66 principal scientist jobs at 18 companies in Sumner, WA
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Principal Experimental Scientist - RF
Everett, Washington, United States
$230k-$270k/yr OnsiteFull Time
10+ YOEPhD in physics, plasma physics, electrical engineering, or related field; 10+ years in lab/R&D with plasma systems; expertise in RF plasma sources and diagnostics.
RF hardware, Antenna design, Vacuum systems, Plasma diagnostics, RF-plasma interactions
2mo
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Lead Principal Applied Scientist
Santa Clara or Seattle or United States
$158k-$355k/yr OnsiteFull Time
10+ YOE10+ years applied ML/AI research experience; expertise in dataset preparation, experiment design, model training/fine-tuning, evaluation, deployment, and publication; strong coding, version control, and leadership skills.
1w
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Principal Scientist, Engineered Cell Therapy Discovery
Seattle, Washington, United States
$152k-$185k/yr OnsiteFull Time
4+ YOERequires a life sciences bachelor's degree with 8+ years, master's with 6+ years, or Ph.D. with 4+ years of experience. Expertise in immunology, engineered cell therapy, T-cell assays, gene delivery, and genetic construct design.
Electronic notebooks, lentiviral, retroviral, AAV, CAR T, eTCR T, multi-color flow cytometry, Gibson Assembly, Golden Gate, HT imaging, CRISPR, AI
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Principal Scientist, Engineered Cell Therapy Discovery
Seattle, Washington, United States
$152k-$185k/yr OnsiteFull Time
4+ YOEAdvanced life sciences expertise with 4+ years postdoctoral or industry experience, or equivalent degree-based experience. Requires engineered T-cell therapy, functional assay, gene delivery, construct design, and research leadership expertise.
CAR T, eTCR T, lentiviral, retroviral, AAV, multi-color flow cytometry, Gibson Assembly, Golden Gate, HT imaging, CRISPR, AI, electronic notebooks
3mo
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Principal Applied Scientist, Amazon Payments
Seattle, Washington, United States
$199k-$269k/yr OnsiteFull Time
10+ YOE2+ MgmtPhD or MSc in CS; 10+ years AI/ML; strong research, collaboration, delivery; leadership in teams; excellent communication.
Python, Machine Learning, Natural Language Processing, GenAI, TensorFlow, PyTorch
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Principal Data Scientist
San Francisco or New York City or Bellevue or Burbank
$228k-$423k/yr HybridFull Time
8+ YOEMaster's degree in a quantitative field required; PhD preferred. Requires 8+ years in machine learning, AI, or data science, recommender systems expertise, SQL, big data, and Python-based ML platforms.
SQL, AWS, Snowflake, Spark, Google Cloud, Python, TensorFlow, Keras, PyTorch
2mo
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Principal Data Scientist
Redmond, Washington, United States
$143k-$275k/yr HybridFull Time
5+ YOEAdvanced degree in a quantitative field with corresponding years of data-science experience (PhD+5, MS+7, BS+10) or equivalent; experience in content platforms, advertising/monetization, forecasting, experimentation, AI/ML, and strong stakeholder communication.
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Principal Data Scientist
Seattle, Washington, United States
$131k-$197k/yr OnsiteFull Time
10+ YOE10+ years building and deploying ML/AI solutions; strong Python and ML framework skills; expertise in forecasting, optimization, experimentation, and model lifecycle; experience with cloud platforms and visualization tools.
Python, Power BI, Plotly, Matplotlib, AWS, Azure, Snowflake, MLOps, CI/CD
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Principal Applied Scientist
Bellevue, Washington, United States
$200k-$250k/yr OnsiteFull Time
10+ YOEMS/PhD preferred in CS/ML/AI, 10+ years industry ML experience building production ML systems, strong Python, expertise with LLMs/foundation models, distributed training, model deployment, and excellent communication.
Python
2mo
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Principal, Data Scientist
Bellevue, Washington, United States
$132k-$264k/yr OnsiteFull Time
3+ YOEAdvanced ML and statistics expertise; experience architecting large-scale ML systems; strong Python and SQL skills; experience with Spark/Hive; PhD or Master’s with significant experience or extensive industry experience as specified.
