73 principal scientist jobs at 26 companies in Islip, NY

3mo
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Principal Data Scientist
Jersey City or Tampa
HybridFull Time
DTCC
DTCC: Provides post-trade infrastructure for the global financial services industry
8+ YOEMinimum 8 years of related experience; Bachelor's degree (preferred) or equivalent experience.
Python, Snowflake, Machine Learning, Data Visualization, Governance
2mo
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Principal/Senior - Data Scientist – New York City
New York City, New York, United States
HybridFull Time
Aily Labs
Aily Labs: AI-powered decision intelligence platform for large enterprises.
Senior/Lead Data Scientist with 4+ years; Principal with 6+ years; strong MLOps, Python/SQL, domain expertise; ability to lead projects and mentor teammates.
Python, SQL, MLOps, Knowledge Graph
1mo
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Principal Scientist – Data Insights & Hypothesis Design
Chicago or Redwood City or New York City or California or New York
$150k-$200k/yr HybridFull Time
Tempus AI
Tempus AINASDAQ: TEM: Builds a data platform for AI-powered precision medicine diagnostics.
6+ YOEPhD in NGS-related field,6+ years industry experience,domain expertise in oncology/neurology/immunology,large-scale clinico-genomic analysis,SQL/Python/R proficiency,and experience translating data into production products.
SQL, R, Python, Tempus Data Model (TDM)
3mo
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Principal Scientist – Antibody Discovery/Protein Design
Branford, Connecticut, United States
OnsiteFull Time
EvolveImmune Therapeutics
EvolveImmune Therapeutics: Developing next-generation T cell engagers for cancer immunotherapy.
5+ YOEPhD in biochemistry, computational biology, or structural biology with 5+ years antibody/biotherapeutic engineering experience; AI/ML protein design; antibody display tech; multispecific protein design; strong cross-functional collaboration.
AI/ML, Yeast display, Phage display, Antibody engineering, Biophysical characterization, Multispecific protein design
2d
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Principal Scientist, Hearing Loss and Vestibular Disorders
Tarrytown, New York, United States
$129k-$210k/yr OnsiteFull Time
Regeneron Pharmaceuticals
Regeneron PharmaceuticalsNASDAQ: REGN: Discovers and develops medicines for serious diseases.
5+ YOEPh.D. with 5+ years of relevant experience, innovation and publication record, drug development expertise, rigorous research skills, and effective independent and cross-functional communication.
in vivo, in vitro
2mo
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Principal Applied Scientist, Amazon Braket
Seattle or New York
$199k-$296k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Global online retail and cloud computing technology provider.
5+ YOEPhD in a technical field, 5+ years relevant experience, track record of publications, experience with multiple programming languages, and experience leading scientists and developing junior talent.
C++, Java, Perl, Python
1mo
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Principal Scientist- Search
New York City or San Francisco or Los Angeles or Irvine or McLean or Washington
$212k-$394k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
8+ YOEPhD and 8+ years building and deploying production AI systems; deep expertise in information retrieval, search, NLP, RAG, knowledge graphs, LLMs; strong product sense and leadership skills.
Python, PyTorch, Hugging Face, Azure ML, Azure AI Foundry, AWS SageMaker
2mo
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Principal Scientist - Clinical and Scientist Affairs
Melville, New York, United States
$110k-$125k/yr OnsiteFull Time
The Estée Lauder Companies
The Estée Lauder CompaniesNYSE: EL: Manufactures and markets prestige skincare, makeup, and fragrance products.
5+ YOEPhD or PharmD preferred (alternatively BS with extensive experience). 5+ years industry experience in dermatology/skin care or claims support, clinical testing, clinical method development, strong communication and cross-functional project management skills.
1mo
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Principal Data Scientist
United States or San Francisco or New York City
$143k-$275k/yr OnsiteFull Time
Microsoft
MicrosoftNASDAQ: MSFT: Develops software, services, devices, and cloud computing solutions.
5+ YOEAdvanced degree in quantitative field with multi-year data science experience (minimum 5+ yrs), experience managing structured/unstructured data, model evaluation, data acquisition, and strong communication skills; U.S. citizenship verification required.
1d
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Principal Data Scientist
San Francisco or New York City or Bellevue or Burbank
$228k-$423k/yr HybridFull Time
Warner Bros. Discovery
Warner Bros. DiscoveryNasdaq: WBD: Produces and distributes multimedia entertainment content and news worldwide.
8+ YOEMaster's degree in a quantitative field required; PhD preferred. Requires 8+ years in machine learning, AI, or data science, recommender systems expertise, SQL, big data, and Python-based ML platforms.
SQL, AWS, Snowflake, Spark, Google Cloud, Python, TensorFlow, Keras, PyTorch
1w
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Principal Measurement Scientist
Sydney or Auckland or New York City or London
$178k-$220k/yr HybridFull Time
Tracksuit
Tracksuit: Provides a SaaS platform for always-on brand health tracking.
