41 scientific computing jobs at 28 companies in Sunnyvale, CA

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Associate Director, Scientific Computing and AI Engineer
South San Francisco, California, United States
$159k-$207k/yr OnsiteAll Commitments Available
Denali Therapeutics
Denali TherapeuticsNASDAQ: DNLI: Developing therapies to treat neurodegenerative and lysosomal storage diseases.
10+ YOE10-12 years in platform engineering/infrastructure with senior IC; expertise in HPC, cloud, AI/ML; IaC/CI/CD; Python; regulated biotech experience; leadership experience.
Slurm, LSF, GPU/CUDA, Cloud platforms, MLOps, LangChain, LangGraph, AutoGen, Python, Terraform, CI/CD
1mo
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Senior AI/ML Engineer: Python & Scientific Computing
San Francisco or New York City or United States
$175k-$250k/yr HybridFull Time
Swayable
Swayable: Measures message impact and public opinion using causal AI.
5+ YOE5+ years building scientific or quantitative data‑intensive software; expertise in scientific Python stack, object‑oriented and test‑driven development, vectorized code, machine learning, and distributed/parallel computing.
Python, NumPy, SciPy, scikit-learn, Pandas, Celery, Flask, JavaScript, Vue.js, Node.js, MongoDB, GraphQL, Linux
3w
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Software Engineer, Scientific Computing
Redwood City, California, United States
$130k-$190k/yr OnsiteFull Time
Vorticity
Vorticity: Developing specialized silicon to accelerate scientific computing beyond GPUs.
Bachelor's in math/physics/CS/engineering, strong Python skills, solid foundation in math/physics/CS, ability to work across abstraction levels and disciplines.
Python, CUDA
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HPC Scientific Support Engineer
Berkeley, California, United States
$139k-$268k/yr HybridFull Time
Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory: Conducts scientific research to address global challenges.
8+ YOE8+ years related experience with a Bachelor's (CSE3) or 12+ years (CSE4); 2+ years using HPC systems; expertise in high-performance scientific computing including at least four of Linux/Unix, Fortran, C/C++, MPI, OpenMP, OpenACC, CUDA, shell scripting, Python, parallel algorithms, debuggers, performance tools, containers; strong communication and t...
Linux/Unix, Fortran, C/C++, MPI, OpenMP, OpenACC, CUDA, shell scripting, Python, debuggers, performance tools, containers, REST, JavaScript, SQL
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Scientific and Laboratory Informatics Manager
Orlando or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or New York City or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or San Francisco or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$80k-$294k/yr OnsiteFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
6+ YOE6+ years in scientific and laboratory informatics, bachelor’s degree in life science, laboratory science, computer science or engineering, consulting experience preferred, willingness to travel up to 50% to client sites.
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Director, National Energy Research Scientific Computing Center (NERSC)
Berkeley, California, United States
$375k-$440k/yr OnsiteFull Time
Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory: Conducts multidisciplinary scientific research for the U.S. Department of Energy.
10+ YOEPh.D. and 10+ years leadership in high-performance computing, data science, or AI; strategic vision, operational and financial management, stakeholder engagement, and workforce development experience.
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Postdoctoral Appointee - Computational Mechanics, Onsite
Livermore, California, United States
OnsiteFull Time
Sandia National Laboratories
Sandia National Laboratories: Federal research and development laboratory for national security.
PhD in engineering or related field, proficiency in computational mechanics, scientific computing and software development, ability to obtain DOE Q clearance (U.S. citizenship required).
C++, Python
1w
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Postdoctoral Appointee - Computational Mechanics, Onsite
Livermore, California, United States
OnsiteFull Time, Temporary
Sandia National Laboratories
Sandia National Laboratories: Conducts science and engineering research for national security.
PhD in mechanical/civil/aerospace engineering or related, proficiency in computational mechanics, scientific computing and software development, ability to obtain DOE Q clearance (U.S. citizenship required).
C++, Python
2w
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Research Scientist, Life Sciences (Computational)
San Francisco, California, United States
$300k-$320k/yr HybridFull Time
Anthropic
Anthropic: Developing safe and reliable artificial intelligence systems.
PhD or equivalent industry research experience in computational biology or related field; track record of end-to-end computational biology research; proficiency with Linux, cloud compute, and scientific programming; strong communication with biologists and ML researchers.
Claude, Linux
5d
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Senior Manager, Research Informatics
Redwood City, California, United States
$164k-$205k/yr HybridFull Time
Revolution Medicines
Revolution MedicinesNASDAQ: RVMD: Developing precision oncology therapies for RAS-addicted cancers
7+ YOEBachelor's in scientific/computational field,7+ years leading research informatics or scientific applications,experience with assay management platforms,SQL and Python proficiency,people leadership and program management skills.
