188 senior python developer jobs at 115 companies in South Carolina

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
1mo
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Senior API Engineer (Python / AWS)
Fort Mill or Charlotte or Austin
$106k-$177k/yr HybridFull Time
LPL Financial
LPL FinancialNASDAQ: LPLA: Provides wealth management and brokerage services to financial advisors.
7+ YOE7+ years in software/API/cloud development; Python API development; AWS Lambda/API Gateway; Terraform; CI/CD; production support.
Python, AWS, Terraform, OAuth2, JWT, IAM, Amazon API Gateway, AWS Lambda, CloudWatch, OpenTelemetry
1mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
2mo
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Senior Software Engineer I
Fort Mill or Tempe
HybridFull Time
Shutterfly
Shutterfly: Manufacturer and retailer of personalized photo products and professional photography services.
6+ YOE6+ years in application development; Java, Spring Boot, Python; 3+ years AWS; driven to build scalable systems; experience with Agile and CI/CD; mentorship capabilities.
Java, Spring Boot, Python, AWS, React, Angular, RabbitMQ, GraphQL, Terraform, REST
1mo
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Senior AI Engineer - Agentic Systems
Atlanta or Raleigh-Durham or Phoenix or Tucson or Orlando or Nashville or Jacksonville or Houston or Greenville or Dallas or Tampa or Fort Lauderdale or Charlotte or Austin
OnsiteFull Time
DPR Construction
DPR Construction: General contractor for complex technical and sustainable construction projects.
6+ YOE6+ years production software engineering; 2+ years building LLM-powered systems; strong Python; LangChain/LangGraph experience; retrieval architectures; cloud data platforms; strong communication.
Python, LangChain, LangGraph, Snowflake Cortex, vector search
2w
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Senior Backend Developer
Tennessee or Idaho or Arkansas or Nebraska or Louisiana or Missouri or Texas or Indiana or Nevada or Kentucky or Mississippi or Florida or South Carolina or West Virginia or New Mexico or North Carolina or Oklahoma or South Dakota or Alabama or Utah or Kansas or Iowa or Pennsylvania or Michigan or Wisconsin or Georgia or Montana or Arizona or North Dakota or Wyoming
RemoteFull Time
Sedgwick
Sedgwick: Provides global insurance claims management and risk services.
7+ YOEBachelor's in CS/Engineering, 7+ years backend development, proficiency in Java/C#/Python/Node.js, REST/microservices, legacy integrations, SQL/NoSQL, Docker/Kubernetes, Kafka/RabbitMQ, API security and observability.
Java, C#, Python, Node.js, SOAP, XML, JSON, SQL Server, Oracle, PostgreSQL, Redis, Docker, Kubernetes, Kafka, RabbitMQ, OpenAPI/Swagger, JDBC/ODBC, OAuth2, JWT, mutual TLS, SAML, API gateways, service meshes, message queues
1mo
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Senior Software Engineer
New York City or Arizona or California or Colorado or Connecticut or Florida or Georgia or Maine or Maryland or Massachusetts or Michigan or Minnesota or New Jersey or New York or North Carolina or Oregon or Rhode Island or South Carolina or Tennessee or Texas or Virginia or Utah or Wisconsin
$165k-$185k/yr RemoteFull Time
Electric
Electric: Provides automated IT management and security services for businesses.
8+ YOE8+ years backend experience with modern Python stack, leadership experience, proficiency in Postgres/SQLAlchemy, AWS, Terraform, FastAPI, React/TypeScript, observability, and familiarity with AI-assisted development.
Python, FastAPI, Pydantic, PostgreSQL, SQLAlchemy, Alembic, Temporal, Redis, AWS RDS, AWS S3, AWS SQS, AWS DynamoDB, AWS ECS, AWS IAM, Terraform, React, TypeScript, Claude Code
1w
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Senior Backend Software Engineer
Arkansas or California or Colorado or District of Columbia or Florida or Illinois or Massachusetts or Maryland or Maine or Michigan or New Jersey or Ohio or Pennsylvania or South Carolina or Texas or Utah or Virginia or Washington
$165k-$195k/yr RemoteFull Time
SITE Technologies
SITE Technologies: Provides AI-powered property condition assessments and management software.
