60 senior python developer jobs at 54 companies in Independence, KS
1w
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Senior Python Developer (Technology & AI Labs)
United States
RemoteFull Time
5+ YOE5+ years Python full-stack experience with FastAPI/Django/Flask, React, PostgreSQL and NoSQL (MongoDB), cloud (AWS or Microsoft Azure), CI/CD, and AI-assisted development experience.
FastAPI, Django, Flask, React, PostgreSQL, MongoDB, SQLAlchemy, Django ORM, AWS, Microsoft Azure, GitHub Actions, GitLab CI, Azure DevOps, ECS, EKS, App Service, Lambda, Azure Functions, Secrets Manager, Key Vault, S3, Blob Storage, SQS, SNS, Service Bus, CloudWatch, Application Insights, pytest, uv, ruff, mypy, Claude Code, Codex, GitHub Copilot, Cursor, JetBrains AI, TypeScript, .NET, C#, Node.js, Go, Alembic, pgvector, Pinecone, Weaviate, pandas, NumPy, LangChain, LlamaIndex
2mo
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Senior Software Engineer - Front End Developer
Home, Virginia, United States
$91k-$178k/yr RemoteFull Time
5+ YOESenior front-end engineer with 5+ years exp, BS in Software Engineering/CS, US citizenship, ability to obtain Secret clearance.
HTML, CSS, JavaScript, React, Vue, Angular, Next.js, Vite, Webpack, Rollup, TailwindCSS, CSS-in-JS, styled-components, RBAC, RESTful APIs, WebSockets, Pub/Sub, Python, FastAPI, SQL, Redis
3w
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Senior Software Engineer
United States
$110k-$125k/yr RemoteFull Time
7+ YOE7+ years web application development experience; expert Python; JavaScript/TypeScript and React; experience with MongoDB or SQL, Git, Docker; AWS/Kubernetes a plus; strong communication and problem-solving.
Python, JavaScript, TypeScript, React, MongoDB, SQL, Git, Docker, AWS, Kubernetes
2w
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Senior Software Engineer II
United States
$155k-$260k/yr RemoteFull Time
8+ YOE8+ years software engineering, Bachelor's in CS/Engineering or equivalent, strong fundamentals in Golang or Python, experience with LLMs/AI agents, distributed backend and edge systems, mentoring and strong communication.
Golang, Python, Codex, Claude Code, Cursor, LLMs, Tofu
2mo
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Senior Software Engineer - DevX
United States
$191k-$267k/yr RemoteFull Time
5+ YOE5+ years professional software development with backend/infrastructure/platform focus; strong Go experience; distributed systems, API design, Kubernetes, and mentoring skills required.
Go, GraphQL, REST, HTTP, gRPC, Kubernetes, GitHub Enterprise Server, Python
2w
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Senior AI/ML Engineer
United States
OnsiteFull Time
8+ YOE8+ years software/AI engineering experience,2+ years building/deploying GenAI/LLM production applications,proficient Python,experience with RAG,vector DBs,agentic architectures.
LangChain, LangGraph, HyDE, Pinecone, Weaviate, PGVector, AWS Bedrock, Bedrock Agents, Ragas, LangSmith, Phoenix, Model Context Protocol (MCP), FastAPI, Docker, OpenTelemetry, Claude, GPT-4o, Llama 3, Mistral, Fireworks AI, Groq, Python
2w
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Senior AI solutions Engineer
United States
OnsiteFull Time
5+ YOE5+ years in technical data roles with 2+ years deploying LLMs, MCP experience, strong SQL (PostgreSQL/Presto), Python (Pandas/NumPy/FastAPI), REST/GraphQL/OAuth, and consultative communication skills.
Model Context Protocol (MCP), Salesforce, Salesintel, HubSpot, Jira, Confluence, PostgreSQL, Presto, REST, GraphQL, OAuth, webhooks, Python, Pandas, NumPy, FastAPI, Claude Cowork, Claude Code, Claude Skills, LangChain, LlamaIndex, Apache Superset, Scikit-learn, RStudio, PyCharm, VS Code, AWS QuickSight, Microsoft Power BI, Git, AWS Lambda, S3, Athena, Apache Airflow
1w
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Senior Software Engineer, Data
United States
RemoteFull Time
5+ YOE5+ years backend engineering experience building APIs, data schemas, and LLM-backed features; strong C# .NET, Python, SQL, Snowflake, PostgreSQL, and AWS skills; CI/CD and data modeling experience.
C# .NET, Python, SQL, AWS, Snowflake, PostgreSQL, LLM, Git, GitHub, CI/CD, MCP
4w
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Senior Software Engineer Applied AI
Charleston or United States
RemoteFull Time
7+ YOE7+ years building and operating production backend systems, strong Python skills, distributed cloud experience, hands-on LLM/generative AI experience, and regulated-environment discipline.
