15 senior fastapi developer jobs at 10 companies in Lancaster, CA

1mo
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Senior AI Engineer
United States or New York City or Palm Beach or Los Angeles or Miami or Greenwich or Westchester County or The Hamptons or San Francisco or Manhattan
$190k-$250k/yr RemoteFull Time
Atria Health Institute
Atria Health Institute: Membership-based concierge practice providing preventive, precision-based medical care.
4+ YOE4+ years building and operating LLM-powered production ML systems, strong Python, backend framework experience (FastAPI/Flask), LLM orchestration and retrieval design, Snowflake/dbt/Dagster/Airflow familiarity, evaluation systems, HIPAA/PHI knowledge, and strong written communication.
Python, FastAPI, Flask, Snowflake, dbt, Dagster, Airflow, vLLM, Triton, TGI, SGLang, LOINC, SNOMED CT, ICD-10, RxNorm, FHIR, HL7
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Senior Software Engineer | Remote
Los Angeles or United States
RemoteFull Time
TubeScience
TubeScience: Data-driven performance video production for social media advertising.
Senior full-stack engineer to lead frontend tooling, backend services, and cloud infrastructure for production AI integrations; strong JavaScript and Python skills, low-level language experience, media pipeline knowledge, observability and distributed systems expertise.
JavaScript, React, Vue, Angular, Python, C, C++, Rust, Zig, Next.js, FastAPI, Django, Flask, Docker, Kubernetes, PostgreSQL, MongoDB, Redis, Temporal, Airflow, Dagster, Kafka, RabbitMQ, ffmpeg, AWS, GCP, Azure
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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Senior Software Engineer - AI, CoCounsel International
Eagan or Frisco or New York City or Ann Arbor or San Francisco or Los Angeles or Irvine or McLean or Washington
$110k-$204k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
4+ YOE4+ years backend engineering experience with Python, FastAPI, PostgreSQL, AWS; production agentic AI and LLM integration experience; strong debugging, architecture, and collaboration skills.
Python, FastAPI, PostgreSQL, AWS, OpenAI, Anthropic
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Principal Engineer, CoCounsel
Eagan or Frisco or New York City or Toronto or Ann Arbor or San Francisco or Los Angeles or Irvine or McLean or Washington
$159k-$295k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
Bachelor's degree (or equivalent) in CS or CE, deep Python and distributed systems experience, hands-on AI/LLM and agent experience, FastAPI/PostgreSQL/AWS familiarity, identity/IAM (SAML, OIDC, OAuth 2.0) expertise, strong communication.
Python, FastAPI, PostgreSQL, AWS, SSO, SAML, OIDC, OAuth 2.0, RBAC, ABAC, Anthropic, OpenAI, LLMs, MCP servers, vector databases, embeddings, semantic search
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Staff Software Engineer – AI Platform
Eagan or Frisco or Brooklyn or Toronto or Ann Arbor or New York City or San Francisco or Los Angeles or Irvine or McLean or Washington
$127k-$273k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
5+ YOE5+ years building scalable cloud applications, deep Python and FastAPI experience, PostgreSQL and AWS experience, familiarity with LLMs/AI systems, strong distributed-systems and architecture skills.
Python, FastAPI, PostgreSQL, AWS, Vercel, OpenAI, Anthropic
3w
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Sr. Full Stack Engineer
Tempe or Burbank
$135k-$163k/yr HybridFull Time
Entertainment Partners: Provides payroll and workforce management for entertainment productions.
6+ YOE6+ years software engineering experience, strong Python (FastAPI), React.js/TypeScript, API and database expertise, CI/CD and cloud experience, LLM/AI integration, bachelor's degree or equivalent.
Python, FastAPI, React.js, TypeScript, PostgreSQL, MySQL, MongoDB, ORMs, GitHub Actions, Jenkins, Microsoft Azure DevOps, Docker, Kubernetes, AWS, Azure, OCI, OpenAI, Anthropic/Claude, LangChain, LangGraph, pgvector, Pinecone, Weaviate, WebSockets, SSE, JWT, OAuth2
2w
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Senior Data Engineer
New York City or San Francisco or Los Angeles
$165k-$220k/yr HybridFull Time
Regard
Regard: A healthcare-focused software building AI-powered documentation tools to improve care delivery and clinician workflow.
5+ YOE5+ years data engineering experience, 3+ years PySpark and public cloud (AWS S3/EMR), strong Python and SQL, BS in CS/related or equivalent, experience with data modeling, pipelines, and on-call support.
S3, Apache Iceberg, EMR, PySpark, Dagster, Kubernetes, Clickhouse, PostgreSQL, FastAPI, Metabase, Python, SQL
2mo
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Senior AI Engineering
Pasadena or New York City or Houston
$150k-$275k/yr OnsiteFull Time
East West Bank
East West BankNASDAQ: EWBC: Provides commercial and consumer banking services across US and Asia.
