2,116 senior python developer jobs at 574 companies in Tewksbury, MA
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Senior Python Developer
Montreal or India or Boston or Brossard
HybridFull Time
5+ YOESenior Python engineering experience required, with Python, FastAPI, Pydantic, AWS, cloud-native systems, databases, APIs, automated testing, CI/CD, and Generative AI or agentic framework experience.
Python, FastAPI, Pydantic, AWS, PostgreSQL, NoSQL, CI/CD, Generative AI, API, microservices
3mo
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Senior Python Software Engineer
Boston, Massachusetts, United States
$119k-$180k/yr RemoteFull Time
5+ YOEBachelor's in computer science/engineering or related field, 5+ years of experience; Python 3; SQL/NoSQL; unit tests; scalable backend services; Unix/Linux (AWS); financial industry knowledge.
Python, SQL, NoSQL, MongoDB, Unix, AWS, Git, Jenkins, Grunt
3mo
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Principal Python Engineer (Modeling & Simulation)
San Francisco or Boston or United States
HybridFull Time
7+ YOE7+ years Python software development, experience with scalable APIs, Docker, cloud distributed systems, stakeholder-driven design, SDLC best practices; eligible for U.S. Top Secret clearance.
Python, Docker, REST, GraphQL, gRPC, AWS, GCP, Azure
3mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
3mo
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Senior Software Engineer
Washington or Boston
$129k-$194k/yr OnsiteFull Time
Strong Python, distributed systems, cloud platforms, AI/ML, LLMs, autonomous agents, senior IC.
Python, AWS, GCP, Azure, Jira, Git, LLMs, AI agent tooling
3mo
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Sr. Software Engineer - Signals & Algorithm Interfaces (Python/C++)
Newton or Mounds View
$125k-$187k/yr OnsiteFull Time
4+ YOESenior software engineer with strong Python/C++ skills, real-time data pipelines, and production software delivery experience.
Python, C++, Linux, Docker, CI/CD, Distributed systems, Networking, Debugging
3mo
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Senior Software Engineer, Lab Software
Cambridge, Massachusetts, United States
$144k-$210k/yr OnsiteFull Time
5+ YOESenior backend-focused software engineer with 5-8+ years of experience building large-scale systems; full-stack development; Python, FastAPI, React, TS, SQL/NoSQL; cloud, AWS, Kubernetes; collaboration with scientists.
React, TypeScript, Tailwind, FastAPI, SQL, NoSQL, Python, Pydantic, AWS, Kubernetes, Terraform, CloudFormation, GitHub Actions, Airflow, Prefect, Temporal, Dagster
3mo
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Principal Software Engineer - Python
Boston, Massachusetts, United States
$150k-$300k/yr RemoteFull Time
12+ YOE12+ years of production Python development; enterprise SaaS; open-source tools; FastAPI; Pydantic; strong English communication; unrestricted right to work in the United States.
Python, Git, FastAPI, Pydantic
4mo
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Senior Software Engineer
Boston or Needham
$90k-$180k/yr HybridFull Time
5+ YOE5+ years in software design/development; full stack experience; Java/Python/TypeScript; AWS/Azure; CI/CD; JIRA/Git; AI tools; strong communication.
Java, Python, TypeScript, AWS, Azure, Jenkins, GitHub Actions, JIRA, Git, VS Code, IntelliJ, Eclipse, Oracle, MySQL, Claude Code, GitHub Copilot
4mo
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Senior Software Engineer
Boston or Needham
$90k-$180k/yr HybridFull Time
5+ YOE5+ years of software development experience; full stack capabilities; AI-driven engineering exposure; proficient with Java, Python, TypeScript; SDLC tools; cloud platforms; strong communication.
JIRA, Git, Jenkins, GitHub Actions, VS Code, IntelliJ, Eclipse, Claude Code, GitHub Copilot, AWS, Azure, Java, Python, TypeScript, Oracle, MySQL
3mo
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Senior Software Engineer
Boston, Massachusetts, United States
HybridFull Time
5+ YOEBS in CS/Math/Stats; MS/PhD preferred; 5+ years software eng; senior/lead on AWS cloud; strong Python; ML frameworks; production ML systems; AWS AI services; data pipelines; SQL; CI/CD; REST/microservices; Agile.
Python, C#/.NET, AWS, SageMaker, S3, Glue, Athena, Lambda, EC2, CloudWatch, Docker, Kubernetes, Apache Spark, Airflow, dbt, SQL, PostgreSQL, MSSQL, REST API
2mo
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Senior SW Engineer
Westford, Massachusetts, United States
$125k-$179k/yr OnsiteFull Time
Bachelor’s degree; Linux development; strong C++ and Python; network protocols (BGP/IGP); SRv6 and EVPN/VxLAN; virtualization (Docker/Containers); distributed systems; gNOI; good OS knowledge.
