105 protein design jobs at 80 companies in United States
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Sr. Research Associate, Protein Design
Cambridge, Massachusetts, United States
$74k-$118k/yrOnsiteFull Time
ModernaNasdaq: MRNA: Develops and manufactures messenger RNA medicines and vaccines.
2+ YOEBachelor’s in Biochemistry/Biology/Molecular Biology with 2+ years of experience or Master’s with 1+ year; mammalian cell culture; protein expression and purification; biophysical characterization; strong communication; multi-project support.
Alta Resource Technologies: Uses synthetic biology to extract and refine critical minerals.
1+ YOEPh.D. (1–3 years) or M.S. (6+ years) in computational biology or related field; hands-on experience with protein foundation models, ML model fine-tuning, Python and modern ML frameworks, molecular modeling tools, HPC/GPU computing; US citizenship required.
Arcadia Science: Translates evolutionary biology into novel therapeutics and research tools.
3+ YOEPhD or equivalent in biochemistry/biophysics/bioengineering; 3+ yrs post-PhD; protein design and validation experience; familiarity with analysis tools; programming knowledge; autonomous, collaborative; strong communication.
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
Doctorate or Master’s with product ownership experience; or Bachelor’s with product ownership experience; or Associate with 8+ years in product ownership; strong background in ML workflows, automation, and cross-functional leadership.
Scientist, Computational Protein Design, San Francisco Bay Area, CA
Mountain View, California, United States
OnsiteFull Time
Adimab: Developing therapeutic human antibodies using a yeast-based discovery platform.
2+ YOEPhD in a relevant field, 2+ years post-PhD experience in computational protein/binder design, strong structural and energetic analysis skills, proficiency with RFAntibody, BindCraft, Protenix, strong Python skills, and publication/patent record.
Dartmouth College: Providing undergraduate and graduate education and conducting scientific research.
4+ YOEPhD or equivalent in biochemistry/molecular biology, ~4 years lab experience, expertise in recombinant protein design, expression, purification and biophysical characterization; experience with structural biology and proteomics desirable.
NovartisNew York Stock Exchange: NVS: Develops and manufactures innovative prescription medicines for patients.
5+ YOEBS/MS in biochemistry or related field with 5+ years lab experience; expertise in recombinant protein design, expression (mammalian/insect), purification (FPLC/HPLC), and biophysical characterization (SPR, DSF, ITC, LC/MS).
Merge Labs: Developing high-bandwidth non-invasive brain-computer interfaces using biotechnology.
PhD in Immunology, Bioengineering, or related field or equivalent experience; expertise in antigen processing and immune recognition; proficiency in in vitro immune assays; experience at the intersection of immunology, protein engineering, and data-driven design.
Protein Scientist, Assistant Director or Associate Director
Carlsbad, California, United States
$144k-$196k/yrOnsiteFull Time
Ionis PharmaceuticalsNASDAQ: IONS: Discovers and develops RNA-targeted medicines for serious diseases.
5+ YOEPhD in a relevant discipline, 5+ years industry experience (Assistant Director) or 8+ years (Associate Director), deep expertise in protein engineering and recombinant protein expression/purification in microbial and mammalian systems, experience with protein fusion design and characterization, strong communication and leadership.
Principal Scientist, Protein Production & Engineering
Watertown or Massachusetts
$166k-$203k/yrHybridFull Time
Disc MedicineNASDAQ: IRON: Develops treatments for patients with serious hematologic diseases.
10+ YOEPhD in relevant field,10+ years related experience with ≥5 years in biotech/pharma; extensive biologics and protein science expertise; ability to lead discovery, design and characterize proteins; strong communication and analytical skills.
3+ YOEExpertise in recombinant protein expression and purification (mammalian and bacterial), chromatographic purification, biochemical/biophysical characterization, and independent experimental design and troubleshooting.
Director / Senior Director, Computational & Protein Sciences
Cambridge, Massachusetts, United States
$250k-$290k/yrOnsiteFull Time
Stylus Medicine: Develops in vivo genetic medicines with recombinases and nanoparticles.
10+ YOEPhD in computational biology or related field with 10+ years (or Master’s with 14+ years) of industry experience; strong protein modeling/engineering experience; AI/ML for protein design; expert Python/R; cloud and workflow experience.
Design and execute experiments, troubleshoot protocols, work independently with limited supervision, act as technical point and mentor junior team members.
Neurocrine BiosciencesNASDAQ: NBIX: Develops pharmaceuticals for neurological, endocrine, and psychiatric disorders.
10+ YOEScientific leader with extensive protein/antibody engineering experience, proven team leadership, and track record advancing biologics from discovery to IND; advanced degree plus decade(s) of industry experience and expertise in construct design, expression, purification, and characterization.
Kraft HeinzNASDAQ: KHC: Manufacturer and global marketer of food and beverage products.
6+ YOEAdvanced degree in food science/biochemistry (or related) with 6+ years industry experience (PhD+6 / MS+7 / BS+8). Deep expertise in applied protein chemistry, experiment design, pilot plant scale-up, protein characterization, and patent documentation.
Principal Scientist – Antibody Discovery/Protein Design
Branford, Connecticut, United States
OnsiteFull Time
EvolveImmune Therapeutics: Developing next-generation T cell engagers for cancer immunotherapy.
5+ YOEPhD in biochemistry, computational biology, or structural biology with 5+ years antibody/biotherapeutic engineering experience; AI/ML protein design; antibody display tech; multispecific protein design; strong cross-functional collaboration.
Scientist-Principal Scientist, Protein Design & Structure
Boston, Massachusetts, United States
OnsiteFull Time
Superluminal Medicines: Accelerates small molecule drug discovery using generative AI.
2+ YOEPhD in Biochemistry/Molecular Biology/Biophysics with 2+ years (Scientist) or 5+ years (Senior Scientist) or 8+ years (Principal Scientist) of relevant experience in GPCR/membrane protein expression, purification, and characterization; strong leadership and collaboration skills.
Scientist II/Senior Scientist, Protein Sciences – Cell Binding Assays
Boston, Massachusetts, United States
$125k-$175k/yrOnsiteFull Time
Manifold Bio: Designing tissue-targeted protein therapeutics using AI and in vivo screening.
3+ YOEPhD with 3+ years (or MS with 8+ years) biotech/pharma experience, expertise in mammalian cell line engineering, FACS and cell-based assay development, antibody characterization, and independent experimental design.