82 principal scientist jobs at 24 companies in Dranesville, VA
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Principal Computer Scientist
Reston, Virginia, United States
OnsiteFull Time
20+ YOETS/SCI with Poly, Master’s in a technical field, 20+ years in data science/ML, Python/R/SQL, data visualization, DoD/IC knowledge.
Python, R, SQL, Power BI, Tableau, SPARQL, GraphQL
2mo
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Principal Data Scientist
Gaithersburg, Maryland, United States
$175k-$215k/yr RemoteFull Time
5+ YOEAdvanced degree (MS/PhD) in a quantitative field, 5+ years post-graduate life sciences analytics experience, proficiency in Python, hands-on omics and LLM/NLP experience, strong communication and client-facing skills, U.S. work authorization required.
bfPREP™, bfLEAP™, bfARENAS™, Python, LLMs, NLP, AWS, Google Cloud
2w
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
Bachelor's degree in a scientific field and considerable pharmaceutical industry experience, including clinical trial interpretation, autoimmune disease knowledge, cross-functional leadership, GCP, ICH, regulatory, and project management expertise.
GCP, ICH, CSRs, CTDs, INDs
2w
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
Bachelor's degree in a scientific field, substantial pharmaceutical industry and drug development experience, clinical trial interpretation, autoimmune disease knowledge, and leadership of complex clinical projects.
GCP, ICH, CSRs, CTDs, INDs
1mo
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Sr. Principal Scientist (Sr. Director) - Regulatory Liaison
Rahway or Rockville or Boston or North Wales
$191k-$300k/yr HybridFull Time
7+ YOEAdvanced degree in biological science and 7–10+ years drug development experience with majority in regulatory affairs; strong leadership, communication, and global regulatory strategy skills.
Co-pilot, ChatGPT
4d
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Digital Twin Principal Scientist (f/m/d)
Washington, District of Columbia, United States
OnsiteFull Time
Master’s in physics required, with Ph.D. preferred; deep IFE/ICF physics expertise; physics simulation code development and validation; strong Python, Fortran, or C++ skills; HPC and integrated systems modeling experience.
Python, Fortran, C++, HPC, Digital Twin, PIC, Monte Carlo
3mo
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Principal Research Scientist - Autonomous Systems
Basking Ridge or Annapolis Junction or Silver Spring
$146k-$234k/yr OnsiteFull Time
7+ YOEMinimum 7 years of experience with a PhD; strong background in AI, cybersecurity, and autonomous systems; hands-on AI development; excellent communication; US citizenship and ability to obtain/maintain a Secret clearance.
PyTorch, TensorFlow
1mo
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Principal Health Data Scientist
United States or Bowie
$132k-$176k/yr RemoteFull Time
7+ YOE7+ years in healthcare/pharma data with expertise in claims/EHR, advanced SQL/Snowflake, statistical tools, problem solving, project management, and ability to work independently.
SQL, Snowflake, SAS, R, MatLab
1mo
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Principal Scientist- Search
New York City or San Francisco or Los Angeles or Irvine or McLean or Washington
$212k-$394k/yr HybridFull Time
8+ YOEPhD and 8+ years building and deploying production AI systems; deep expertise in information retrieval, search, NLP, RAG, knowledge graphs, LLMs; strong product sense and leadership skills.
Python, PyTorch, Hugging Face, Azure ML, Azure AI Foundry, AWS SageMaker
1mo
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Principal Data Scientist
Annapolis Junction, Maryland, United States
$150k-$210k/yr OnsiteFull Time
8+ YOEActive TS/SCI with polygraph, Bachelor\u0002s degree (or advanced degree in lieu of years) and 8+ years' experience, proficiency in Python, Docker, Kubernetes, ML, defensive cyber operations, and data engineering.
Python, Docker, Kubernetes, SQL, R, AWS, Jupyter Notebooks, Linux, Windows, Big Data Platform (BDP), STIGs, IAVA, Network Analysis Tools, Cisco
6d
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Data Scientist Principal
Chantilly, Virginia, United States
OnsiteFull Time
5+ YOEBachelor’s plus 9 years, master’s plus 7, or doctorate/JD plus 4; equivalent experience accepted. Requires 5+ years in software engineering, data analytics, machine learning, statistics, and active Top Secret/SCI with Poly.
