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8,117 senior python developer jobs at 1,696 companies in California

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
1mo
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Python Developer 6254661
Charlotte or Cleveland or California or Colorado or District of Columbia or Illinois or Maryland or Massachusetts or Minnesota or New York or New Jersey or Washington
$24-$72/hr OnsiteFull Time, Contract
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
5+ YOE5+ years Python development, 3+ years Oracle SQL and banking/finance domain experience. Proficiency with React JS, Django/Flask, UNIX/shell scripting, relational databases (Sybase/Oracle), Git/Mercurial/SVN, and strong unit testing and debugging skills. Associate's degree required.
React JS, Python, JS, Django, Flask, UNIX, shell scripting, SQL, Oracle, Sybase, Oracle SQL, ORM libraries, Git, Mercurial, SVN
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1mo
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Principal Python Engineer (Modeling & Simulation)
San Francisco or Boston or United States
HybridFull Time
Code Metal
Code Metal: Verifiable AI-powered code translation for mission-critical industries.
7+ YOE7+ years Python software development, experience with scalable APIs, Docker, cloud distributed systems, stakeholder-driven design, SDLC best practices; eligible for U.S. Top Secret clearance.
Python, Docker, REST, GraphQL, gRPC, AWS, GCP, Azure
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Python/Django Developer
San Jose, California, United States
$64k-$140k/yr OnsiteFull Time
Tata Consultancy Services
Tata Consultancy ServicesNational Stock Exchange of India: TCS: Global provider of IT services, consulting, and business solutions.
10+ YOEU.S. citizenship required for federal work; 10+ years software engineering with 5+ years Python; experience with Django and Nginx; AWS Gov cloud, FedRAMP/IL5 and security-clearance capability preferred.
Python, Django, Nginx, AWS Gov cloud, AWS
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2mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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3mo
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Senior Software Engineer - Python
San Jose or Austin
$144k-$213k/yr HybridFull Time
PayPal
PayPalNASDAQ: PYPL: Digital platform for sending money and processing online payments.
3+ YOE3+ years Python backend experience; Bachelor's degree or equivalent; Django/Flask; SOA; REST/Web services; Git; cloud familiarity; SQL/NoSQL; CI/CD; distributed systems.
Python, Django, Flask, Git, AWS, GCP, Azure, Terraform, SQL, NoSQL, Redis, SQS, Kafka, CI/CD, Observability
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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1mo
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Python Test Automation Engineer
Los Angeles, California, United States
$140k-$150k/yr OnsiteFull Time
EPAM Systems
EPAM SystemsNYSE: EPAM: Provides global digital platform engineering and software development services.
Bachelor's in a relevant engineering or CS field; proven experience building Python-based test automation frameworks, robotic automation fixtures integration, Git/GitHub/GitLab, UNIX, and Jenkins; sensor validation experience; Master's degree preferred.
Python, UNIX, Jenkins, Git, GitHub, GitLab, CI/CD, Anthropic Claude, Claude Code, LinkedIn Learning
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1mo
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Senior Professional Software Engineer (Python)
Irvine or Oklahoma City or Sunrise or Oxford or Dallas or Austin
$129k-$165k/yr HybridFull Time
Cotality
Cotality: Provider of property intelligence, data, and analytics solutions.
5+ YOEBachelor's or Master's in Computer Science/AI or related, 5+ years software engineering, expert Python/FastAPI, microservices, Snowflake/Databricks, cloud (GCP/AWS/Azure), Agile (Jira/Confluence), strong communication and mentoring skills.
Python, FastAPI, Snowflake, Databricks, GCP, AWS, Azure, Jira, Confluence, YAML
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2mo
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Senior Software Engineer, Developer Experience
Bellevue or Livingston or New York or San Francisco or Sunnyvale
$165k-$242k/yr HybridFull Time
CoreWeave
CoreWeaveNASDAQ: CRWV: Cloud platform providing GPU-accelerated infrastructure for AI workloads.
7+ YOESenior software engineer with 7+ years in production platforms, distributed systems, and developer tooling.
Go, Python, Kubernetes, GitHub Actions, Buildkite, Bazel, Artifactory, MCP
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1mo
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
Tyba
Tyba: AI software for modeling and operating renewable energy projects.
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
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2mo
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Senior Software Engineer
Arlington or San Diego or Woburn
$139k-$180k/yr HybridFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
5+ YOESenior software engineer with strong C++, Python/MATLAB, RT real-time systems, security clearance eligibility.
C++, Python, MATLAB, CI/CD, Windows, Linux
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Senior Software Engineer (Python)
Denver or San Francisco or Nashville or Santiago
HybridFull Time
Checkr
Checkr: AI-powered platform for background checks and identity verification.
Experienced software engineer to build and maintain Checkr's data platform and AI verification systems; role expects in-office collaboration at hub locations.
