59 scientific computing jobs at 40 companies in California

1mo
Save
Mark Applied
Hide
Scientific Computing Software Engineer
Northridge, California, United States
$90k-$165k/yr OnsiteFull Time
Areté
Areté: Develops advanced sensing and signal processing solutions for national security.
College degree in a scientific discipline or CS with focus on scientific computing; strong Python (numpy, scipy, pandas) and C/C++ skills; ability to obtain TS/SCI clearance; excellent communication and algorithm assessment skills.
Python, numpy, scipy, pandas, C, C++, Linux, CUDA, MPI, OpenMP
2mo
Save
Mark Applied
Hide
Associate Director, Scientific Computing and AI Engineer
South San Francisco, California, United States
$159k-$207k/yr OnsiteAll Commitments Available
Denali Therapeutics
Denali TherapeuticsNASDAQ: DNLI: Developing therapies to treat neurodegenerative and lysosomal storage diseases.
10+ YOE10-12 years in platform engineering/infrastructure with senior IC; expertise in HPC, cloud, AI/ML; IaC/CI/CD; Python; regulated biotech experience; leadership experience.
Slurm, LSF, GPU/CUDA, Cloud platforms, MLOps, LangChain, LangGraph, AutoGen, Python, Terraform, CI/CD
1mo
Save
Mark Applied
Hide
Senior AI/ML Engineer: Python & Scientific Computing
San Francisco or New York City or United States
$175k-$250k/yr HybridFull Time
Swayable
Swayable: Measures message impact and public opinion using causal AI.
5+ YOE5+ years building scientific or quantitative data‑intensive software; expertise in scientific Python stack, object‑oriented and test‑driven development, vectorized code, machine learning, and distributed/parallel computing.
Python, NumPy, SciPy, scikit-learn, Pandas, Celery, Flask, JavaScript, Vue.js, Node.js, MongoDB, GraphQL, Linux
1mo
Save
Mark Applied
Hide
Scientific Director, Computational Chemistry
San Diego, California, United States
$218k-$298k/yr OnsiteFull Time
Neurocrine Biosciences
Neurocrine BiosciencesNASDAQ: NBIX: Develops pharmaceuticals for neurological, endocrine, and psychiatric disorders.
8+ YOEAdvanced degree plus 8+–12+ years computational chemistry drug discovery experience, leadership experience, expertise in molecular modeling, SBDD, cheminformatics, AI/ML, cloud/HPC workflows, and experience integrating computational methods into multidisciplinary teams.
Knime, Schrödinger, OpenEye, MOE
3w
Save
Mark Applied
Hide
Software Engineer, Scientific Computing
Redwood City, California, United States
$130k-$190k/yr OnsiteFull Time
Vorticity
Vorticity: Developing specialized silicon to accelerate scientific computing beyond GPUs.
Bachelor's in math/physics/CS/engineering, strong Python skills, solid foundation in math/physics/CS, ability to work across abstraction levels and disciplines.
Python, CUDA
1mo
Save
Mark Applied
Hide
HPC Scientific Support Engineer
Berkeley, California, United States
$139k-$268k/yr HybridFull Time
Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory: Conducts scientific research to address global challenges.
8+ YOE8+ years related experience with a Bachelor's (CSE3) or 12+ years (CSE4); 2+ years using HPC systems; expertise in high-performance scientific computing including at least four of Linux/Unix, Fortran, C/C++, MPI, OpenMP, OpenACC, CUDA, shell scripting, Python, parallel algorithms, debuggers, performance tools, containers; strong communication and t...
Linux/Unix, Fortran, C/C++, MPI, OpenMP, OpenACC, CUDA, shell scripting, Python, debuggers, performance tools, containers, REST, JavaScript, SQL
1mo
Save
Mark Applied
Hide
Scientific and Laboratory Informatics Manager
Orlando or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or New York City or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or San Francisco or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$80k-$294k/yr OnsiteFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
6+ YOE6+ years in scientific and laboratory informatics, bachelor’s degree in life science, laboratory science, computer science or engineering, consulting experience preferred, willingness to travel up to 50% to client sites.
2w
Save
Mark Applied
Hide
Director, National Energy Research Scientific Computing Center (NERSC)
Berkeley, California, United States
$375k-$440k/yr OnsiteFull Time
Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory: Conducts multidisciplinary scientific research for the U.S. Department of Energy.
10+ YOEPh.D. and 10+ years leadership in high-performance computing, data science, or AI; strategic vision, operational and financial management, stakeholder engagement, and workforce development experience.
2mo
Save
Mark Applied
Hide
Applied Scientist, Materials Characterization and Simulations, Amazon Center for Quantum Computing
Pasadena, California, United States
$143k-$193k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Global online retail and cloud computing technology provider.
PhD in a relevant field; expertise in materials characterization and computational modeling; experience with cross-team collaboration; proficient in scientific programming.
scientific programming, computational modeling, materials characterization techniques
1w
Save
Mark Applied
Hide
Research Software Engineer I - Center for AI and Research Computing (AIRC)
La Jolla, California, United States
$33-$38/hr OnsiteFull Time
Salk Institute
Salk Institute: Conducts biological research to solve global health challenges.
0+ YOEEarly-career software engineer with full-stack ability in Python and another language, Git experience, Linux familiarity, demonstrated coding portfolio, and interest in scientific collaboration and HPC.
