3,320 senior python developer jobs at 960 companies in Fairfax, CA
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Senior Software Engineer - Python
Raleigh or San Francisco
$110k-$270k/yr RemoteFull Time
5+ YOE5+ years software development with production-level Python; experience building high-scale enterprise SaaS cloud applications; proven scalability and architecture skills; hands-on with Python, Git, FastAPI, Pydantic; strong communication and mentorship; unrestricted US work authorization.
Python, Git, FastAPI, Pydantic
2mo
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Principal Python Engineer (Modeling & Simulation)
San Francisco or Boston or United States
HybridFull Time
7+ YOE7+ years Python software development, experience with scalable APIs, Docker, cloud distributed systems, stakeholder-driven design, SDLC best practices; eligible for U.S. Top Secret clearance.
Python, Docker, REST, GraphQL, gRPC, AWS, GCP, Azure
3mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
2mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
3mo
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Senior Software Engineer, Developer Experience
Bellevue or Livingston or New York or San Francisco or Sunnyvale
$165k-$242k/yr HybridFull Time
7+ YOESenior software engineer with 7+ years in production platforms, distributed systems, and developer tooling.
Go, Python, Kubernetes, GitHub Actions, Buildkite, Bazel, Artifactory, MCP
2mo
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
5d
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Senior Software Engineer (Python), Mortgage
San Francisco, California, United States
$185k-$218k/yr HybridFull Time
5+ YOE5+ years software development, bachelor or equivalent, proficiency in Python and Javascript, RESTful API experience, strong communication and ownership.
Python, Javascript, RESTful APIs
3mo
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Senior Software Engineer
San Francisco, California, United States
HybridFull Time
6+ YOESenior software engineer with 6+ years of production experience across frontend and backend; proficient in Python, TypeScript, React/Next.js; Docker/Kubernetes on cloud; CI/CD; and LLM frameworks.
Python, TypeScript, React, Next.js, Docker, Kubernetes, Terraform, CI/CD, LangChain, LangGraph, Anthropic SDK, OpenAI SDK, MCP, GCP, AWS
2mo
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Senior AI/ML Engineer: Python & Scientific Computing
San Francisco or New York City or United States
$175k-$250k/yr HybridFull Time
5+ YOE5+ years building scientific or quantitative data‑intensive software; expertise in scientific Python stack, object‑oriented and test‑driven development, vectorized code, machine learning, and distributed/parallel computing.
Python, NumPy, SciPy, scikit-learn, Pandas, Celery, Flask, JavaScript, Vue.js, Node.js, MongoDB, GraphQL, Linux
2w
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Senior Software Engineer - Python/Agentic AI
Pleasanton, California, United States
$170k-$213k/yr HybridFull Time
3+ YOEBS+5 years or MS+3 years in computer science; experience with Python/C#/Java and building SaaS/REST APIs; strong CS fundamentals, SQL, distributed systems, cloud and on-call experience.
C#, Java, Python, .NET, .NET Core, HTML, JavaScript, CSS, SQL, PostgreSQL, NoSQL, Docker, Kubernetes, Kafka, SQS, RabbitMQ, Azure, ASW, GCP
2mo
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Senior Software Engineer
Los Angeles or Washington or San Francisco or San Diego or Seattle or London
$130k-$220k/yr OnsiteFull Time
3+ YOE3+ years software development; strong Python; Azure cloud; on-call production support; must be a U.S. Person; ability to obtain security clearance.
Python, Azure, Git, CI/CD, Docker, Kubernetes, TypeScript, Java, Bash, Rust, Node.js
2mo
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Senior Staff, Software Engineer
Palo Alto or United States
$185k-$260k/yr HybridFull Time
10+ YOESenior-level software engineer with cloud, Python and a compiled language, life sciences exposure, and leadership experience.
Python, Rust, Java, C++, C#, AWS, Jira, Git, CI/CD
2mo
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Senior Backend Engineer, Agentic
Palo Alto, California, United States
$350k-$500k/yr OnsiteFull Time
10+ YOESenior backend engineer with 10+ years in production cloud systems; strong Python, PostgreSQL, Redis; cloud experience (AWS/GCP/Azure); Kubernetes; LLM patterns; ownership and reliability.
Python, PostgreSQL, Redis, Kubernetes, Docker, Cloud Platform (AWS/GCP/Azure), LangGraph, LlamaIndex, OpenAI
2mo
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Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes)
San Francisco or Cambridge or McLean or New York or San Jose
$230k-$286k/yr HybridFull Time
6+ YOE1+ MgmtBachelor’s degree; 6+ years software engineering; 1+ year cloud experience; 9+ years in Python/Golang/Node.js; 4+ years cloud services; 4+ years open source frameworks; 2+ years Kubernetes; 1+ year people management; 2+ years ML platform experience
Golang, Python, JavaScript, Java, TypeScript, SQL, HTML, CSS, Docker, Kubernetes, AWS, GCP, Azure, NoSQL, RDBMS
2mo
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Senior Software Engineer - Marketplace
San Mateo, California, United States
$197k-$295k/yr OnsiteFull Time
3+ YOE3+ years software development; proficient in C#, Go, Rust, Java, C++, or Python; REST/GRPC; scalable microservices; Bachelor's in CS/CE or equivalent.
C#, Go, Rust, Java, C++, Python, REST, gRPC, API design patterns, Containerization, Microservices
2mo
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Senior Software Engineer - Cloud Gateway
Palo Alto or Vancouver
$132k-$165k/yr HybridFull Time
2+ YOESenior software engineer with a Bachelor’s degree and at least 2 years of distributed-systems experience; proficient in Go/Rust/Python; AWS; Kafka; Redis; databases; CI/CD; Git; able to work hybrid from Palo Alto or remote.
Go, Rust, Python, AWS, Kafka, Redis, DynamoDB, RDS, DocumentDB, MongoDB, Datadog, CloudWatch, Terraform, Kubernetes, Docker, Git
2mo
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Senior Software Development Engineer, Platform
San Mateo, California, United States
$150k-$165k/yr HybridFull Time
Proficient in Java with Scala and Python; backend development; cloud SaaS; Kubernetes; GitHub workflows; Spring ecosystem; AI tooling; strong problem-solving and communication.
Java, Scala, Python, Kubernetes, GitHub, Spring, Spring Boot, Spring Security, GitHub Actions, GitHub Copilot
2mo
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Senior Full Stack Developer
San Francisco, California, United States
$150k-$250k/yr OnsiteFull Time
4+ YOE4+ years of full-stack development; strong frontend with React, Vue, or Svelte and TypeScript; backend with Node.js, Python, or Go; REST/GraphQL; relational DBs; cloud deployment (AWS, GCP, or Azure); independent in a fast-paced, cross-functional environment.
React, Vue, Svelte, TypeScript, Node.js, Python, Go, REST, GraphQL, AWS, GCP, Azure, Databases, Docker, Kubernetes
3mo
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Senior Software Engineer
San Francisco or New York City
$180k-$230k/yr HybridFull Time
Proficient in TypeScript (React) and Python (Flask); AI-native workflow experience; experience with SQL/Postgres; startup experience; strong customer focus.
React, TypeScript, Python, Flask, Firebase, SQL, PostgreSQL
2mo
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Senior Engineer, Server – NBA 2K
Novato, California, United States
$131k-$174k/yr RemoteFull Time
5+ YOE5+ years backend experience; strong C++; Python or similar scripting; distributed systems; multithreading; database optimization.
C++, Python, SQL, MySQL, Microsoft SQL Server, PHP, Perl, Ruby
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