Microsoft Office, Artificial intelligence (AI), Machine learning (ML)
1mo
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Principal Data Scientist
Annapolis Junction, Maryland, United States
$150k-$210k/yr OnsiteFull Time
8+ YOEActive TS/SCI with polygraph, Bachelor's +8 years (or advanced degree in lieu), proficient in Python, Docker, Kubernetes; 3+ years Defensive Cyber Ops and 3+ years ML experience; experience with databases and large-scale data workflows.
Python, Docker, Kubernetes, R, SQL, AWS, Big Data Platform (BDP), Jupyter Notebooks, Ubuntu, CentOS, RHEL, Windows
3w
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Principal Regulatory Scientist
Reston, Virginia, United States
$116k-$181k/yr OnsiteFull Time
4+ YOEDoctorate in a relevant scientific discipline with ≥4 years experience (or master’s with ≥6 years); demonstrated FDA regulatory experience; strong writing, communication, analytical skills; US citizenship and active secret clearance required.
3mo
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Oligo Discovery Chemistry Principal Scientist
Cambridge or Waltham or Rockville or San Francisco
$121k-$202k/yr OnsiteFull Time
3+ YOEPhD with 3+ years in chemistry/oligonucleotide synthesis; 2+ years industry experience in synthetic chemistry; expertise in SPOS oligo synthesis and RNA therapeutics; leadership and mentorship experience.
ÅKTA Oligosynt, Cytiva, Unicorn, LC/HRMS, UPHLC, LC/MS
1mo
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Senior Principal Data Scientist - AI Lead (R-19518)
Vienna, Virginia, United States
HybridFull Time
10+ YOE10+ years data science/ML experience, AI/ML and NLP expertise, leadership experience, proven AI solution delivery for public sector, proficiency in Python/Java/Go and cloud platforms (AWS/Azure/GCP), Bachelor's required, Advanced degree preferred.
Python, Java, Go, AWS, Azure, GCP
1w
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Principal Data Scientist - Remote
United States or Minnetonka or Minnesota or Washington, D.C.
$113k-$193k/yr RemoteFull Time
10+ YOE10+ years designing production ML solutions; 3+ years building LLM applications; deep NLP or computer vision expertise; Python, deep learning, cloud ML, Docker/Kubernetes, and MLOps experience required.
LangChain, LangGraph, AWS, Azure, GCP, Docker, Kubernetes, Python, PyTorch, TensorFlow, MLflow, Kubeflow, TFX, Airflow, Apache Spark, Hadoop, Dask, Tableau, Power BI, LLM, GANs
2mo
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Data Scientist, Principal (DCO) Senior
Annapolis Junction, Maryland, United States
OnsiteFull Time
10+ YOERequires 10+ years experience (varies by degree), 3+ years Defensive Cyber Operations, 3+ years machine learning, proficiency in Python, Docker, Kubernetes, experience with end-to-end workflows, and ability to implement models into production. TS/SCI with polygraph required.
Python, Docker, Kubernetes, R, SQL, AWS (Amazon Web Services), Jupyter Notebooks, Network Analysis Tools, Big Data Platform (BDP), Linux, Ubuntu, CentOS, RHEL, Windows, Cisco CCNA, STIGs, IAVA
2mo
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Principal Data Scientist - Gen AI
Waltham or North Bethesda
$200k-$230k/yr HybridFull Time
10+ YOE10+ years applied ML/data science or PhD+6 years; bachelor's required (advanced degree preferred); expert Python, PyTorch, TensorFlow, pandas, numpy; experience with LLMs, multimodal data, AWS/SageMaker; leadership and roadmap ownership.
Python, PyTorch, TensorFlow, pandas, numpy, Amazon Web Services (AWS), AWS SageMaker, Transformers, GPT, Teamcenter, Designcenter
1w
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Principal Applied Scientist - TS/SCI
Herndon, Virginia, United States
$140k-$206k/yr OnsiteFull Time
12+ YOEU.S. citizen with active TS/SCI clearance and ability to obtain CI polygraph; 12+ years’ experience; master's or PhD; modeling, statistics, physics-based modeling, Python, scientific computing, and AI/ML experience.
Python, scientific computing libraries, AI/ML
1mo
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Principal Research Scientist, Evidence & Strategy
United States or Washington
$168k-$215k/yr RemoteFull Time
10+ YOEBA/BS or higher; 10+ years SAS or SQL experience; experience with large pharmacy and medical claims databases; advanced statistical/econometric methods; strong communication and independent project management.
SAS, SQL, SAS Macros, Visual Basic for Applications (VBA)
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