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8,800 senior python engineer jobs at 1,781 companies in California

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
1mo
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Python Developer - 6249754
New York City or Cleveland or California or Colorado or District of Columbia or Illinois or Maine or Maryland or Massachusetts or Minnesota or New Jersey or New York or Virginia or Washington
$22-$72/hr HybridFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
5+ YOEMinimum 5 years experience, advanced Python proficiency, Associates degree required (Bachelor's preferred). Preferred experience with Oracle NoSQL, MongoDB, React.js, application remediation and engineering support.
Python, Oracle NoSQL Database, MongoDB, React.js
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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2mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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3mo
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Senior Software Engineer - Python
San Jose or Austin
$144k-$213k/yr HybridFull Time
PayPal
PayPalNASDAQ: PYPL: Digital platform for sending money and processing online payments.
3+ YOE3+ years Python backend experience; Bachelor's degree or equivalent; Django/Flask; SOA; REST/Web services; Git; cloud familiarity; SQL/NoSQL; CI/CD; distributed systems.
Python, Django, Flask, Git, AWS, GCP, Azure, Terraform, SQL, NoSQL, Redis, SQS, Kafka, CI/CD, Observability
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2mo
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Principal Python Engineer (Modeling & Simulation)
San Francisco or Boston or United States
HybridFull Time
Code Metal
Code Metal: Verifiable AI-powered code translation for mission-critical industries.
7+ YOE7+ years Python software development, experience with scalable APIs, Docker, cloud distributed systems, stakeholder-driven design, SDLC best practices; eligible for U.S. Top Secret clearance.
Python, Docker, REST, GraphQL, gRPC, AWS, GCP, Azure
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2mo
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Senior Software Development Engineer in Test (Python Automation)
San Jose, California, United States
$148k-$296k/yr HybridFull Time
Nutanix
NutanixNASDAQ: NTNX: Sells cloud software and hyperconverged infrastructure for enterprises.
8+ YOE8+ years experience in test engineering; strong Python automation, Kubernetes/Docker, test automation, cloud/infrastructure testing.
Python, Kubernetes, Docker, Postman, JMeter
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1mo
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Senior Production Engineer
San Francisco or Sunnyvale
$209k-$253k/yr OnsiteFull Time
Crusoe
Crusoe: Provides energy-efficient cloud infrastructure powered by stranded and renewable energy.
Senior production engineer with distributed systems experience, hands-on with large language models, SRE mindset, and strong programming skills (Python, Go, Java, or C++), Kubernetes knowledge, and collaborative skills.
Python, Go, Java, C++, Kubernetes
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Python Test Automation Engineer
Los Angeles, California, United States
$140k-$150k/yr OnsiteFull Time
EPAM Systems
EPAM SystemsNYSE: EPAM: Provides global digital platform engineering and software development services.
Bachelor's in a relevant engineering or CS field; proven experience building Python-based test automation frameworks, robotic automation fixtures integration, Git/GitHub/GitLab, UNIX, and Jenkins; sensor validation experience; Master's degree preferred.
Python, UNIX, Jenkins, Git, GitHub, GitLab, CI/CD, Anthropic Claude, Claude Code, LinkedIn Learning
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2w
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Senior Engineer - Python
Cupertino, California, United States
$100k-$150k/yr OnsiteFull Time
Tata Consultancy Services
Tata Consultancy ServicesNational Stock Exchange of India: TCS: Global provider of IT services, consulting, and business solutions.
7+ YOEBachelor's degree or equivalent, 7+ years experience, strong Python and FastAPI skills, Docker/Kubernetes, SQS, API and microservice design, observability with OpenTelemetry/Elastic Stack.
Python, FastAPI, Docker, Kubernetes, SQS, OpenTelemetry, Elastic Stack, OpenAPI, Swagger
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2mo
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ASIC Senior Verification Engineer
Roseville, California, United States
$154k-$311k/yr OnsiteFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Providing global edge-to-cloud infrastructure and IT solutions for businesses.
10+ YOESenior verification engineer with 10+ years in VLSI design/verification; strong Verilog/SystemVerilog, UVM; scripting (Python, Perl, TCL); C/C++; leadership.
Verilog, SystemVerilog, UVM, Python, PERL, TCL, C, C++, Specman
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1mo
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Senior Staff Engineer, Developer Infrastructure & Experience
Palo Alto, California, United States
OnsiteFull Time
Hippocratic AI
Hippocratic AI: Develops safety-focused generative AI for autonomous clinical healthcare conversations.
12+ YOESenior staff engineer with 12+ years of software engineering experience, backend fluency in Python/Go/Java, CI/CD ownership, and production deployments with feature flags and progressive rollouts; strong design and safety-focused engineering.
