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81 senior fastapi developer jobs at 55 companies in Vacaville, CA

3mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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2mo
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Senior Software Engineer, App
Cambridge or San Francisco
$144k-$240k/yr HybridFull Time
Lila Sciences
Lila Sciences: Develops an AI platform for autonomous scientific research and discovery.
5+ YOEBachelor’s or Master’s in CS/Engineering; 5-8+ years backend/full-stack exp; React, TypeScript, FastAPI, Python; AWS, Kubernetes; AI tooling; strong collaboration.
React, TypeScript, Nx, Tailwind, FastAPI, Python, Pydantic, SQL, NoSQL, AWS, Kubernetes, Terraform, GitHub Actions
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2mo
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Senior Backend Engineer
San Francisco, California, United States
$175k-$275k/yr OnsiteFull Time
Hedra
Hedra: Builds artificial intelligence models for character-driven video generation.
5+ YOE5+ years backend development with Python, FastAPI/Pydantic; Kubernetes/EKS; relational databases; AWS stack; building scalable services.
Python, FastAPI, Pydantic, Kubernetes, EKS, PostgreSQL, Redis, S3, DynamoDB, AWS
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1mo
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Senior Software Engineer - Python
Toronto or San Francisco
$130k-$225k/yr RemoteFull Time
Veeva Systems
Veeva SystemsNYSE: VEEV: Cloud-based software solutions for the global life sciences industry.
5+ YOE5+ years software development with production-level Python, enterprise SaaS/scale experience, proficiency with Python, Git, FastAPI, Pydantic, strong communication and mentorship skills, and unrestricted right to work in the U.S.
Python, Git, FastAPI, Pydantic
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2mo
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Senior Software Engineer
San Francisco, California, United States
$146k-$235k/yr HybridFull Time
DocuSign
DocuSignNASDAQ: DOCU: Provides electronic signature and agreement management software solutions.
8+ YOEBachelor's in CS or STEM with 8+ years of software engineering experience; full-stack with Java/JavaScript-TS, React; experience with Oracle Fusion Cloud APIs, OIC, Python, AI/ML, cloud-native tech, and CI/CD.
Java, JavaScript, TypeScript, React, OIC, VBCS, APEX, Groovy, PL/SQL, Oracle Fusion Cloud APIs, Python, Django, FastAPI, REST, SOAP, JSON/XML, Docker, Kubernetes, AWS, Azure, Oracle OCI, Jira, Confluence, GitHub Co-Pilot, LLMs, MLOps, RAG
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1mo
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Senior AI Engineer
United States or New York City or Palm Beach or Los Angeles or Miami or Greenwich or Westchester County or The Hamptons or San Francisco or Manhattan
$190k-$250k/yr RemoteFull Time
Atria Health Institute
Atria Health Institute: Membership-based concierge practice providing preventive, precision-based medical care.
4+ YOE4+ years building and operating LLM-powered production ML systems, strong Python, backend framework experience (FastAPI/Flask), LLM orchestration and retrieval design, Snowflake/dbt/Dagster/Airflow familiarity, evaluation systems, HIPAA/PHI knowledge, and strong written communication.
Python, FastAPI, Flask, Snowflake, dbt, Dagster, Airflow, vLLM, Triton, TGI, SGLang, LOINC, SNOMED CT, ICD-10, RxNorm, FHIR, HL7
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3mo
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Senior Fullstack Engineer, Solve
Austin or Madison or San Francisco
$145k-$217k/yr HybridFull Time
Zendesk
Zendesk: Provides cloud-based software for customer service and support.
3+ YOE3+ years of production software experience; backend-first with APIs, async systems, integrations, and real-time systems; ownership of features end-to-end; experience with real-time or event-driven tech such as WebSockets/WebRTC.
Python, FastAPI, React, TypeScript, WebRTC, Redis, MongoDB, LLM / speech
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2mo
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Staff Platform Engineer (Pacific Time Zone)
San Francisco, California, United States
$225k-$275k/yr HybridFull Time
Komodo Health
Komodo Health: Provides AI-driven healthcare data and patient journey analytics software.
Senior backend engineer with platform and control-plane experience; strong Python (FastAPI) and AWS; multi-tenant SaaS; focus on observability, reliability, and developer productivity.
Python, FastAPI, AWS, Snowflake, Airflow, Spark, RBAC, API design, KMC/PSS
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1mo
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Senior Software Engineer, Full-Stack
San Francisco, California, United States
$170k-$230k/yr HybridFull Time
Roger Healthcare
Roger Healthcare: AI clinical documentation platform for home health clinicians.
7+ YOE7+ years software engineering experience with deep backend expertise; experience with distributed systems, production LLM/Generative AI systems, FastAPI, MongoDB/Postgres, Docker, and AWS; strong communication and product mindset.
FastAPI, MongoDB, Postgres, Docker, AWS, LLMs, Generative AI
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Senior Software Engineer, Engine & Distributed Systems
San Francisco or New York City
$220k-$240k/yr HybridFull Time
StackAI
StackAI: Build and deploy custom AI agents without writing code.
5+ YOE5+ years building backend distributed systems; experience with durable execution/workflow orchestration (Temporal, Cadence, Airflow), strong Python and FastAPI skills, Postgres familiarity, concurrency, fault tolerance, and recovery.
