations knowledge, financial product and regulatory familiarity, cash and ATM operations experience, leadership exposure, customer service skills, communication, organization, and spreadsheet proficiency.
Grow Early Learning: Nonprofit Head Start provider serving farmworker children and families with early childhood education and family support.
5+ YOEHigh school diploma/GED and 5 years of verifiable administrative experience required. Associate's degree with 1 year of office experience preferred; Microsoft Office Suite proficiency required.
Pacific Dental Services: Integrated healthcare support organization for clinical practices.
High school/GED and state-mandated dental assistant credential required; must follow infection-control, assist clinicians, complete digital charting, and be able to travel between offices; valid driver\u0002s license or reliable transportation required for specialty roles.
School District of Newberry County: Public South Carolina school district serving PK–12 students across Newberry County through schools, career education, and adult education.
High school diploma with ParaPro pass or 2-year degree/60 college hours; ability to assist teachers, perform clerical tasks, supervise students, and operate office equipment.
The Jeffcoat Firm: South Carolina personal injury law firm representing accident victims and families in injury, wrongful-death, and related claims.
High school diploma required; strong communication, writing, organization, attention to detail; proficiency with Microsoft Office; ability to follow structured workflows and perform repetitive administrative tasks.
McCrory Construction: South Carolina's oldest general contractor serving public and private-sector clients across the Southeast.
Commercial construction experience, construction methods and safety knowledge, blueprint interpretation, organizational and communication skills, construction software and MS Office proficiency, and high school diploma or equivalent.
Guild Mortgage CompanyNYSE: GHLD: Providing residential home loans and in-house origination and servicing to homebuyers.
2+ YOEHigh school diploma or equivalent, two years of mortgage lending or related experience, NMLS required, strong organization and communication skills, and Microsoft Office proficiency.
Microsoft Office Suite, Microsoft Word, Microsoft Excel, Wiki, cloud-based programs, third-party software applications
Community Options: National nonprofit providing housing and employment support for individuals with disabilities.
2+ YOEHigh school diploma or GED, two years of related administrative experience, valid driver's license with satisfactory record, Microsoft Office Suite proficiency, strong communication, interpersonal, organizational, and time management skills.
Carolina Poly: A private South Carolina manufacturer producing polyethylene products, including trash bags and construction films.
Perform heavy data entry, prepare reports, screen calls, provide administrative support to multiple managers, be proficient in Microsoft Office/Excel and AS400, work independently, and spend time on the plant floor when needed.
Urban Air Adventure Parks: The nation's premier full-service active family entertainment.
1+ MgmtHospitality experience required, 1+ year supervisory/management experience, CPR/First Aid preferred, Microsoft Office skills, ability to work weekends/evenings/holidays, lift up to 30 lbs, pass background check.
Microsoft Office, Microsoft Excel, Microsoft Word, Microsoft PowerPoint
Foundation Partners Group: Privately held U.S. operator of funeral homes, cremation centers, and cemeteries serving families through end-of-life care.
3+ YOEHigh school diploma or equivalent, 3+ years in a small business office environment, Microsoft Office Suite knowledge, computer systems proficiency, accuracy, attention to detail, and strong follow-through.
Microsoft Office Suite, Microsoft Word, Microsoft Excel, Microsoft PowerPoint, Microsoft Outlook