Python
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2mo
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Senior Backend Engineer (Python) - Content Understanding
San Francisco or Atlanta or Austin or Boston or Chicago or Dallas or Denver or Houston or Jacksonville or Los Angeles or Miami or New York City or Phoenix or Portland or Sacramento or Salt Lake City or San Diego or Seattle or Washington, D.C. or Ottawa or Toronto or Vancouver or Mexico City
$120k-$228k/yr HybridFull Time
Scribd
Scribd: Subscription-based digital library for e-books, audiobooks, and documents.
7+ YOE7+ years software engineering; Python 5+ years; distributed systems; AWS; Terraform; leadership; bachelor’s in CS.
Python, Scala, Airflow, Spark, Databricks, Terraform, AWS, SQS, SNS, CloudWatch, Datadog
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3mo
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Senior Software Engineer - Python
San Jose or Austin
$144k-$213k/yr HybridFull Time
PayPal
PayPalNASDAQ: PYPL: Global digital payments platform for consumers and merchants.
3+ YOE3+ years relevant experience and bachelor’s degree or equivalent; strong Python backend skills (Django/Flask), data structures, web services, Git, cloud (AWS/GCP/Azure), Terraform, SQL/NoSQL, Redis, messaging systems, CI/CD, testing, and observability.
Python, Django, Flask, Git, AWS, GCP, Azure, Terraform, SQL, NoSQL, Redis, SQS, SNS, Kafka, RabbitMQ, Pulsar, CI/CD
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3mo
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Senior Software Engineer - Python Numerical Computing Libraries
Santa Clara or United States
$184k-$357k/yr HybridFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Designs graphics processing units and artificial intelligence hardware.
6+ YOE6+ years industry experience; strong Python, C++, and CUDA skills; deep knowledge of numerical methods and Python numerical libraries; experience with parallel programming, performance analysis, and publishing Python libraries.
Python, C++, CUDA, NumPy, SciPy, CuPy, Jax.NumPy, NumS, cuNumeric, Pandas, scikit-learn, TensorFlow, PyTorch
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2mo
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Senior Software Engineer
San Francisco, California, United States
$180k-$215k/yr OnsiteFull Time
HeartFlow
HeartFlowNASDAQ: HTFL: Provides AI-driven non-invasive cardiac diagnostic software and analysis.
3+ YOESenior Software Engineer with strong Python, AWS, Django/JS, TypeScript, CI/CD, and experience building cloud-native APIs and web applications in regulated environments.
Python, AWS, Django, JavaScript, TypeScript, Nginx, Pytest, GitHub, GitHub Actions, Kubernetes, CDK, Step Functions, Lambdas, API Gateway, Fargate, ECS, Aurora
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1mo
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Senior AI/ML Engineer: Python & Scientific Computing
San Francisco or New York City or United States
$175k-$250k/yr HybridFull Time
Swayable
Swayable: Measures message impact and public opinion using causal AI.
5+ YOE5+ years building scientific or quantitative data‑intensive software; expertise in scientific Python stack, object‑oriented and test‑driven development, vectorized code, machine learning, and distributed/parallel computing.
Python, NumPy, SciPy, scikit-learn, Pandas, Celery, Flask, JavaScript, Vue.js, Node.js, MongoDB, GraphQL, Linux
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1mo
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Senior Software Engineer
Sunnyvale, California, United States
$160k-$185k/yr OnsiteFull Time
LTA Research & Exploration
LTA Research & Exploration: Develops and builds next-generation zero-emission rigid airships.
7+ YOE7-5 years of experience in a similar Senior Software Engineer role; proficient in RTOS, embedded systems, C#, C++, Python; GitLab CI/CD; strong communication.
C#, C++, RTOS, Python, Scripting, GitLab CI/CD
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2mo
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Senior Software Engineer, AI
El Segundo or United States
$153k-$170k/yr RemoteFull Time
ImmunityBio
ImmunityBioNASDAQ: IBRX: Develops next-generation immunotherapies for cancer and infectious diseases.
7+ YOESenior software engineer with 7+ years of experience in Python/Typescript, AI agent frameworks, and production-grade systems.
Python, TypeScript, FastAPI, Docker, LangGraph, LangChain, CrewAI, LlamaIndex, Chroma, Milvus, Weaviate, Qdrant
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2mo
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Senior Software Engineer
San Francisco, California, United States
HybridFull Time
Scope
Scope: Building custom AI systems and agents for enterprise workflows.
6+ YOESenior software engineer with 6+ years of production experience across frontend and backend; proficient in Python, TypeScript, React/Next.js; Docker/Kubernetes on cloud; CI/CD; and LLM frameworks.
Python, TypeScript, React, Next.js, Docker, Kubernetes, Terraform, CI/CD, LangChain, LangGraph, Anthropic SDK, OpenAI SDK, MCP, GCP, AWS
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