Linux, C++, Python, Docker / Containers, gNOI, SRv6, EVPN / VXLAN, Networking protocols, Operating systems concepts
2w
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Senior Agentic AI Engineer (Python)_Boston
Boston, Massachusetts, United States
$48k-$168k/yr OnsiteFull Time, Contract
5+ YOERequires 5–10 years of software engineering experience, strong Python expertise, 3+ years of AI/ML experience, and production experience with generative AI, LLMs, RAG, agentic frameworks, APIs, and observability.
Python, LangChain, LangGraph, OpenAI SDK, Azure OpenAI, AWS Bedrock, Google Vertex AI, pgvector, OpenSearch, Pinecone, Weaviate, SharePoint, Confluence, Salesforce, Docker, Kubernetes
3w
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Senior Java Full Stack Developer – Python & Angular (Hybrid)
Westborough or Boston
$65k-$112k/yr HybridFull Time
7+ YOE7+ years developing scalable enterprise applications with Java, Python, and Angular; experience with Oracle/PL/SQL, test automation, DevOps practices, Git, and Agile tools; US work authorization required.
Java, Python, Angular, Oracle, PL/SQL, Git, JIRA, Zephyr Scale, Confluence, AI-assisted development tools
3mo
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Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes)
San Francisco or Cambridge or McLean or New York or San Jose
$230k-$286k/yr HybridFull Time
6+ YOE1+ MgmtBachelor’s degree; 6+ years software engineering; 1+ year cloud experience; 9+ years in Python/Golang/Node.js; 4+ years cloud services; 4+ years open source frameworks; 2+ years Kubernetes; 1+ year people management; 2+ years ML platform experience
Golang, Python, JavaScript, Java, TypeScript, SQL, HTML, CSS, Docker, Kubernetes, AWS, GCP, Azure, NoSQL, RDBMS
3w
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Senior Software Engineer - Backend Python
Nashua, New Hampshire, United States
$97k-$165k/yr OnsiteFull Time
6+ YOEBachelor's in CS or related, 6+ years backend Python experience, mastery of Python 3.x and AsyncIO, gRPC/Protobuf, Docker/Kubernetes, PostgreSQL, and ability to obtain U.S. Secret clearance.
Python, AsyncIO, gRPC, Protocol Buffers (Protobuf), FastAPI, Flask, Django, PostgreSQL, SQLAlchemy, Docker, Kubernetes, Kafka, RabbitMQ, Redis, C#, OAuth2, JWT
3mo
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Senior Software Engineer, Product Integrations
Waltham, Massachusetts, United States
$130k-$200k/yr OnsiteFull Time
5+ YOE5+ years software development; Linux; RESTful APIs; Python or Go; US work authorization; bachelor’s degree preferred; strong communication.
Python, Go, Linux, PostgreSQL, Jenkins, Ansible, REST API, AWS
3mo
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Senior Platform Engineer
Atlanta or Boston or Chicago or Dallas or New York
HybridFull Time
6+ YOE6+ years backend platform engineering; Kubernetes, Python, Postgres, Kafka, Redis; security and AI tooling.
Python, FastAPI, Pydantic, SQLAlchemy, Alembic, PostgreSQL, Redis, Kafka, Docker, Kubernetes, OpenTelemetry, Prometheus, Helm, Vault, Azure Key Vault, Azure Monitor
2mo
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Principal Software Engineer (Python)
Hinjewadi or Pune or Burlington or Europe or Asia or North America
HybridFull Time
8+ YOEBachelor's in Engineering/CS, 8+ years experience (5+ with Python), strong OO design, experience building AI agents, CI/CD, cloud, containers, databases, excellent communication and problem-solving skills.
Python, Java, git, Bamboo, Jenkins, JSON, XML, HTTP, RESTful, PostgreSQL, MySQL, Kubernetes, K8s, Docker, Envoy, Terraform, Azure, AWS, CICD
3mo
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Senior Software Engineer
Boston, Massachusetts, United States
OnsiteFull Time
Senior software engineer with experience in big data streaming, multi-tier web apps, AWS hosting/DevOps, and strong design skills; proficient in server-side languages and databases; Agile/Scrum experience; collaborative mindset.
AWS, AWS Kinesis, Apache Kafka, ASP.NET Core, Angular, Docker, Kubernetes, SQL Server, PostgreSQL, MongoDB, HTML, CSS, JavaScript, TypeScript, Python, C#
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