17 principal program manager jobs at 14 companies in Missouri

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Principal Project/Program Manager
North Carolina or Mississippi or South Carolina or Louisiana or Kentucky or Kansas or Iowa or Indiana or Arkansas or Texas or Durham or Georgia or Virginia or Tennessee or Pennsylvania or Wyoming or Michigan or Wisconsin or Maryland or Utah or Idaho or South Dakota or Florida or Oklahoma or Arizona or Ohio or Alabama or Missouri
$108k-$173k/yr RemoteFull Time
Blue Cross and Blue Shield of North Carolina
Blue Cross and Blue Shield of North Carolina: Provides health insurance and medical benefit plans to members.
8+ YOEBachelor's or advanced degree (or 10+ years' experience), 8+ years related experience, program management, budgeting, vendor management, regulatory compliance, strategic planning and evaluation.
4w
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Principal, Technical Program Manager
O'Fallon, Missouri, United States
$152k-$258k/yr OnsiteFull Time
Mastercard
MastercardNYSE: MA: Global payment processing and financial technology service provider.
Proven technical program management experience, strong leadership and communication, vendor and cloud experience, familiarity with AI best practices, strategy and execution skills, ability to deliver complex global programs.
3w
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Principal, Technical Program Management
Salt Lake City or O'Fallon
$152k-$258k/yr OnsiteFull Time
Mastercard
MastercardNYSE: MA: Global payment processing and financial technology service provider.
Proven experience leading complex, technical product and technology programs; strong stakeholder management, technical fluency, and delivery skills; Agile/hybrid/traditional methodologies; Bachelor's degree or equivalent experience preferred.
1mo
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Principal Program Manager (Bridgeton, MO, US, 63044)
Bridgeton, Missouri, United States
$131k-$177k/yr HybridFull Time
Leonardo DRS
Leonardo DRSNASDAQ: DRS: Manufactures advanced electronic systems for defense and military applications.
10+ YOEBachelor's degree or equivalent, 10+ years relevant experience, program lifecycle and earned value experience, leadership and financial management, MRP/ERP and Lean Six Sigma knowledge, PMP/DAU preferred, willingness to travel up to 20%, U.S. citizenship and active/obtainable DOD security clearance.
MRP/ERP, Lean Six Sigma, earned value management system
2mo
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Project Principal Manager
Kansas City, Missouri, United States
OnsiteFull Time
HDR
HDR: Global firm providing architecture, engineering, and environmental services.
15+ YOE7+ MgmtBachelor's in Engineering; 15+ years related experience; 7+ years PM experience; PE license; MS Office and MS Project; leadership and business development skills; active participant in employee-owned culture.
MS Office, MS Project, Access
2mo
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Project Principal Manager
Kansas City, Missouri, United States
OnsiteFull Time
HDR
HDR: Global provider of engineering, architecture, environmental and construction services.
15+ YOE7+ MgmtBachelor's in Engineering, 15 years related experience with a minimum 7 years project management experience, professional engineer (PE) license required, MS Office and Microsoft Project experience, leadership and business development skills; PMP and Master's preferred.
Microsoft Office, Microsoft Project, Microsoft Access
3mo
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Managing Principal - Building Structures
Bellevue or Des Moines or Kansas City or Los Angeles or Oklahoma City or Overland Park or St. Louis
HybridFull Time
HNTB
HNTB: Infrastructure design and engineering for transportation and public works
15+ YOEBachelor’s degree in Architecture or Engineering; 15+ years of relevant experience; leadership and business development skills.
1mo
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Principal Project Manager
St. Louis, Missouri, United States
OnsiteFull Time
Curium
Curium: Manufacturer and distributor of diagnostic and therapeutic radiopharmaceuticals.
8+ YOEBachelor's in engineering or related field (or equivalent experience), 8+ years in pharmaceutical industry leading cross-functional projects, technical pharma manufacturing knowledge, PMP preferred, strong communication and leadership skills.
Microsoft Word, PowerPoint, Microsoft Excel, Visio, MS Project, ERP
2mo
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Principal Adoption & Change Management Consultant - Remote (Saint Louis, MO, US)
Saint Louis, Missouri, United States
$129k-$170k/yr RemoteFull Time
Softchoice
Softchoice: Provides software-focused IT solutions and managed services for organizations.
15+ YOE15+ years in business advisory/IT consulting; undergraduate degree; certifications in adoption/change management; strong C-suite engagement; commercial acumen; experience in leading complex, enterprise-scale projects.