5+ YOE5+ years backend development experience with Python and FastAPI, strong backend architecture, relational modeling, AWS services, Docker, CI/CD, and cross-team communication.
Python, FastAPI, PostgreSQL, SQLAlchemy, Alembic, Flyway, AWS, ECS, Lambda, RDS, S3, IAM, Docker, Git, CI/CD, GitHub Actions, AWS CodePipeline, Claude Code, Cursor, Terraform, Terragrunt, Datadog, Sentry, LangGraph, Claude Code SDK, Amazon Bedrock
2d
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Senior Application Developer
Pennsylvania or Maryland or Washington or North Carolina or Louisiana or Kentucky or Kansas or Indiana or Illinois or Georgia or Iowa or Florida or Colorado or California or Delaware or Connecticut or Arkansas or Arizona or Alabama or Alaska or Nevada or Vermont or Tennessee or Idaho or Oklahoma or Hawaii or Mississippi or Utah or New Hampshire or New Mexico or Wyoming or North Dakota or South Dakota or Rhode Island or West Virginia or Montana or Texas or Ohio or New Jersey or Oregon or South Carolina or Missouri or Virginia or Massachusetts or Nebraska or Minnesota or Michigan or Wisconsin or New York or Maine or District of Columbia
$86k-$139k/yr RemoteFull Time
Highmark Health
Highmark Health: Provides health insurance and integrated medical care services.
5+ YOE5+ years in scalable system design and modern programming languages (.NET, Angular, SQL, Java, Python, C#, JavaScript); experience defining system architectures, web services (REST/HTTPS/JSON); healthcare IT preferred.
.NET, Angular, SQL, Java, Python, C#, JavaScript, REST, HTTPS, JSON, HTML5, CSS, Google Cloud Platform (GCP), Amazon Web Services (AWS), MSSQL, Windows Server
1mo
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Senior Software Engineer Test
California or New Jersey or New York or Washington or Hawaii or Alaska or Maryland or Connecticut or Rhode Island or Massachusetts or Nevada or Oregon or Arizona or Colorado or Wyoming or Texas or North Dakota or Minnesota or Missouri or Illinois or Wisconsin or Florida or Georgia or Michigan or Ohio or Virginia or Pennsylvania or Delaware or Vermont or New Hampshire or Maine or Utah or Idaho or Montana or New Mexico or South Dakota or Nebraska or Kansas or Oklahoma or Iowa or Arkansas or Louisiana or Mississippi or Alabama or Tennessee or Kentucky or Indiana or South Carolina or North Carolina or West Virginia or United States
$94k-$179k/yr RemoteFull Time
Mercury Insurance
Mercury InsuranceNYSE: MCY: Provider of personal and commercial insurance coverage.
5+ YOEBachelor's in CS or related (or equivalent experience), 5+ years industry experience, 3+ years Java/Python and automation/framework development, CI/CD, containerization, cloud, performance and API testing experience.
Jenkins, GitHub, JMeter, LoadRunner, Selenium, TestNG, JUnit, Appium, Docker, Kubernetes, AWS, Google Cloud, Azure, Postman, SoapUI, Curl, Insomnia, Java, Python, JavaScript
1mo
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Senior Software Engineer
Greenville, South Carolina, United States
OnsiteFull Time
TRULEO: AI-powered workflow and analytics platform for law enforcement
7+ YOE7+ years software engineering; production experience with React, TypeScript, Node.js, PostgreSQL; Python, ML/MLOps; cloud and containerized deployments; able to work onsite in Greenville, SC and pass CJIS background check.