Python, Claude Code, Git, SLURM, Claude API, Docker, Kubernetes, AWS, GCP, React, Svelte, Vue, FastAPI, Django, GitHub, Linux/Unix, CI/CD
1w
Save
Mark Applied
Hide
Postdoctoral Appointee - Computational Mechanics, Onsite
Livermore, California, United States
OnsiteFull Time
Sandia National Laboratories
Sandia National Laboratories: Federal research and development laboratory for national security.
PhD in engineering or related field, proficiency in computational mechanics, scientific computing and software development, ability to obtain DOE Q clearance (U.S. citizenship required).
C++, Python
1w
Save
Mark Applied
Hide
Postdoctoral Appointee - Computational Mechanics, Onsite
Livermore, California, United States
OnsiteFull Time, Temporary
Sandia National Laboratories
Sandia National Laboratories: Conducts science and engineering research for national security.
PhD in mechanical/civil/aerospace engineering or related, proficiency in computational mechanics, scientific computing and software development, ability to obtain DOE Q clearance (U.S. citizenship required).
C++, Python
2w
Save
Mark Applied
Hide
Research Scientist, Life Sciences (Computational)
San Francisco, California, United States
$300k-$320k/yr HybridFull Time
Anthropic
Anthropic: Developing safe and reliable artificial intelligence systems.
PhD or equivalent industry research experience in computational biology or related field; track record of end-to-end computational biology research; proficiency with Linux, cloud compute, and scientific programming; strong communication with biologists and ML researchers.
Claude, Linux
5d
Save
Mark Applied
Hide
Senior Manager, Research Informatics
Redwood City, California, United States
$164k-$205k/yr HybridFull Time
Revolution Medicines
Revolution MedicinesNASDAQ: RVMD: Developing precision oncology therapies for RAS-addicted cancers
7+ YOEBachelor's in scientific/computational field,7+ years leading research informatics or scientific applications,experience with assay management platforms,SQL and Python proficiency,people leadership and program management skills.
Genedata Screener, Benchling, Genedata Expressionist, D360, Mosaic, IDBS ActivityBase, Revvity Signals, SQL, Python
1w
Save
Mark Applied
Hide
Computer Systems Manager
San Diego, California, United States
$100k-$183k/yr OnsiteFull Time
General Atomics Aeronautical Systems
General Atomics Aeronautical Systems: Designs and manufactures unmanned aircraft and radar systems.
9+ YOE5+ MgmtBachelor's in computer science (or equivalent experience),9+ years IT experience,5+ years management,Linux and web services experience,scientific data management,project management and strong communication;US citizenship required.
Linux, Web Services
1mo
Save
Mark Applied
Hide
HPC Systems Engineer, Modeling & Simulation
Costa Mesa, California, United States
$132k-$198k/yr OnsiteFull Time
Anduril Industries
Anduril Industries: Defense technology building autonomous military hardware and software.
5+ YOE5+ years administering Linux/Unix in HPC or scientific computing; hands-on cluster, storage, and scientific code support; Bash/Python scripting; experience with MPI/OpenMP, CMake, compilers, filesystems, and secure computing; bachelor's degree in a technical field; ability to obtain US security clearance.
Linux, Unix, Windows, Bash, Python, CTH, ALE3D, Sierra, ParaView, Cubit, VisIt, CMake, compilers, MPI, OpenMPI, OpenMP, NFS, NAS, TCP/IP, Slurm
4d
Save
Mark Applied
Hide
Member of Technical Staff - Applied Computational Biologist
New York City or San Francisco
OnsiteFull Time
Valthos
Valthos: Develops AI systems to identify biological threats and design countermeasures.
Extensive computational biology research experience, strong scientific communication, ability to analyze biological data, proficiency in Python, and ability to work on-site in New York City or San Francisco.
Python
2d
Save
Mark Applied
Hide
Applied AI Scientist, Technology Partnerships (Senior/Principal)
San Francisco, California, United States
$200k-$300k/yr OnsiteFull Time
Sygaldry
Sygaldry: Building quantum-accelerated servers for efficient AI model training.
Advanced computational background (MS/PhD preferred) with strong Python and scientific computing, generative modeling and benchmarking experience, ability to prototype and validate methods in partner domains.
Python
2mo
Save
Mark Applied
Hide
Junior/Assistant Specialist - Energy Decomposition Analysis (EDA) / M. Head-Gordon Group - Dept. of Chemistry
Berkeley, California, United States
$57k-$66k/yr OnsitePart Time
University of California
University of California: A public research university system providing education and healthcare.
Bachelor's degree required; coding in Python and C++; experience with data analysis and scientific computing; authorized to work in the U.S.; no visa sponsorship.
Python, C++, Microsoft Word, Microsoft Excel, Microsoft PowerPoint
2mo
Save
Mark Applied
Hide
Clinical Research Associate - Sponsor Dedicated
Overland Park or Carlsbad
$72k-$189k/yr OnsiteFull Time
IQVIA
IQVIANYSE: IQV: Provides clinical research and data analytics for pharmaceutical companies.
Bachelor's degree preferred in scientific field or health care; GCP/ICH knowledge; good communication and time management; computer skills.
Microsoft Word, Microsoft Excel, Microsoft PowerPoint, Laptop, iPhone, iPad