85 principal scientist jobs at 25 companies in Walker Mill, MD

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Principal Scientist
Andrews Air Force Base, Maryland, United States
$122k-$186k/yr OnsiteFull Time
Mission Support and Test Services: Manages and operates the Nevada National Security Site.
9+ YOEBachelor’s degree in health physics or nuclear engineering plus 9 years of relevant experience; strong communications; able to deploy worldwide; SCI/Q clearance required.
Office365, Word, Excel, Adobe Acrobat, Outlook
3mo
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Principal Computer Scientist
Reston, Virginia, United States
OnsiteFull Time
ANSER
ANSER: Provides research and analysis for national and homeland security missions.
20+ YOETS/SCI with Poly, Master’s in a technical field, 20+ years in data science/ML, Python/R/SQL, data visualization, DoD/IC knowledge.
Python, R, SQL, Power BI, Tableau, SPARQL, GraphQL
2mo
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Principal Data Scientist
Gaithersburg, Maryland, United States
$175k-$215k/yr RemoteFull Time
BullFrog AI
BullFrog AINASDAQ: BFRG: AI-powered platforms for drug discovery and clinical development.
5+ YOEAdvanced degree (MS/PhD) in a quantitative field, 5+ years post-graduate life sciences analytics experience, proficiency in Python, hands-on omics and LLM/NLP experience, strong communication and client-facing skills, U.S. work authorization required.
bfPREP™, bfLEAP™, bfARENAS™, Python, LLMs, NLP, AWS, Google Cloud
2w
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Global biopharmaceutical developing and manufacturing prescription medicines.
Bachelor's degree in a scientific field, substantial pharmaceutical industry and drug development experience, clinical trial interpretation, autoimmune disease knowledge, and leadership of complex clinical projects.
GCP, ICH, CSRs, CTDs, INDs
2w
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Researches and develops medicines to treat major diseases globally.
Bachelor's degree in a scientific field and considerable pharmaceutical industry experience, including clinical trial interpretation, autoimmune disease knowledge, cross-functional leadership, GCP, ICH, regulatory, and project management expertise.
GCP, ICH, CSRs, CTDs, INDs
3w
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Principal Scientist, Oncology Data Science (Translational Science)
Pennsylvania or United Kingdom or Stevenage or Heidelberg or Massachusetts or Cambridge or Upper Providence or Waltham or Maryland or Rockville or San Francisco or Germany
$121k-$202k/yr HybridFull Time
GSK
GSKLondon Stock Exchange: GSK: Develops and manufactures innovative vaccines and specialty medicines.
1+ YOEPhD or equivalent in a quantitative field, 1+ year industry or postdoctoral experience, cancer computational biology expertise, single-cell omics, statistical and machine learning, Python, and PyTorch.
Python, PyTorch, R, CI/CD, CRISPR, Perturb-seq, version control
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Sr. Principal Scientist (Sr. Director) - Regulatory Liaison
Rahway or Rockville or Boston or North Wales
$191k-$300k/yr HybridFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Produces prescription medicines, vaccines, and animal health products.
7+ YOEAdvanced degree in biological science and 7–10+ years drug development experience with majority in regulatory affairs; strong leadership, communication, and global regulatory strategy skills.
Co-pilot, ChatGPT
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Digital Twin Principal Scientist (f/m/d)
Washington, District of Columbia, United States
OnsiteFull Time
Focused Energy
Focused Energy: Develops laser-driven inertial fusion for clean energy generation.
Master’s in physics required, with Ph.D. preferred; deep IFE/ICF physics expertise; physics simulation code development and validation; strong Python, Fortran, or C++ skills; HPC and integrated systems modeling experience.
Python, Fortran, C++, HPC, Digital Twin, PIC, Monte Carlo
3mo
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Principal Research Scientist - Autonomous Systems
Basking Ridge or Annapolis Junction or Silver Spring
$146k-$234k/yr OnsiteFull Time
Peraton
Peraton: National security and mission-critical government technology services provider.
7+ YOEMinimum 7 years of experience with a PhD; strong background in AI, cybersecurity, and autonomous systems; hands-on AI development; excellent communication; US citizenship and ability to obtain/maintain a Secret clearance.
PyTorch, TensorFlow
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Principal Health Data Scientist
United States or Bowie
$132k-$176k/yr RemoteFull Time
Inovalon
Inovalon: Cloud platform for data-driven healthcare analytics and insights.
7+ YOE7+ years in healthcare/pharma data with expertise in claims/EHR, advanced SQL/Snowflake, statistical tools, problem solving, project management, and ability to work independently.
SQL, Snowflake, SAS, R, MatLab
2w
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Clinical Research & Development Associate Principal Scientist
Gaithersburg, Maryland, United States
OnsiteFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Researches, develops, and manufactures prescription medicines for major diseases.
Bachelor's degree in a scientific field and considerable pharmaceutical drug development experience, including clinical trial interpretation. Knowledge of autoimmune diseases required; advanced degree and leadership experience preferred.