Python, AWS, LLMs
2w
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Senior Security Engineer
United States
$220k-$260k/yr RemoteFull Time
Experienced security generalist with strong application-security skills, Python code auditing, CI/CD/cloud security, supply-chain and incident-response experience; bachelor's or equivalent.
Python, Semgrep, Bandit, CodeQL, Burp Suite, GitHub Actions, Docker, PyPI, SBOMs, Sigstore, Cosign, Snyk, Grype, Trivy
2w
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Senior Site Reliability Engineer
United States
$160k-$208k/yr RemoteFull Time
5+ YOE5+ years programming experience; proficiency in Python, Go, or shell scripting; Kubernetes, containerization, cloud platforms, Linux, networking, monitoring and SRE concepts.
Python, Go, Shell Scripting, Docker, containerd, Kubernetes, Helm, gRPC, Prometheus, GCP, Azure, AWS, Linux
3w
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Senior Engineer, Healthcare Data
United States
$160k-$190k/yr RemoteFull Time
6+ YOE6+ years in data engineering or health IT, end-to-end pipeline ownership, AI-native experience with coding agents, PHI-safe practices, strong Python and SQL skills, FHIR and interoperability knowledge.
Claude Code, Apache Spark, PySpark, Databricks, Delta Lake, Python, SQL, Git, CI/CD, HL7 FHIR R4, US Core, USCDI, HL7 v2.x, C-CDA, SNOMED CT, LOINC, RxNorm, ICD-10, CPT, CVX
3w
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Principal Software Engineer
United States
$143k-$275k/yr OnsiteFull Time
6+ YOEBachelor's degree and 6+ years engineering experience (or equivalent); coding in C,C++,C#,Java,JavaScript,or Python; Microsoft cloud security screening required.
C, C++, C#, Java, JavaScript, Python, Azure
2w
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Senior Business Systems Engineer (Salesforce & Billing Platform)
United States
$145k-$165k/yr OnsiteFull Time
5+ YOE5+ years Salesforce development experience with Apex, Flow, and LWC; experience with AI-driven tooling, Quote-to-Cash/billing platforms, and CI/CD; bachelor's degree or equivalent; Python experience and Salesforce certifications preferred.
Einstein, Agentforce, Apex, Flow, Lightning Web Components (LWC), Copilot, Orb, Metronome, Chargebee, Python, Salesforce, LLM
6d
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Sr Data Engineer
United States
$150k-$200k/yr RemoteFull Time
5+ YOE5+ years data engineering experience, strong SQL, Python/PySpark/Scala, cloud data platforms (preferably AWS), data warehousing (Snowflake/Redshift/BigQuery/Synapse/Databricks), Apache Spark, ETL/ELT pipelines, and data governance knowledge.
SQL, Python, PySpark, Scala, AWS, Snowflake, Redshift, BigQuery, Synapse, Databricks, Apache Spark, Delta Lake, Airflow, dbt
2mo
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Trading Systems Senior Engineer
Farmington, Connecticut, United States
HybridFull Time
5+ YOE5+ years in trading systems, SQL, APIs; Charles River experience; Azure migration; software engineering in regulated environment.
Charles River, Azure, APIs, SaaS, Python, C#, SQL
1w
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Forward Deployed Engineer
United States
$169k-$214k/yr RemoteFull Time
5+ YOE5+ years software engineering experience, hands-on with LLM APIs/agentic systems, Python proficiency, enterprise integration experience, strong communication and retail systems knowledge.
LLM APIs, Python, RAG
1mo
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Senior Software Engineer
United States
$124k-$329k/yr RemoteFull Time
6+ YOE6+ years software engineering experience (or equivalent), experience building agent-based LLM experiences, front-end and back-end proficiency, cloud and CI/CD familiarity, strong communication and technical leadership.
Copilot, React, CSS, HTML, JavaScript, TypeScript, Go, Ruby, Rust, Python, Bash, Cloud Native Compute Foundation (CNCF)
4d
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Senior Systems Engineer
United States
$165k/yr RemoteFull Time
5+ YOE5+ years system design, build, and integration experience; Linux packaging, configuration management, CI/CD, container orchestration, networking, scripting, and cybersecurity experience required.
Linux, systemd, Artifactory, cargo, go build, npm, Maven, Gradle, GitHub Actions, Docker, Kubernetes, NGINX, Python, Bash, Makefile, Rust, AWS, Microsoft Azure
2w
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Gen AI Engineer
United States
RemoteFull Time
7+ YOE7+ years software/AI engineering experience; strong Python; experience with AWS Bedrock, Generative AI/LLM integration, DevOps/CI/CD, RAG and agentic AI; familiarity with OpenAI API and JSON RESTful design.
AWS, AWS Bedrock, Python, OpenAI API, JSON, Pinecone, Weaviate, pgvector, LangChain, CrewAI, Semantic Kernel, RAGAS, TruLens, CI/CD
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