82 principal scientist jobs at 21 companies in Frederick, MD
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Principal Data Scientist
Gaithersburg, Maryland, United States
$175k-$215k/yr RemoteFull Time
5+ YOEAdvanced degree (MS/PhD) in a quantitative field, 5+ years post-graduate life sciences analytics experience, proficiency in Python, hands-on omics and LLM/NLP experience, strong communication and client-facing skills, U.S. work authorization required.
bfPREP™, bfLEAP™, bfARENAS™, Python, LLMs, NLP, AWS, Google Cloud
2mo
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Principal Computer Scientist
Reston, Virginia, United States
OnsiteFull Time
20+ YOETS/SCI with Poly, Master’s in a technical field, 20+ years in data science/ML, Python/R/SQL, data visualization, DoD/IC knowledge.
Python, R, SQL, Power BI, Tableau, SPARQL, GraphQL
6d
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
Bachelor's degree in a scientific field and considerable pharmaceutical industry experience, including clinical trial interpretation, autoimmune disease knowledge, cross-functional leadership, GCP, ICH, regulatory, and project management expertise.
GCP, ICH, CSRs, CTDs, INDs
6d
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
Bachelor's degree in a scientific field, substantial pharmaceutical industry and drug development experience, clinical trial interpretation, autoimmune disease knowledge, and leadership of complex clinical projects.
GCP, ICH, CSRs, CTDs, INDs
1mo
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Sr Principal Scientist - Standardized Organoid Modeling Center
Frederick, Maryland, United States
$166k-$238k/yr OnsiteFull Time
10+ YOEPhD required with 10+ years in hepatic organoid biology, proven laboratory leadership and mentoring, publication record, Microsoft Office skills, and ability to obtain/maintain a security clearance.
Microsoft Office
1w
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Principal Scientist, Oncology Data Science (Translational Science)
Pennsylvania or United Kingdom or Stevenage or Heidelberg or Massachusetts or Cambridge or Upper Providence or Waltham or Maryland or Rockville or San Francisco or Germany
$121k-$202k/yr HybridFull Time
1+ YOEPhD or equivalent in a quantitative field, 1+ year industry or postdoctoral experience, cancer computational biology expertise, single-cell omics, statistical and machine learning, Python, and PyTorch.
Python, PyTorch, R, CI/CD, CRISPR, Perturb-seq, version control
3mo
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Principal Research Scientist - Autonomous Systems
Basking Ridge or Annapolis Junction or Silver Spring
$146k-$234k/yr OnsiteFull Time
7+ YOEMinimum 7 years of experience with a PhD; strong background in AI, cybersecurity, and autonomous systems; hands-on AI development; excellent communication; US citizenship and ability to obtain/maintain a Secret clearance.
PyTorch, TensorFlow
4w
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Principal Health Data Scientist
United States or Bowie
$132k-$176k/yr RemoteFull Time
7+ YOE7+ years in healthcare/pharma data with expertise in claims/EHR, advanced SQL/Snowflake, statistical tools, problem solving, project management, and ability to work independently.
SQL, Snowflake, SAS, R, MatLab
1mo
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Principal Scientist- Search
New York City or San Francisco or Los Angeles or Irvine or McLean or Washington
$212k-$394k/yr HybridFull Time
8+ YOEPhD and 8+ years building and deploying production AI systems; deep expertise in information retrieval, search, NLP, RAG, knowledge graphs, LLMs; strong product sense and leadership skills.
Python, PyTorch, Hugging Face, Azure ML, Azure AI Foundry, AWS SageMaker
1w
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
Bachelor's degree in a scientific field and considerable pharmaceutical drug development experience, including clinical trial interpretation. Knowledge of autoimmune diseases required; advanced degree and leadership experience preferred.
Good Clinical Practice (GCP), International Council for Harmonisation (ICH), Clinical Study Reports (CSRs), Common Technical Documents (CTDs), Investigational New Drugs (INDs)
3d
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Principal Health Scientist
Washington, District of Columbia, United States
$175k-$275k/yr OnsiteFull Time
15+ YOERequires risk assessment experience, DABT or 15+ years in epidemiology, scientific publications, an MS or doctorate in a related field, strong technical and lay writing, and current and future U.S. work authorization.
