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289 senior software engineer python jobs at 99 companies in La Mesa, CA

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
2mo
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Senior Software Engineer
Arlington or San Diego or Woburn
$139k-$180k/yr HybridFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
5+ YOESenior software engineer with strong C++, Python/MATLAB, RT real-time systems, security clearance eligibility.
C++, Python, MATLAB, CI/CD, Windows, Linux
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2mo
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Senior Software Engineer
San Diego, California, United States
$157k-$185k/yr HybridFull Time
Faro Health
Faro Health: Software platform for clinical trial protocol design and orchestration.
7+ YOE7+ years building scalable SaaS software; microservices; TypeScript/Python/React; cloud; leadership ability; BS CS; AI/LLM integration a plus.
TypeScript, Python, React, HTML, CSS, Node.js, Docker, Azure, AWS, Google Cloud, PostgreSQL, MySQL, UV, Vite, Redis
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1mo
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Senior Software Engineer
San Diego, California, United States
OnsiteFull Time
Cohu
CohuNASDAQ: COHU: Provides semiconductor test, handling, and inspection equipment and services.
10+ YOE10+ years software engineering in automation/machine control; expert C/C++; Windows/Visual Studio; RTOS/embedded; fault handling; strong collaboration.
C++, C#, Visual Studio, RTOS, Embedded Linux, Qt, WPF, CI/CD, Jenkins, Git, Python, RS-232, RS-485, USB, Ethernet, CAN, I2C, SPI, SECS/GEM, SEMI standards
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3mo
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Senior Software Engineer
San Diego, California, United States
$115k-$140k/yr RemoteFull Time
PickTrace
PickTrace: Provides software for farm workforce and harvest management.
4+ YOE4+ years building web-based software; proficiency in Go/Kotlin/C#/Python/Java; frontend HTML/CSS/TypeScript/React; Docker; cloud deployment; AI-assisted workflows.
Docker, GitHub Copilot, Cursor, Claude
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2mo
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#Senior Software Engineer
San Diego, California, United States
$111k-$167k/yr OnsiteFull Time
Qualcomm
QualcommNASDAQ: QCOM: Designs and manufactures semiconductors and wireless telecommunications products.
1+ YOEBachelor's in CS/Engineering or related; 2+ years software engineering (or 1+ with Master's). Proficiency in C/C++, Java, Python; Linux Kernel, KVM, ARM architectures, JTAG debugging, FPGA/QEMU experience.
C, C++, Java, Python, Linux Kernel, KVM, DVFS, JTAG debuggers, FPGA, QEMU, GIT, ARMv8, ARMv9
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3mo
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Engineering - Data Platform - Senior Software Engineer
Carlsbad, California, United States
OnsiteFull Time
LightBox
LightBox: Providing data and workflow solutions for commercial real estate.
6+ YOE6+ years of software engineering; production API/microservice experience; Python/TypeScript; cloud (AWS/GCP); containers; CI/CD; developer tooling; LLM integration patterns.
Python, TypeScript, Node.js, AWS, GCP, Docker, Kubernetes, CI/CD, APIs, Microservices, OpenAI, LiteLLM, OpenRoute, AWS BedRock
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2mo
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Senior Embedded Software Engineer
San Diego, California, United States
$145k-$220k/yr OnsiteFull Time
CHAOS Industries
CHAOS Industries: Develops advanced radar and sensing systems for modern defense.
4+ YOEBachelor’s or higher in CS/CE or related; 4+ years OO software; C/C++/Python; embedded Linux with Buildroot; Linux proficiency; Agile/Scrum/CI/TD; US Person status.
C/C++, Python, Buildroot, Linux, Git, Docker, Podman, CI/CD, CUDA
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Senior Software Engineer
Carlsbad, California, United States
$130k-$180k/yr OnsiteFull Time
Nordson
NordsonNasdaq: NDSN: Manufactures precision dispensing and fluid management equipment for industry.