3w
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Associate Principal-Business Solutions Analyst
Chesterfield, Missouri, United States
RemoteFull Time
Mercy
Mercy: Integrated health care system providing hospital and clinical services.
12+ YOEBachelor's degree or equivalent experience, 12 years relevant technical or business experience, expertise in requirements management, process design, SDLC, and project management; strong communication and conflict-management skills.
2w
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Principal Journey Experience Owner
Durham or Alabama or Arizona or Arkansas or Colorado or Florida or Georgia or Idaho or Indiana or Iowa or Kansas or Kentucky or Louisiana or Maryland or Michigan or Mississippi or Missouri or North Carolina or Ohio or Oklahoma or Pennsylvania or South Carolina or South Dakota or Tennessee or Texas or Utah or Virginia or Wisconsin or Wyoming
$119k-$190k/yr HybridFull Time
Blue Cross and Blue Shield of North Carolina
Blue Cross and Blue Shield of North Carolina: Provides health insurance and medical benefit plans to members.
8+ YOEBachelor's degree or equivalent, 8+ years experience in customer experience/process/experience design (10+ years in lieu of degree). Lean Six Sigma Green Belt required; Black Belt preferred. Experience leading process transformation and value stream management.
Lean Six Sigma (LSS), Six Sigma, Value Stream Mapping (VSM), Value Stream Management, Waterfall Model, Root Cause Analysis (RCA)
1mo
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ArcGIS Utilities Industry Principal Director
New York City or Milwaukee or Herndon or Dallas or Columbus or Kirkland or Irvine or Cincinnati or Cleveland or Oklahoma City or Austin or Albany or Chicago or Arlington or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or Morristown or San Francisco or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$139k-$434k/yr HybridFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
10+ YOE10+ years in utility GIS solution architecture with full‑lifecycle ArcGIS Utility Network implementations; experience advising utility executives, defining enterprise GIS architecture, and leading large transformation programs; must be eligible to work in the US and willing to travel.
ArcGIS Utility Network, ArcGIS Enterprise, ArcGIS Pro, Esri
1mo
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Principal, Global Talent Hub Clinical Lead - Cigna Healthcare - Hybrid
Bloomfield or Philadelphia or Chicago or St. Louis
$142k-$236k/yr HybridFull Time
The Cigna Group
The Cigna GroupNYSE: CI: Provides health insurance and pharmacy benefit management services.
8+ YOE8+ years in healthcare clinical operations/transformation with experience in global clinical delivery models; strong regulatory/licensure knowledge; proven cross-functional leadership and experience with utilization, case management, or pharmacy support.
1w
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Principal Quantitative Genetics Process Scientist
United States or Raleigh or Chesterfield or Champaign
$127k-$191k/yr RemoteFull Time
Bayer
BayerFrankfurt Stock Exchange: BAYN: Global enterprise focused on healthcare and nutrition.
6+ YOEBachelor's in quantitative genetics/plant/animal breeding required; proficiency in R and SQL; experience developing models and workflows for breeding program design; leadership and cross-disciplinary collaboration skills; familiarity with cloud and high-performance computing.
R, SQL
2w
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Senior/Principal, Chief Systems Engineer Hypersonic Programs - Onsite
Albuquerque or Amarillo or Kansas City or Livermore
$118k-$236k/yr OnsiteFull Time
Sandia National Laboratories
Sandia National Laboratories: Conducts science and engineering research for national security.
5+ YOEBachelor's in engineering plus 5 years relevant experience (or equivalent), ability to obtain DOE Q-level security clearance, experience with avionics/missile systems, design, testing, production transition, DFX, and mentoring engineers.
3mo
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HS Trap Coach
Hollister, Missouri, United States
OnsiteFull Time
Hollister School District
Hollister School District: Provides public K-8 education services to students in California.
Must hold Missouri certification; responsible for coaching high school trap team and supporting district athletic program; applicants should complete online application and contact district athletic director or principal for questions.
2w
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Assistant HS Girls Wrestling Coach
Buffalo, Missouri, United States
OnsitePart Time, Seasonal
Dallas County R-I School District
Dallas County R-I School District: Public K-12 education and student support services provider.
Assist with high school girls wrestling program including summer weights and practice duties; season position for 2026-2027. Applicants should send a letter of interest to the Athletic Director and High School Principal.

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