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2,294 senior python engineer jobs at 787 companies in Napa, CA

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
2mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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2mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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2mo
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Principal Python Engineer (Modeling & Simulation)
San Francisco or Boston or United States
HybridFull Time
Code Metal
Code Metal: Verifiable AI-powered code translation for mission-critical industries.
7+ YOE7+ years Python software development, experience with scalable APIs, Docker, cloud distributed systems, stakeholder-driven design, SDLC best practices; eligible for U.S. Top Secret clearance.
Python, Docker, REST, GraphQL, gRPC, AWS, GCP, Azure
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1mo
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Senior Production Engineer
San Francisco or Sunnyvale
$209k-$253k/yr OnsiteFull Time
Crusoe
Crusoe: Provides energy-efficient cloud infrastructure powered by stranded and renewable energy.
Senior production engineer with distributed systems experience, hands-on with large language models, SRE mindset, and strong programming skills (Python, Go, Java, or C++), Kubernetes knowledge, and collaborative skills.
Python, Go, Java, C++, Kubernetes
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1mo
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Senior Reliability Engineer
San Francisco, California, United States
$150k-$180k/yr OnsiteFull Time
Eight Sleep
Eight Sleep: Develops smart mattresses and temperature-regulated sleep technology.
5+ YOE5+ years reliability engineering in electromechanical systems; experience with DOE, FMEA, Weibull, SPC; Python/MATLAB; hardware test equipment; strong collaboration.
Python, MATLAB, LabVIEW, JMP
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2mo
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Senior Mechanical Engineer
San Francisco, California, United States
$165k-$227k/yr RemoteFull Time
Juul Labs
Juul Labs: Produces electronic vaporizers and nicotine pods for adult smokers.
8+ YOE8+ years mechanical engineering; experience with medical devices or regulated products; overseas supplier collaboration; Python proficiency; 3D MCAD (SolidWorks) and EC/mechanical integration.
Python, SolidWorks, 3D CAD, FEA, CFD, DFMEA, Design of Experiments
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3mo
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Senior Firmware Engineer- Medical
Brisbane, California, United States
$150k-$180k/yr HybridFull Time
Avive
Avive: Sells connected automated external defibrillators and emergency medical software.
4+ YOESenior firmware engineer for embedded medical devices; leadership role in design, coding, debugging, and production releases; strong C/C++ and embedded systems experience.
C, C++, Embedded Systems, ARM, PIC32, RTOS, Linux, Git, Jira, Python, Oscilloscopes, Multimeters, Schematic reading
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2mo
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Senior ML/AI Engineer
San Francisco or New York
OnsiteFull Time
Beast Industries
Beast Industries: Produces digital media and consumer goods for MrBeast brands.
5+ YOESenior ML/AI engineer with production experience, AI-native mindset, strong eval framework, and ability to ship features at consumer scale.
Python, Machine Learning, Model Serving, Inference Infrastructure, Retrieval-Augmented-Generation, Agent Frameworks, Evaluation Systems, Prompt Engineering, Coding Agents
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1mo
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
Tyba
Tyba: AI software for modeling and operating renewable energy projects.
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
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2mo
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Senior Research Engineer, Voice + Speech
San Francisco, California, United States
$200k-$400k/yr OnsiteFull Time
Decagon: Conversational AI platform for automated customer support.
5+ YOE5+ years AI/ML engineering or research; production deployment of LLMs; Python and ML tooling; roadmap, milestones, cross-functional leadership.
Python, Machine Learning tooling, Data pipelines, Model training, Evaluation
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2mo
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Senior Applied AI Engineer
San Francisco, California, United States
OnsiteFull Time
Alterion
Alterion: Building a control plane for enterprise AI agents.
5+ YOE5+ years in software/ML engineering; strong Python; production services; LLMs experience; model evaluation and monitoring; PyTorch or similar.
Python, PyTorch, LLMs, Machine Learning Pipelines, APIs
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2mo
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Senior Software Engineer
San Francisco, California, United States
$180k-$215k/yr OnsiteFull Time
HeartFlow
HeartFlowNASDAQ: HTFL: Provides AI-driven non-invasive cardiac diagnostic software and analysis.
3+ YOESenior Software Engineer with strong Python, AWS, Django/JS, TypeScript, CI/CD, and experience building cloud-native APIs and web applications in regulated environments.