7+ YOEBS in Computer Science,7+ years software experience,expert C#/.NET for Windows,WPF desirable,motion systems and hardware interface experience,EM/vision knowledge and Python/C++ are a plus.
C#, .NET, WPF, C++, Python, MS Windows
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1mo
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Senior Software Engineer
Arlington or Mount Laurel or Fall River or San Diego
$114k-$273k/yr HybridFull Time
Innovative Defense Technologies
Innovative Defense Technologies: A defense technology delivering mission-critical software, automation, and systems solutions to government customers.
5+ YOESecret clearance eligibility, 5+ years software experience, Bachelor's in CS or equivalent, proficiency in C/C++, Python, Java/JavaScript, Linux, Git, SOA, DevSecOps, Agile, and experience modernizing legacy tactical systems.
C, C++, Python, JavaScript, Java, Linux, shell scripting, Git, REST, gRPC, Postgres, Make, Maven, Ant, X-Windows, MBSE, Jenkins, Jira, Atlassian, VMWare vSphere, Azure, AWS, GCP, Hadoop, Spark, Kafka, Cassandra, GitHub Copilot, ChatGPT, Claude, Cursor, Codeium, React, Angular, Vue, Storybook, TCP/IP, UDP, CORBA, DDS, DevSecOps, Service-Oriented Architecture (SOA)
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1mo
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Senior Software Engineer
San Diego, California, United States
OnsiteFull Time
ALKEME Insurance
ALKEME Insurance: Insurance brokerage and risk management services provider.
Bachelor's degree in CS/Engineering or equivalent experience; proficiency in one or more of Java, Python, C#, or JavaScript; experience with Agile/Scrum; strong problem-solving and communication skills.
Java, Python, C#, JavaScript, Agile, Scrum, AWS, Microsoft Azure, GCP
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1mo
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Senior Software Engineer
San Diego, California, United States
$150k-$185k/yr OnsiteFull Time
Satomic
Satomic: Automating chemical synthesis to accelerate small-molecule drug discovery.
5+ YOE5+ years building and operating production software; strong Python and TypeScript/React; experience with relational databases (Postgres/SQL), REST/gRPC, distributed systems, cloud (AWS/GCP/Azure), CI/CD, infrastructure-as-code, and observability.
Python, TypeScript, React, Postgres, SQL, REST, gRPC, AWS, GCP, Azure, Rust, Go, C++, CI/CD, infrastructure-as-code, message queues
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1mo
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Senior Software Engineer
Chicago or San Diego
$163k-$199k/yr OnsiteFull Time
JLL
JLLNYSE: JLL: Global commercial real estate and investment management services.
5+ YOE5+ years software development; expert in Python, Node.js, and React; experience with IaC (Terraform), cloud platforms (AWS, Microsoft Azure, GCP), containerization, CI/CD, databases, and AI-assisted development tools; Bachelor's or equivalent; US work authorization required.
Python, Node.js, Express, NestJS, React, Redux, Terraform, CloudFormation, Ansible, AWS, Microsoft Azure, GCP, GitHub Copilot, Cursor, Amazon CodeWhisperer, OpenAI Codex, Docker, Kubernetes, ECS, GraphQL, PostgreSQL, MongoDB, Jenkins, GitLab CI, GitHub Actions, Microsoft Azure DevOps, Git
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1mo
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Senior Software Engineer
San Diego, California, United States
$146k-$155k/yr OnsiteFull Time
Foresite Labs
Foresite Labs: Incubating data-driven healthcare and life sciences companies.
3+ YOEBS in CS or Engineering (5+ yrs) or MS (3+ yrs); strong C/C++ and Python; embedded and application development experience; Linux, Docker, and git proficiency; experience with CI/CD and build systems.
C/C++, Python, Linux, Docker, git, CMake, Make, CI/CD, serial, USB, Ethernet, CAN, SPI, I2C, CANopen, Modbus, EtherCAT, gRPC, MQTT
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4w
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Senior Software Engineer, Data Engineering
San Diego, California, United States
$143k-$215k/yr OnsiteFull Time
ResMed
ResMedNew York Stock Exchange: RMD: Developing cloud-connected medical devices for sleep and respiratory care.