10+ YOEAdvanced training in psychology, statistics, behavioral science, or similar; 10+ years in quantitative research or measurement science; expertise in survey methodology, measurement theory, psychometrics, and respondent psychology.
2w
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Principal Data Scientist
New York, New York, United States
OnsiteFull Time
Blink Health
Blink Health: Digital platform for affordable prescription medications and pharmacy access.
10+ YOE10+ years in data science or related quantitative field; expertise in statistical modeling, experimentation, causal inference, ML and modern AI (LLMs); expert SQL and strong programming in Python or R; experience with large datasets and BI tools.
large language models (LLMs), SQL, Python, R, Tableau, Databricks, Delta Lake, MLflow, Feature Store, Model Serving
2mo
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Principal Scientist - Clinical and Scientist Affairs (24337)
Melville or Houston
OnsiteFull Time
Estée Lauder Companies
Estée Lauder CompaniesNYSE: EL: Manufacturer and marketer of prestige beauty and skincare products.
No qualifications or responsibilities were provided in the job text.
3w
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Principal Scientist, Formulation Development (DPDT)
Tarrytown, New York, United States
$129k-$210k/yr OnsiteFull Time
Regeneron
RegeneronNasdaq: REGN: Discovers and manufactures medicines for serious diseases.
4+ YOEPhD or advanced degree with multi-year biopharma experience, expertise in formulation and bioconjugates, experience leading projects and mentoring staff, familiarity with regulatory guidelines and statistical software.
JMP, Electronic Laboratory Notebook (ELN), Scientific Data Management System (SDMS), LIMS, Electronic Document Management System (EDMS)
2w
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(USA) Principal, Data Scientist
Hoboken, New Jersey, United States
$132k-$264k/yr OnsiteFull Time
Walmart
WalmartNYSE: WMT: Multinational retail operating discount stores and supermarkets.
Advanced expertise in machine learning, statistics, data architecture; Bachelor's/Master's/experience-based qualification paths; strong Python and SQL skills; leadership and model deployment experience.
Python, SQL, Spark, Scala, R, scikit learn, tensorflow, torch
1mo
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(USA) Principal, Data Scientist
Sunnyvale or Hoboken or Bellevue
$143k-$286k/yr OnsiteFull Time
Walmart
WalmartNYSE: WMT: Operates a chain of hypermarkets, discount stores, and grocery stores.
10+ YOE5+ MgmtBachelor's, master's, or doctoral degree in a quantitative field, or 7 years' analytics experience; 5+ years of technical leadership; strong ML, Python, data platforms, deployment, and communication skills.
Python, R, GCP, Azure, PySpark, Google Cloud Platform, Vertex AI, Kubeflow, Hadoop, Hive, MapReduce, HQL, Scala, GPU, CUDA, scikit-learn, TensorFlow, Torch, NLP, LLM, vector databases, WCAG 2.2 AA
2w
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Principal Research Scientist - Risk
New York City, New York, United States
$180k-$220k/yr HybridFull Time
Neara
Neara: Provides digital twin simulation software for electric utility infrastructure.
PhD-level researcher with experience leading research, probabilistic modeling, uncertainty quantification, decision modeling, and building technical teams for infrastructure risk and resilience.
4d
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Senior/Principal Scientist, Radiochemistry
New York City, New York, United States
OnsiteFull Time
Actinium Pharmaceuticals
Actinium PharmaceuticalsNYSE American: ATNM: Developing targeted radiopharmaceutical therapies for cancer treatment.
8+ YOEPh.D. in chemistry, radiochemistry, nuclear chemistry, or related field; 8–10+ years developing radiotherapies or imaging agents; expertise in chelation, bioconjugation, radiolabeling, imaging, instrumentation, and regulatory submissions.
radio-HPLC, radio-TLC, gamma spectrometry, size-exclusion HPLC, LC-MS, PET, SPECT, DOTA, Ac-225, Lu-177, Zr-89, In-111, Cu-64, Ga-68, IND, IMPD, CRO
6d
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Senior Principal/ Principal Scientist, Computational Safety
Ridgefield, Connecticut, United States
$140k-$269k/yr OnsiteFull Time
Boehringer Ingelheim
Boehringer Ingelheim: Researches and develops pharmaceutical products for humans and animals.
7+ YOEPh.D. in a relevant computational or molecular field, 7+ years postdoctoral or industry experience, and at least 3 years in safety risk assessment; expertise in computational toxicology, AI/ML, and multi-omics.
AI/ML, multi-omics, Adverse Outcome Pathways, foundation models
2w
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Principal AI Scientist (Polytope Bio)
New York City or San Francisco
$250k-$350k/yr OnsiteFull Time
Astera Institute
Astera Institute: Conducts fundamental research in artificial intelligence and longevity science.
2+ YOEPhD or equivalent in ML/computational biology preferred; 2+ years post-PhD industry research experience; experience training models from scratch, reinforcement learning, transformers/diffusion models, and building training infrastructure.