Key Performance Indicators (KPI)
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Principal Data Scientist
Annapolis Junction, Maryland, United States
$150k-$210k/yr OnsiteFull Time
8+ YOEActive TS/SCI with polygraph, Bachelor's +8 years (or advanced degree in lieu), proficient in Python, Docker, Kubernetes; 3+ years Defensive Cyber Ops and 3+ years ML experience; experience with databases and large-scale data workflows.
Python, Docker, Kubernetes, R, SQL, AWS, Big Data Platform (BDP), Jupyter Notebooks, Ubuntu, CentOS, RHEL, Windows
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Principal Regulatory Scientist
Reston, Virginia, United States
$116k-$181k/yr OnsiteFull Time
4+ YOEDoctorate in a relevant scientific discipline with ≥4 years experience (or master’s with ≥6 years); demonstrated FDA regulatory experience; strong writing, communication, analytical skills; US citizenship and active secret clearance required.
1mo
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Principal Data Scientist
Annapolis Junction, Maryland, United States
$150k-$210k/yr OnsiteFull Time
8+ YOEActive TS/SCI with polygraph, Bachelor\u0002s degree (or advanced degree in lieu of years) and 8+ years' experience, proficiency in Python, Docker, Kubernetes, ML, defensive cyber operations, and data engineering.
Python, Docker, Kubernetes, SQL, R, AWS, Jupyter Notebooks, Linux, Windows, Big Data Platform (BDP), STIGs, IAVA, Network Analysis Tools, Cisco
1mo
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Senior Principal Data Scientist - AI Lead (R-19518)
Vienna, Virginia, United States
HybridFull Time
10+ YOE10+ years data science/ML experience, AI/ML and NLP expertise, leadership experience, proven AI solution delivery for public sector, proficiency in Python/Java/Go and cloud platforms (AWS/Azure/GCP), Bachelor's required, Advanced degree preferred.
Python, Java, Go, AWS, Azure, GCP
2mo
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Principal Data Scientist - Gen AI
Waltham or North Bethesda
$200k-$230k/yr HybridFull Time
10+ YOE10+ years applied ML/data science or PhD+6 years; bachelor's required (advanced degree preferred); expert Python, PyTorch, TensorFlow, pandas, numpy; experience with LLMs, multimodal data, AWS/SageMaker; leadership and roadmap ownership.
Python, PyTorch, TensorFlow, pandas, numpy, Amazon Web Services (AWS), AWS SageMaker, Transformers, GPT, Teamcenter, Designcenter
1mo
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Data Scientist, Principal (DCO) Senior
Annapolis Junction, Maryland, United States
OnsiteFull Time
10+ YOERequires 10+ years experience (varies by degree), 3+ years Defensive Cyber Operations, 3+ years machine learning, proficiency in Python, Docker, Kubernetes, experience with end-to-end workflows, and ability to implement models into production. TS/SCI with polygraph required.
Python, Docker, Kubernetes, R, SQL, AWS (Amazon Web Services), Jupyter Notebooks, Network Analysis Tools, Big Data Platform (BDP), Linux, Ubuntu, CentOS, RHEL, Windows, Cisco CCNA, STIGs, IAVA
1d
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Principal Applied Scientist - TS/SCI
Herndon, Virginia, United States
$140k-$206k/yr OnsiteFull Time
12+ YOEU.S. citizen with active TS/SCI clearance and ability to obtain CI polygraph; 12+ years’ experience; master's or PhD; modeling, statistics, physics-based modeling, Python, scientific computing, and AI/ML experience.
Python, scientific computing libraries, AI/ML
1mo
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Principal Data Scientist - Recommendation & Personalization Systems
McLean or New York City or San Jose
$162k-$201k/yr OnsiteFull Time
3+ YOEAdvanced quantitative degree and multi-year analytics experience (Bachelor+5, Master+3, or PhD), expertise in Python/ML, experience with AWS, Spark, SQL; strong communication and product orientation.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
1w
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Principal Associate, Data Scientist - Card Intelligence
McLean or New York City or Cambridge
$162k-$201k/yr OnsiteFull Time
5+ YOEBachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD in a quantitative field; data analytics, machine learning, Python, SQL, and cloud experience required or preferred.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
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