Temporal, Cadence, Airflow, Python, FastAPI, Postgres, PydanticAI, LangGraph
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Senior Software Engineer - Full Stack, Technical Lead
San Francisco, California, United States
$200k-$250k/yr HybridFull Time
Baton
BatonNYSE: R: Builds AI software to automate and optimize supply chains.
5+ YOE5+ years full-stack experience; advanced Python; frontend with React and TypeScript; backend experience with GraphQL/FastAPI; Postgres and AWS familiarity; proven technical project leadership and mentorship.
Python 3, GraphQL, FastAPI, React, TypeScript, Postgres, AWS
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1d
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Copy of Senior Software Engineer, Identity Graph
San Francisco, California, United States
$230k-$340k/yr HybridFull Time
Baselayer
Baselayer: AI-powered business identity and risk verification platform.
Proven experience shipping end-to-end product features (ingestion→storage→API), strong async Python, deep Postgres expertise, FastAPI/OpenAPI experience, and multi-tenant API and schema ownership.
Postgres, Python, FastAPI, OpenAPI, GCP, Cloud Run, Cloud Tasks, Cloud SQL
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4w
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Senior Software Engineer, W&B Agent - W&B
Livingston or New York City or San Francisco or Sunnyvale or Bellevue
$182k-$242k/yr OnsiteFull Time
CoreWeave
CoreWeaveNASDAQ: CRWV: Specialized cloud infrastructure provider for high-performance AI workloads.
4+ YOE4+ years full‑stack experience with Python backend and React/TypeScript frontend; experience with FastAPI, Kubernetes, distributed systems, observability, and MySQL; security- and performance-minded.
Python, FastAPI, Kubernetes, React, TypeScript, Datadog, Weave tracing, MySQL, WebSockets, server-sent events
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2mo
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Member of Technical Staff - Senior Software Engineer
San Francisco, California, United States
$150k-$300k/yr OnsiteFull Time
Patronus AI
Patronus AI: Provides automated evaluation and simulation infrastructure for AI systems.
4+ YOE4+ years engineering experience; full-stack ownership from frontend to backend; strong React/TypeScript, API and services design, Python/FastAPI, Go, and Postgres experience; familiarity with Kubernetes and agent/LLM integrations.
React, TypeScript, Next.js, Python, FastAPI, Postgres, Go, Kubernetes, Claude Code, Codex, Cursor, Playwright, Selenium
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2mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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3d
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Senior Backend Engineer
San Francisco, California, United States
$110k-$200k/yr OnsiteFull Time
Clera
Clera: AI talent agent matching professionals with high-growth startup roles
5+ YOE5+ years backend experience, proficiency in Python, FastAPI, SQL, testing with pytest, experience designing data architectures and shipping production systems, familiarity with AI-assisted coding tools.
Python, FastAPI, pytest, Claude Code, Codex, OpenCode, SQL, AWS
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1w
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Senior Software Engineer - AI, CoCounsel International
Eagan or Frisco or New York City or Ann Arbor or San Francisco or Los Angeles or Irvine or McLean or Washington
$110k-$204k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
4+ YOE4+ years backend engineering experience with Python, FastAPI, PostgreSQL, AWS; production agentic AI and LLM integration experience; strong debugging, architecture, and collaboration skills.
Python, FastAPI, PostgreSQL, AWS, OpenAI, Anthropic
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1mo
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Founding Engineer
San Francisco, California, United States
$120k-$150k/yr OnsiteFull Time
Avent Industrial
Avent Industrial: AI-powered operating system for industrial supply chains.
Experienced engineer to build core systems for quoting, procurement, and decision-making; systems thinking, high ownership, speed with judgment; familiarity with Next.js, TypeScript, Python/FastAPI, and PostgreSQL.
Next.js, TypeScript, Python, FastAPI, PostgreSQL
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2mo
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Senior Software Engineer
San Francisco, California, United States
$165k-$266k/yr HybridFull Time
DocuSign
DocuSignNASDAQ: DOCU: Provider of e-signature and intelligent agreement management software.
8+ YOEBachelor's in CS/STEM and 8+ years software engineering experience; expertise with Java, JavaScript/TypeScript, React, APIs, integrations, Python, cloud, CI/CD and AI frameworks; strong communication and problem solving.
Java, JavaScript/TypeScript, React, OIC (Oracle Integration Cloud), VBCS, APEX, Groovy, PL/SQL, Oracle Fusion Cloud APIs, Python, Django, FastAPI, REST, SOAP, JSON/XML, LLMs, RAG, MLOps, GitHub Co-Pilot, SQL, Docker, Kubernetes, CI/CD, AWS, Azure, Oracle OCI, Jira, Confluence
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2mo
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Senior Software Engineer
New York City or Boston or San Francisco
$160k-$200k/yr RemoteFull Time
Roebling
Roebling: AI-native capital project planning platform for industrial infrastructure.
5+ YOE5–7 years shipping production software (startup scaling experience preferred), strong engineering fundamentals, end-to-end product instincts, and familiarity with AI-native agent tooling (Claude Code, Cursor) preferred.
React, Next.js, Redux, TailwindCSS, Vercel, FastAPI, PostgreSQL, Pydantic, Supabase, Claude Code, Cursor, Anthropic, Google model APIs, LangChain, LangGraph
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