React, TypeScript, Node.js, PostgreSQL, Python, ML, ML Ops, SOC 2, FBI CJIS
2w
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Software Developer, Senior (8061)
Niskayuna or West Mifflin or West Milton or Idaho Falls or Goose Creek
$96k-$150k/yr OnsiteFull Time
Naval Nuclear Laboratory
Naval Nuclear Laboratory: Operates and maintains U.S. naval nuclear propulsion systems.
4+ YOEBachelor's+6yrs or Master's+4yrs in a related field; proficiency with Python/C#/Java/TypeScript; experience integrating AI/ML, cloud, containers, and CI/CD; U.S. citizenship and ability to pass federal background and drug screening.
Python, C#, Java, TypeScript, LLMs, Azure, AWS, OCI, containers, CI/CD
2w
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Senior AI Engineer
Philadelphia or Pennsylvania or New Jersey or Delaware or Maryland or Texas or Georgia or Iowa or Illinois or Indiana or Kansas or North Carolina or South Carolina or Tennessee or Vermont or West Virginia
$146k-$182k/yr HybridFull Time
NBME
NBME: Develops and manages medical licensing and healthcare professional assessments.
5+ YOEBachelor's or Master's in CS/Engineering/Data Science, 5+ years AI/ML engineering experience, proficiency with Python, PyTorch, TensorFlow, Hugging Face Transformers, cloud (AWS/GCP/Azure), Docker, Kubernetes, and familiarity with vector DBs and embeddings.
Python, PyTorch, TensorFlow, Hugging Face Transformers, AWS, GCP, Azure, Docker, Kubernetes
2w
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Senior CNO Developer (Onsite)
Annapolis Junction or Palm Bay or Dulles or Maryland or Florida or South Carolina or Texas
$99k-$206k/yr RemoteFull Time
Nightwing
Nightwing: Provides advanced cyber and intelligence solutions for national security.
7+ YOE5+ MgmtBachelor's +9 yrs or Master’s +7 yrs; 8+ yrs programming in Assembly, C, C++, Java, Perl, and/or Python; experience with Windows/UNIX build environments; CNO tooling experience; 5+ yrs managing teams; TS/SCI preferred.
Assembly, C, C++, Java, Perl, Python, Visual Studio, .NET, make, Bash, PowerShell, IDA Pro, Ghidra, OllyDbg, Git, Windows, UNIX
1mo
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Manufacturing IT Platform Senior Engineer
West Union or Holland or MeadowBrook
OnsiteFull Time
Clarios
Clarios: Manufacturer and distributor of advanced low-voltage automotive batteries.
8+ YOE8+ years software development in manufacturing, 2–3 years using AI-assisted development tools, strong coding in Python/Java/Node.js/.NET, REST APIs, Docker, Kubernetes, MoM/MES knowledge, and experience with edge deployments and plant support.
Claude.ai, ChatGPT, GitHub Copilot, Copilot studio, Python, Java, Node.js, .NET, Docker, Kubernetes, MQTT, MoM, MES, SCADA, Historian, CI/CD
1mo
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Senior Software Engineer
San Francisco or Knoxville or New York City or Arizona or California or Colorado or Connecticut or Florida or Georgia or Illinois or Louisiana or Massachusetts or Minnesota or North Carolina or New Jersey or Nevada or New York or Ohio or Pennsylvania or South Carolina or Tennessee or Texas or Washington or Virginia or District of Columbia
$150k-$224k/yr RemoteFull Time
Verana Health
Verana Health: Curates real-world clinical data to accelerate medical research and insights.
5+ YOE5+ years backend development with Java and Spring Boot, experience with AWS, Docker, Kubernetes, CI/CD, TDD/JUnit, REST/microservices, observability (Datadog, CloudWatch, OpenTelemetry), mentoring skills, and experience with RDBMS, Elasticsearch and NoSQL.