Genedata Screener, Benchling, Genedata Expressionist, D360, Mosaic, IDBS ActivityBase, Revvity Signals, SQL, Python
4d
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Member of Technical Staff - Applied Computational Biologist
New York City or San Francisco
OnsiteFull Time
Valthos
Valthos: Develops AI systems to identify biological threats and design countermeasures.
Extensive computational biology research experience, strong scientific communication, ability to analyze biological data, proficiency in Python, and ability to work on-site in New York City or San Francisco.
Python
2d
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Applied AI Scientist, Technology Partnerships (Senior/Principal)
San Francisco, California, United States
$200k-$300k/yr OnsiteFull Time
Sygaldry
Sygaldry: Building quantum-accelerated servers for efficient AI model training.
Advanced computational background (MS/PhD preferred) with strong Python and scientific computing, generative modeling and benchmarking experience, ability to prototype and validate methods in partner domains.
Python
2mo
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Junior/Assistant Specialist - Energy Decomposition Analysis (EDA) / M. Head-Gordon Group - Dept. of Chemistry
Berkeley, California, United States
$57k-$66k/yr OnsitePart Time
University of California
University of California: A public research university system providing education and healthcare.
Bachelor's degree required; coding in Python and C++; experience with data analysis and scientific computing; authorized to work in the U.S.; no visa sponsorship.
Python, C++, Microsoft Word, Microsoft Excel, Microsoft PowerPoint
3w
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Research Scientist - Quantum Chemistry - Global Frontier Tech Recruitment Program - 2027 Start (PhD)
San Jose, California, United States
OnsiteFull Time
ByteDance
ByteDance: Developing AI-driven content platforms and mobile applications.
PhD in CS, ML, Physics, Chemistry, Math or related; strong math and programming skills; independent research ability; interest in AI and scientific computing.
1mo
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Scientist II, Translational Research
Redwood City or Boston or New York City or Chicago or California or Colorado or Illinois or New York
$90k-$150k/yr OnsiteFull Time
Tempus AI
Tempus AINASDAQ: TEM: Builds a data platform for AI-powered precision medicine diagnostics.
4+ YOEPhD preferred; 4+ years drug development experience using genomic and multimodal data; strong computational biology and AI skills; client-facing experience; proficiency in R, Python, and scientific computing tools.
R, Python, SQ, Pandas, NumPy, SciPy, Scikit-learn, Jupyter Notebooks, RStudio, tidyverse, ggplot, Git, matplotlib, seaborn, HTML5, CSS3, JavaScript, D3, Plot.ly, Flask, Dask, Docker, AWS
1mo
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Software/Algorithm Engineer
Santa Clara, California, United States
$152k-$209k/yr OnsiteFull Time
Applied Materials
Applied MaterialsNASDAQ: AMAT: Produces equipment and services for chip and display manufacturing.
MS or higher in a related field; strong optical physics, wave-optics modeling, image processing and computer vision; proficiency in Python, MATLAB or C/C++; experience with scientific computing libraries and strong analytical skills.
Python, MATLAB, C/C++
2mo
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Founding Engineer
San Francisco, California, United States
$175k-$225k/yr OnsiteFull Time
Clera
Clera: AI talent agent matching professionals with high-growth startup roles
2+ YOEComputer Science degree required, 2+ years professional software engineering experience, strong CS fundamentals, startup experience valued, proficiency in Python (typed scientific Python).
Python
2w
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Process Engineer 2
Fremont, California, United States
OnsiteFull Time
Lam Research
Lam ResearchNASDAQ: LRCX: Manufacturing equipment used to fabricate advanced semiconductor microchips.
Graduate-eligible process engineer versed in materials/chemical engineering and semiconductor processing; experience with lab work, SPC/DOE, statistical analysis, and scientific computing (MATLAB/Python).
MATLAB, Python, JMP, Minitab
2w
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Senior ML Scientist, Biological Systems
San Francisco, California, United States
$268k-$336k/yr OnsiteFull Time
Lila Sciences
Lila Sciences: Develops an AI platform for autonomous scientific research and discovery.
PhD in ML, CS, computational biology or related; strong ML research record; experience with PyTorch/JAX/TensorFlow; expertise in scientific reasoning, experimental design, and probabilistic modeling preferred.
PyTorch, JAX, TensorFlow
1mo
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Senior Staff Scienitst-Quantitative Modeling, AI & Pharmacometrics
San Francisco, California, United States
OnsiteFull Time
UCSF Health
UCSF Health: Academic medical center providing advanced patient care and research.
5+ YOEBachelor's in computational/data science or domain science with computational focus; 5+ years relevant experience; advanced pharmacometrics/MIDD knowledge; Python and/or R programming; experience with mechanistic, PK/PD, Bayesian or ML models; scientific leadership and communication skills.
Python, R