23 senior python developer jobs at 17 companies in Cayce, SC
🚀PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yrOn-SiteFull Time
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yrHybridFull Time
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
AMC Health: Provides remote patient monitoring and virtual care technology.
7+ YOE7+ years building production backend systems, strong Python, cloud/distributed systems experience, hands-on LLM/generative AI, ML lifecycle proficiency, and disciplined work in regulated environments.
Rolls-Royce Power Systems: Designs and manufactures high-performance engines and power systems.
5+ YOEBachelor's in engineering or CS with 5 years controls experience (or 9 years w/o degree). Experience with data acquisition (iTest), VCL, Python, test automation protocols, SAP, database work; U.S. work authorization required.
iTest, VCL, Python, Uniplot, EtherCAT, AK Protocol, SCPI, CAN, MODBUS, SAP, Microsoft Office
Rolls-RoyceLondon Stock Exchange: RR: Manufacturer of aircraft engines and industrial power systems.
5+ YOEBachelor's in ME/CS/EE plus 5 years industrial controls experience (or 9 years experience), experience with data acquisition (iTest), VCL/Python scripting, controls/automation protocols, SAP, database work, strong troubleshooting and analytical skills.
iTest, VCL, Python, Uniplot, EtherCAT, AK Protocol, SCPI, CAN, MODBUS, SAP, Microsoft Office
Genesis Healthcare: Provides primary and preventive medical care to underserved communities.
5+ YOE5-10 years SQL development experience with strong T-SQL and Microsoft SQL Server skills, SQL Server Agent, ETL knowledge, exposure to Azure SQL/Snowflake, Python/PowerShell preferred, strong analytical and troubleshooting skills. Bachelor's degree required.
T-SQL, Microsoft SQL Server, SQL Server Agent, Python, PowerShell, Azure SQL, Snowflake, ChatGPT, Copilot Studio
Zeus: Global leader in polymer extrusion and catheter design manufacturing
6+ YOEBachelor's in CS or related, 6+ years in software/AI engineering, strong Python and API skills, hands-on experience with LLMs, RAG, prompt engineering, vector search/databases, LangChain-like frameworks, cloud platforms, and CI/CD.
Omaha or Saint Louis Park or Denver or Englewood or Orlando or Kansas City or Albuquerque or Portland or Salem or Pittsburgh or Austin or Dallas or Fort Worth or San Antonio or Vienna or Olympia or Columbia or St. Paul or Harrisburg or Pennington or Woodcliff Lake or Phoenix or Folsom
OnsiteFull Time
HDR: Global provider of engineering, architecture, environmental and construction services.
5+ YOE5+ years in virtualization/infrastructure/private cloud operations; hands-on VCF, SDDC Manager, vSphere administration; vSAN/NSX knowledge; scripting/automation with PowerCLI, Python, or Ansible; lifecycle ops and production troubleshooting.
Denver or Greenville or Roanoke or Charleston or Raleigh or San Antonio or Des Moines or Richmond or Charlottesville or St. Louis or Cedar Rapids or Waco or Canonsburg or Greensboro or Little Rock or Lubbock or Kansas City or Knoxville or Omaha or Charleston or Wilmington or Dallas or Albuquerque or Charlotte or Waynesboro or Lincoln or Columbia
$116k-$140k/yrHybridFull Time
Segra: Provider of fiber-based connectivity and managed technology solutions for businesses.
10+ YOE10+ years related experience, bachelor’s degree or equivalent, strong security and telecom protocol knowledge, scripting (Python or PowerShell), SIEM/Splunk, IAM, cloud security (AWS/Azure), IaC/automation, incident response, and compliance frameworks (NIST/ISO).
Savannah River National Laboratory: Provides research and development for nuclear security and environmental cleanup.
PhD in geophysics or related field, extensive ERT/SIP field and inversion experience, expertise in numerical modeling and data processing, publication record, leadership experience, and U.S. citizenship to obtain security clearance.
MicroTech: Provides IT, network, and cybersecurity solutions for government agencies.
8+ YOEProvides Tier 2/3 technical support and software integration; develops and maintains software (C++, C#, Java, .NET, Python); requires DoD 8140 DCWF 411 (Advanced), CCE-V or equivalent, active Secret clearance, and 8+ years of software development/engineering experience (or equivalent).
State of South Carolina: Providing government administration and public services for South Carolina.
Master's in a health-related field required; conduct literature reviews, manage and analyze quantitative data, provide biostatistics/statistical consulting, and proficiency with SAS, R, or Python and quantitative/AI/ML methods.
Savannah River Mission Completion: Manages liquid waste operations at Savannah River Site
Develop and lead environmental performance assessments for waste disposal and tank closure; familiarity with PORFLOW and GoldSim; experience with numerical modeling (MATLAB, Python); strong written and verbal communication.
Credence: Provides technology and management solutions to federal government agencies.
10+ YOETop Secret clearance (TS/SCI) required; Bachelor's in a quantitative field with 10 years' experience; 3–5 years AI/ML development; proficiency with Python and SQL; formal intelligence analysis training and strong communication skills.