Python, AWS, Django, JavaScript, TypeScript, Nginx, Pytest, GitHub, GitHub Actions, Kubernetes, CDK, Step Functions, Lambdas, API Gateway, Fargate, ECS, Aurora
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3mo
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Senior Controls Engineer
San Francisco, California, United States
$100k-$200k/yr OnsiteFull Time
Deft Robotics
Deft Robotics: Developing AI-powered wheeled humanoid robots for manufacturing automation.
Design real-time control systems; improve IK; develop sensor fusion; integrate actuators; strong control theory; Python/C++; ROS/ROS2 preferred.
Python, C/C++, PyBullet, MuJoCo, Drake, ROS/ROS2, Kalman filtering, CAN bus
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2w
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Senior AI Engineer
San Francisco or Minneapolis or Birmingham
$134k-$180k/yr HybridFull Time
Shipt
Shipt: Provides same-day delivery services from local retailers via app.
Senior-level AI/Platform engineering experience with strong Python, cloud and container skills; experience building AI tooling, LLM integrations, observability for ML, and a bachelor's degree or equivalent.
Python, MCP, PydanticAI, LangGraph, LiteLLM, MLflow, Weights & Biases, AWS, GCP, Azure, Docker, Kubernetes
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2mo
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Senior Software Engineer
San Francisco, California, United States
HybridFull Time
Scope
Scope: Building custom AI systems and agents for enterprise workflows.
6+ YOESenior software engineer with 6+ years of production experience across frontend and backend; proficient in Python, TypeScript, React/Next.js; Docker/Kubernetes on cloud; CI/CD; and LLM frameworks.
Python, TypeScript, React, Next.js, Docker, Kubernetes, Terraform, CI/CD, LangChain, LangGraph, Anthropic SDK, OpenAI SDK, MCP, GCP, AWS
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Senior Software Engineer (Python), Mortgage
San Francisco, California, United States
$185k-$218k/yr HybridFull Time
Checkr
Checkr: AI-powered platform for background checks and identity verification.
5+ YOE5+ years software development experience, proficiency in Python and Javascript, RESTful API development, bachelor's or equivalent, strong communication, ownership, and product focus.
Python, Javascript, RESTful APIs
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2mo
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Senior Algorithms Engineer
Emeryville, California, United States
$171k-$191k/yr HybridFull Time
Eko Health
Eko Health: Develops AI-powered stethoscopes and cardiac disease detection software.
7+ YOE7+ years of experience developing and deploying signal processing algorithms and ML/DL models for embedded systems; strong Python (NumPy/SciPy) and C/C++ skills; DSP expertise; familiarity with FDA IEC 62304 and embedded ML frameworks preferred.
Python, NumPy, SciPy, PyTorch, TensorFlow, C/C++, TensorFlow Lite, Embedded inference
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1mo
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Senior Infrastructure Engineer
San Francisco, California, United States
$180k-$215k/yr OnsiteFull Time
Casca
Casca: AI-powered loan origination and processing platform for financial institutions.
5+ YOE5+ years in infrastructure, platform engineering, or SRE; strong cloud (AWS); IaC; CI/CD; programming; observability; containerization.
AWS, Terraform, CDK, Pulumi, GitHub Actions, BuildKite, Docker, Cloudflare, Python, Go, TypeScript, Rust
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1mo
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Senior Software Engineer, Data Systems (Python)
Canada or United States or San Francisco or Los Angeles
$170k-$200k/yr RemoteFull Time
Northbeam
Northbeam: Marketing intelligence and attribution platform for eCommerce brands.
5+ YOE5+ years in data/software/integration engineering; strong Python, ETL, API/REST/GraphQL/Webhooks, auth flows; SQL and BigQuery; Airflow; Docker/Kubernetes; strong problem solving and observability skills.
Python, ETL, APIs, REST, GraphQL, Webhooks, OAuth 2.0, API keys, SQL, BigQuery, Airflow, Docker, Kubernetes
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3mo
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Senior Field Engineer
Berkeley, California, United States
$120k-$140k/yr OnsiteFull Time
Ambi Robotics
Ambi Robotics: AI-powered robotic systems for e-commerce warehouse automation.
3+ YOE3+ Mgmt3+ years in field engineering or technical operations; experience leading distributed teams; travel up to 50%; hardware and software product support.
Jira Service Management, Grafana, Python, Linux, Command Line Interface
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