Java, Spring Boot, AWS, GHA, Jenkins, Docker, Kubernetes, JUnit, TDD, REST, OAuth 2.0, OWASP, Elasticsearch, NoSQL, Datadog, CloudWatch, OpenTelemetry, React, WebSockets, Python, Kafka, SQS, CI/CD
1mo
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Senior Data Engineer-JT0224
Alabama or Arkansas or Delaware or Florida or Georgia or Iowa or Illinois or Indiana or Kansas or Kentucky or Louisiana or Massachusetts or Maine or Maryland or Michigan or Minnesota or Missouri or Mississippi or Montana or North Carolina or Nebraska or New Hampshire or Ohio or Oklahoma or Pennsylvania or Rhode Island or South Carolina or Tennessee or Texas or Virginia or Wisconsin or West Virginia
RemoteFull Time
Revecore
Revecore: Identifies and recovers underpaid medical claims for hospital systems.
Expertise in Azure cloud services, data lakehouse architecture, ELT pipelines, Python, SQL, and C#. Experience with Snowflake, dbt, Airflow, Terraform/CloudFormation, and CI/CD. Bachelor's or Master's in CS or equivalent experience.
Azure Synapse, Azure Data Lake Storage Gen2, Azure DevOps Pipelines, Power BI, Snowflake, dbt, Airflow, Python, SQL, C#, .NET Framework, .NET Core, Terraform, CloudFormation
14h
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Senior Software Engineer, Golang
Charlotte or Fort Mill or Denver or Minneapolis
$119k-$150k/yr HybridFull Time
RVO Health
RVO Health: Provides digital health information and consumer wellness solutions.
5+ YOEBachelor's or equivalent,5+ years software development experience,proficiency in Go and multiple languages,experience with testing,AWS and IaC preferred,strong problem-solving and communication skills.
Golang, Go, PHP, JavaScript, Python, TypeScript, Java, C#, C++, Node.js, GraphQL, REST APIs, NoSQL, AWS, IaC
4w
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Senior Platform Software Engineer
Needham or California or Connecticut or Florida or Georgia or Illinois or Massachusetts or Maryland or Maine or Michigan or New Hampshire or New Jersey or New York or North Carolina or Pennsylvania or Rhode Island or South Carolina or Tennessee or Texas or Utah or Washington or Virginia
$150k-$172k/yr RemoteFull Time
Advisor360°
Advisor360°: Provides an integrated SaaS platform for wealth management firms.
8+ YOE8+ years platform/software engineering experience; hands-on Jenkins (Groovy), Python, Ansible, Kubernetes, .NET (C#); CI/CD, RESTful APIs, observability (Dynatrace, ELK Stack); on-call participation and mentoring experience.
Jenkins, Groovy, Python, Kubernetes, .NET (C#), Ansible, RESTful APIs, Dynatrace, ELK Stack, Angular
2mo
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Sr Software Developer/Engineer
North Charleston, South Carolina, United States
OnsiteFull Time
Scientific Research Corporation
Scientific Research Corporation: Advanced engineering and technology solutions for government and industry.
5+ YOEFive+ years in large software projects; Java; Linux development; Ansible; CI/CD; VMware/KVM; containers; Oracle DB; strong communication; experience with C/C++/Python; remote team management.
Java, Ansible, Jenkins, Git, Artifactory, JIRA, VMware, KVM, Containers, Oracle, C, C++, Python
1mo
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Senior Analytics Engineer
Boston or Arizona or California or Colorado or Connecticut or Florida or Idaho or Illinois or Kentucky or Maine or Maryland or Massachusetts or Michigan or Missouri or Nevada or New Hampshire or New Jersey or New York or North Carolina or South Carolina or Ohio or Oklahoma or Pennsylvania or Rhode Island or Tennessee or Texas or Utah or Virginia
$110k-$135k/yr RemoteFull Time
829 Studios
829 Studios: Integrated digital marketing agency providing data-driven strategy and web development.
5+ YOEBachelor's in a quantitative field, 5+ years in BI development (consulting preferred), 3+ years Python, 4+ years SQL, dbt experience, BI dashboarding (Tableau/Sigma), client-facing consulting and presentation skills.
Snowflake, BigQuery, dbt, Python, SQL, Tableau, Sigma, AWS, Azure, GCP