Good Clinical Practice (GCP), International Council for Harmonisation (ICH), Clinical Study Reports (CSRs), Common Technical Documents (CTDs), Investigational New Drugs (INDs)
1mo
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Principal Scientist- Search
New York City or San Francisco or Los Angeles or Irvine or McLean or Washington
$212k-$394k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
8+ YOEPhD and 8+ years building and deploying production AI systems; deep expertise in information retrieval, search, NLP, RAG, knowledge graphs, LLMs; strong product sense and leadership skills.
Python, PyTorch, Hugging Face, Azure ML, Azure AI Foundry, AWS SageMaker
5d
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Data Scientist Principal
Chantilly, Virginia, United States
OnsiteFull Time
SAIC
SAICNASDAQ: SAIC: Provides government and defense clients with technology and engineering services.
5+ YOEBachelor’s plus 9 years, master’s plus 7, or doctorate/JD plus 4; equivalent experience accepted. Requires 5+ years in software engineering, data analytics, machine learning, statistics, and active Top Secret/SCI with Poly.
Microsoft Office, Artificial intelligence (AI), Machine learning (ML)
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Principal Data Scientist
Annapolis Junction, Maryland, United States
$150k-$210k/yr OnsiteFull Time
Markon
Markon: Delivers management and technical consulting services to federal agencies.
8+ YOEActive TS/SCI with polygraph, Bachelor\u0002s degree (or advanced degree in lieu of years) and 8+ years' experience, proficiency in Python, Docker, Kubernetes, ML, defensive cyber operations, and data engineering.
Python, Docker, Kubernetes, SQL, R, AWS, Jupyter Notebooks, Linux, Windows, Big Data Platform (BDP), STIGs, IAVA, Network Analysis Tools, Cisco
1mo
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Principal Data Scientist
Annapolis Junction, Maryland, United States
$150k-$210k/yr OnsiteFull Time
Markon Solutions
Markon Solutions: Provides professional program and engineering services to federal agencies.
8+ YOEActive TS/SCI with polygraph, Bachelor's +8 years (or advanced degree in lieu), proficient in Python, Docker, Kubernetes; 3+ years Defensive Cyber Ops and 3+ years ML experience; experience with databases and large-scale data workflows.
Python, Docker, Kubernetes, R, SQL, AWS, Big Data Platform (BDP), Jupyter Notebooks, Ubuntu, CentOS, RHEL, Windows
3w
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Principal Regulatory Scientist
Reston, Virginia, United States
$116k-$181k/yr OnsiteFull Time
Noblis
Noblis: Nonprofit science, technology, and strategy firm supporting government missions.
4+ YOEDoctorate in a relevant scientific discipline with ≥4 years experience (or master’s with ≥6 years); demonstrated FDA regulatory experience; strong writing, communication, analytical skills; US citizenship and active secret clearance required.
1w
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Principal Health Scientist
Washington, District of Columbia, United States
$175k-$275k/yr OnsiteFull Time
TRC Companies
TRC Companies: Engineering and environmental consulting for infrastructure and energy projects.
15+ YOERequires risk assessment experience, DABT or 15+ years in epidemiology, scientific publications, an MS or doctorate in a related field, strong technical and lay writing, and current and future U.S. work authorization.
Key Performance Indicators (KPI)
1mo
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Senior Principal Data Scientist - AI Lead (R-19518)
Vienna, Virginia, United States
HybridFull Time
Dun & Bradstreet
Dun & Bradstreet: Providing commercial data and analytics for business decisions.
10+ YOE10+ years data science/ML experience, AI/ML and NLP expertise, leadership experience, proven AI solution delivery for public sector, proficiency in Python/Java/Go and cloud platforms (AWS/Azure/GCP), Bachelor's required, Advanced degree preferred.
Python, Java, Go, AWS, Azure, GCP
6d
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Principal Data Scientist - Remote
United States or Minnetonka or Minnesota or Washington, D.C.
$113k-$193k/yr RemoteFull Time
UnitedHealth Group
UnitedHealth GroupNYSE: UNH: Provides health insurance and technology-enabled health care services.
10+ YOE10+ years designing production ML solutions; 3+ years building LLM applications; deep NLP or computer vision expertise; Python, deep learning, cloud ML, Docker/Kubernetes, and MLOps experience required.
LangChain, LangGraph, AWS, Azure, GCP, Docker, Kubernetes, Python, PyTorch, TensorFlow, MLflow, Kubeflow, TFX, Airflow, Apache Spark, Hadoop, Dask, Tableau, Power BI, LLM, GANs
2mo
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Data Scientist, Principal (DCO) Senior
Annapolis Junction, Maryland, United States
OnsiteFull Time
Gormat
Gormat: Provides cybersecurity and systems engineering services to government defense agencies
10+ YOERequires 10+ years experience (varies by degree), 3+ years Defensive Cyber Operations, 3+ years machine learning, proficiency in Python, Docker, Kubernetes, experience with end-to-end workflows, and ability to implement models into production. TS/SCI with polygraph required.
Python, Docker, Kubernetes, R, SQL, AWS (Amazon Web Services), Jupyter Notebooks, Network Analysis Tools, Big Data Platform (BDP), Linux, Ubuntu, CentOS, RHEL, Windows, Cisco CCNA, STIGs, IAVA