Python, Java, Scala, SQL, Hive, Spark, Kaggle, scikit-learn, TensorFlow, PyTorch, R
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Principal, Data Scientist
Bellevue, Washington, United States
$132k-$264k/yr OnsiteFull Time
3+ YOEBachelor's degree with 5 years, master's degree with 3 years, or 7 years of analytics experience; advanced machine learning, statistics, Python, SQL/Hive, Spark, and stakeholder management skills required.
Python, Java, Scala, SQL, Hive, Spark, R, scikit-learn, TensorFlow, Torch, Kaggle, Microsoft Excel
2mo
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Principal Scientist, Immunology
San Francisco or Seattle
$175k-$190k/yr RemoteFull Time
8+ YOEPhD in immunology or related field with 8+ years industry experience; deep immunology expertise, drug development knowledge, experience with immunological assays (flow cytometry, ELISA/MSD), strong communication and publication record.
flow cytometry, ELISA/MSD, cytokine panels, cellular assays, single-cell, proteomics
2mo
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Senior/Principal Fisheries Scientist
Wenatchee or Seattle or Portland or Washington or Oregon or Idaho or California or Montana
$110k-$145k/yr RemoteFull Time
10+ YOEBachelor's in fisheries science/biology/ecology required (Masters/Doctorate preferred); 10+ years experience in Pacific Northwest salmonid issues; expertise in fish passage, ESA consultation, hatchery operations, study design, quantitative analysis, project management, and staff supervision; valid driver’s license.
1w
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Principal Scientist, Chemical Development
Bothell, Washington, United States
$170k-$206k/yr OnsiteFull Time
7+ YOEPhD in synthetic organic chemistry or similar and 7+ years of industry experience leading small-molecule or linker-payload programs; requires process development, tech transfer, cGMP, ICH, analytical, and cross-functional collaboration expertise.
2mo
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Principal AI/ML Applied Scientist
Seattle, Washington, United States
$267k-$350k/yr HybridFull Time
11+ YOEBachelor's in CS/data/engineering or equivalent; 11+ years AI/ML research experience; deep expertise in generative AI, NLP, computer vision, multimodal learning; experience with Python and PyTorch; ability to lead enterprise AI strategy and translate research to production.
Python, PyTorch
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Principal Research Scientist, Siri Innovation Studio
Seattle, Washington, United States
OnsiteFull Time
Expertise in machine learning modeling, incubating and deploying ML-driven features, collaborating across software/hardware/design teams, and building user-centered AI for assistants and speech products.
iOS, iPadOS, macOS, watchOS, visionOS
2d
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principal data scientist, Supply Chain Forecasting & Optimization
Seattle, Washington, United States
$166k-$276k/yr HybridFull Time
10+ YOE10+ years applying data science, forecasting, optimization, operations research, or machine learning; advanced Python, SQL, cloud analytics, and production ML expertise; strong communication and strategic leadership skills.
Python, SQL
4d
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principal data scientist, Supply Chain Forecasting & Optimization
Seattle, Washington, United States
$166k-$276k/yr HybridFull Time
10+ YOE10+ years in data science, forecasting, optimization, operations research, or machine learning; advanced Python, SQL, cloud analytics, and production ML proficiency; expertise in forecasting and model deployment.
Python, SQL
4d
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principal data scientist, Supply Chain Forecasting & Optimization
Seattle, Washington, United States
$166k-$276k/yr OnsiteFull Time
10+ YOE10+ years in data science, forecasting, optimization, operations research, or machine learning; advanced Python, SQL, cloud analytics, and production ML expertise; strong strategy and executive communication skills.
Python, SQL
3w
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Principal Machine Learning Scientist - Agentic Experiences
Seattle or San Jose
$224k-$339k/yr OnsiteFull Time
10+ YOEBS or equivalent,10+ years industry experience, proven experience building agentic/multi-step AI systems, strong Python and ML framework skills, experience with LLM APIs and orchestration, evaluation and productionization experience.
Python, PyTorch, TensorFlow, JAX, LLM APIs, LangChain, LlamaIndex
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