10+ YOE10+ years in software/AI engineering, experience delivering production LLM/AI solutions, strong Python and cloud (Azure) skills, experience with ML/LLM frameworks, and fintech/regulatory domain knowledge.
Python, FastAPI, Flask, Azure OpenAI, Azure ML, Databricks, ADLS, Azure AI Search, OpenAI ChatGPT, OpenAI Codex, Anthropic Claude, Google Gemini, Microsoft Copilot, AWS Bedrock, Llama, Mistral, LangChain, LlamaIndex, Semantic Kernel, vector databases, model registries, CI/CD, MLOps, LLMOps
2w
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Staff Software Engineer, Frameworks
Mountain View or Los Angeles or San Francisco
$210k-$250k/yr HybridFull Time
Commure
Commure: AI-powered software platform for healthcare workflow and administrative automation.
8+ YOE8+ years software engineering experience designing and operating secure, scalable authentication/authorization and distributed backend systems; experience with Kubernetes and cloud-native infrastructure; strong technical leadership and mentorship.
OAuth 2.0, OIDC, JWT, AWS Cognito, Python, FastAPI, Pydantic, PostgreSQL, Go, Kubernetes
2mo
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Senior Platform Engineer, Data & AI Infrastructure
Durham or New York City or Los Angeles or Phoenix
$140k-$160k/yr HybridFull Time
McKinney
McKinney: Provides strategic advertising and creative marketing services to brands.
4+ YOE4+ years of professional software engineering with backend focus; strong Python, cloud, and data tooling; experience with AI/LLM integration and security best practices.
Terraform, GitOps, Snowflake, Fivetran, DBT, Python, FastAPI, Docker, Kubernetes, OpenAI, Anthropic, Google Gemini, BigQuery, Dataform, Cloud Run, Compute Engine, Secret Manager, Artifact Registry, Cloud Build, Cloud Monitoring, IAM, Secret Management, ECR, CodePipeline, CI/CD
2w
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Full Stack Engineer
Los Angeles, California, United States
$89k-$136k/yr RemoteFull Time
Publicis Groupe
Publicis GroupeEuronext Paris: PUB: Global advertising and digital transformation agency holding.
8+ YOE8+ years full‑stack experience; expert in Node.js, JavaScript, TypeScript, React; experience with microservices, gRPC, relational databases, Redis, AWS, Docker/Kubernetes; US work authorization required.
TypeScript, gRPC, React, GoLang, Redis, Memcached, MariaDB, MySQL, Postgres, RESTful APIs, Node.js, JavaScript, StoryBook, CSS/SASS, AWS, Docker, Kubernetes, GraphQL, Flask, FastAPI, Kafka, Python, Figma
3w
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Staff Software Engineer - Biller Workflows
Mountain View or Los Angeles or New York City or San Francisco
$210k-$275k/yr HybridFull Time
Commure
Commure: AI-powered software platform for healthcare workflow and administrative automation.
8+ YOE8+ years building large-scale full-stack applications; org-wide frontend leadership; deep React/TypeScript, Python, and PostgreSQL expertise; API and data-layer design; strong debugging, observability, and communication skills.
React, TypeScript, Python, FastAPI, PostgreSQL, StarRocks, ClickHouse, Druid, EDI X12, LLM, CI/CD
2w
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Principal Engineer
Eagan or Frisco or New York City or Toronto or Ann Arbor or San Francisco or Los Angeles or Irvine or McLean or Washington
$159k-$295k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
Expertise in identity and access management, distributed systems, and AI/LLM integration; deep Python experience; cloud (AWS) and relational DB (PostgreSQL); strong communication and architecture ownership skills.
Python, FastAPI, PostgreSQL, AWS, Okta, Auth0, Entra ID/Azure AD, AWS Cognito, Anthropic, OpenAI, vector databases, SAML, OIDC, OAuth 2.0, RBAC/ABAC, MCP, LLMs
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Agentic AI Architect - Intelligence Engineering (West)
Denver or East Bay or Los Angeles or Orange County or Phoenix or Portland or Salt Lake City or San Diego or San Francisco or Seattle or Silicon Valley
$108k-$237k/yr HybridFull Time
Slalom
Slalom: Provides business and technology consulting and software engineering services.
5+ YOE5+ years software engineering experience with 2+ years on generative/agentic AI, multi-agent system design, RAG architectures, cloud AI platform deployment, Python proficiency, and strong communication skills.
Python, FastAPI, Flask, Lang Graph, Strands Agents SDK, OpenAI Agents SDK, Google ADK, LangSmith, Model Context Protocol (MCP), AWS Bedrock, Azure AI Foundry, OpenAI Service, GCP Vertex AI, Gemini, Databricks, Claude Code, Cursor, Kiro, RAGAS, DeepEval