Python, Go, Java, CI/CD, Feature flags, Canary deployments, Blue/Green, Observability, AI-assisted development tools
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2mo
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Senior Physical Design Engineer
Saratoga, California, United States
$120k-$220k/yr OnsiteFull Time
E-Space
E-Space: Builds sustainable LEO satellite networks for global IoT connectivity
8+ YOESenior Physical Design Engineer with 8+ years in ASIC/SoC physical design; Cadence Innovus expertise; floorplanning, CTS, routing; timing closure; scripting (Python/Tcl).
Cadence Innovus, Synopsys ICC2, Mentor Calibre, Tcl, Python, Verilog, SystemVerilog, UVM, VHDL
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2mo
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Senior Hardware Engineer
Santa Clara, California, United States
$180k-$326k/yr OnsiteFull Time
Pure Storage
Pure StorageNYSE: PSTG: Provides all-flash enterprise data storage and management solutions.
Senior hardware engineer with expert hardware design, x86 architecture, high-speed SI, validation automation, and scripting across PCIe and Ethernet.
Python, Bash, ECAD tools, Oscilloscopes, Bus analyzers
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2mo
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Senior Digital Engineer
Sydney or Sydney or Irvine or Boston or Bangalore or Cambridge or Hangzhou or Taipei or Tokyo or Sydney
OnsiteFull Time
Morse Micro
Morse Micro: Develops low-power Wi-Fi HaLow semiconductor chips for IoT.
5+ YOE5+ years as Senior Digital Engineer; strong Verilog/SystemVerilog; RTL design; low-power techniques; collaborate with firmware/PHY teams.
Verilog/SystemVerilog, C, Python, Tcl, Shell, Makefiles, UPF/CPF, Scripting and automation
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2mo
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Senior Performance Engineer, Data Protection & Security Platform Engineering
Santa Clara, California, United States
$179k-$199k/yr OnsiteFull Time
Cohesity
Cohesity: AI-powered data security and management software provider.
5+ YOESenior performance engineer with 5+ years in distributed systems; strong Golang/Python; experience with storage, cloud, and security platforms.
Golang, Python, Automation, Performance tooling
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2mo
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Senior systems engineer
Milpitas, California, United States
$128k-$192k/yr OnsiteFull Time
Onto Innovation
Onto InnovationNYSE: ONTO: Provides metrology and inspection solutions for semiconductor manufacturers.
3+ YOEMaster’s or Ph.D. in Physics, Electrical/Mechanical Engineering, or Applied Optics; 3+ years (3–15+ for senior roles) in complex system development; strong optics, control engineering, and software/hardware integration; Python, MATLAB, JMP, LabVIEW.
Python, MATLAB, JMP, LabVIEW
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2mo
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Senior GNC Engineer
Moorpark, California, United States
$150k-$164k/yr OnsiteFull Time
Quantum-Systems
Quantum-Systems: Develops and manufactures autonomous AI-powered unmanned aerial systems.
5+ YOESenior GNC Engineer with 5+ years in drone flight dynamics, control, state estimation; lead GNC algorithms; U.S. citizen; potential security clearance; Moorpark office commute.
MATLAB, Simulink, Python, C/C++, PX4, ArduPilot, ROS/ROS2, Gazebo, PX4 SITL, MATLAB/Simulink, SITL
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1mo
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Senior Electromechanical Engineer
El Segundo, California, United States
$151k-$227k/yr OnsiteFull Time
The Aerospace Corporation
The Aerospace Corporation: Provides technical expertise and research for national space programs.
10+ YOESenior electromechanical engineer with 10+ years in electromechanical control systems, verification, and space hardware; bachelor's in a STEM field; willing to obtain security clearance; able to travel up to 25%.
MATLAB/Simulink, LabVIEW, SolidWorks, C/C++, Python
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1mo
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Senior Reliability Engineer
San Francisco, California, United States
$150k-$180k/yr OnsiteFull Time
Eight Sleep
Eight Sleep: Develops smart mattresses and temperature-regulated sleep technology.
5+ YOE5+ years reliability engineering in electromechanical systems; experience with DOE, FMEA, Weibull, SPC; Python/MATLAB; hardware test equipment; strong collaboration.
Python, MATLAB, LabVIEW, JMP
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3mo
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Senior Test Engineer
Colorado Springs or San Jose
$108k-$155k/yr OnsiteFull Time
Sanmina
SanminaNASDAQ: SANM: Designs and manufactures complex electronics and mechanical systems.
8+ YOEBS in engineering or computer science; 8+ years in test engineering; strong OS knowledge (Linux/Windows/Unix); scripting (Python, Bash); hardware/software interop; BMC/BIOS/SES firmware experience preferred; GPU testing a plus.
Python, Linux, Bash, Git, Jira, Bugzilla, Windows, Unix, BMC, BIOS, SES, GPU testing
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