8+ YOEBachelor's/Master's or equivalent and 8+ years software/platform engineering experience. Strong React, TypeScript/JavaScript, Python, AWS, Kubernetes, Terraform, database and CI/CD/observability experience.
React, TypeScript, JavaScript, Python, AWS, Snowflake, DynamoDB, PostgreSQL, MySQL, SQL Server, MongoDB, Kubernetes, Docker, Terraform, GitHub Actions, Datadog, Grafana, Prometheus, OpenTelemetry, CloudWatch, Kafka, Flink, Kinesis, Airflow, Dagster, Spark, Databricks, Delta Lake
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2mo
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Senior Software Engineer
San Diego, California, United States
$110k-$160k/yr OnsiteFull Time
Whova
Whova: All-in-one platform for event management and attendee engagement.
Architect backend services, frontend basics, unit testing, code reviews; Bachelor or higher; strong communication; experience with MySQL, Python, React, Redis, AWS, CI/CD.
MySQL, Python, React, Redux, Redis, AWS, CI/CD
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1w
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Software Engineer
Carlsbad, California, United States
$141k-$222k/yr HybridFull Time
Viasat
ViasatNASDAQ: VSAT: Provider of global satellite-based connectivity and secure communication solutions.
5+ YOE5+ years software engineering experience; expertise in K8s, CI/CD, Python/Ansible/Go/C, Linux and networking; strong design and troubleshooting skills; ability to travel up to 10%.
K8s, Kubernetes, Python, Ansible, Go, C, Linux, Docker, CI/CD, AWS, GCP, eBPF, AI tooling
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2w
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Senior Software Engineer
Boston or Encinitas
$142k-$192k/yr OnsiteFull Time
Paperless Parts
Paperless Parts: Cloud-based quoting software for custom part manufacturers.
5+ YOE5+ years experience building full-stack web applications; strong Python (Django/FastAPI), TypeScript/React, AWS, PostgreSQL, Docker, and CI/CD (Jenkins) experience; API design and mentoring skills; US citizenship or green card required.
Python, Django, FastAPI, TypeScript, React, PostgreSQL, AWS, Docker, Jenkins, Node/Express, Java/Spring
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1mo
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Senior Software Developer
San Diego, California, United States
$100k-$150k/yr OnsiteFull Time
The Marlin Alliance
The Marlin Alliance: Provides digital transformation and automation services to defense agencies.
Experience with React, TypeScript, and Python; strong SQL and data analysis skills; excellent communication and problem-solving; active Secret clearance required.
React, TypeScript, Python, SQL, HTML, CSS, JavaScript, C#, C, C++, Java
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2mo
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Senior AI Software Engineer
San Diego, California, United States
$115k-$160k/yr OnsiteFull Time
Accenture Federal Services
Accenture Federal ServicesNYSE: ACN: Provides technology and consulting services to U.S. federal agencies.
4+ YOE4+ years of software development; strong Linux (RHEL); experience with LLMs, AI tooling; advanced C/C++; GitLab CI/CD; Python; APIs and large-scale systems.
Red Hat Enterprise Linux, GitLab, C/C++, Python, LLMs, RAG, APIs, CI/CD
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3mo
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Senior Software Developer
Poway, California, United States
$98k-$171k/yr OnsiteFull Time
General Atomics
General Atomics: Designs and manufactures unmanned aircraft and nuclear technology systems.
3+ YOEDegree in CS/CE (or equivalent experience); C++17 and Linux experience; embedded/SoC and PetaLinux familiarity; Git, Bash, Python experience; ability to obtain DoD security clearance; 3+ years software development experience.
C++ 17, Linux, PetaLinux, x86, ARM 9, GitLab, Git, Bash, Python, Xilinx SDK
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