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2,196 senior python developer jobs at 750 companies in Napa, CA

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
1mo
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Principal Python Engineer (Modeling & Simulation)
San Francisco or Boston or United States
HybridFull Time
Code Metal
Code Metal: Verifiable AI-powered code translation for mission-critical industries.
7+ YOE7+ years Python software development, experience with scalable APIs, Docker, cloud distributed systems, stakeholder-driven design, SDLC best practices; eligible for U.S. Top Secret clearance.
Python, Docker, REST, GraphQL, gRPC, AWS, GCP, Azure
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2mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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2mo
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Senior Software Engineer, Developer Experience
Bellevue or Livingston or New York or San Francisco or Sunnyvale
$165k-$242k/yr HybridFull Time
CoreWeave
CoreWeaveNASDAQ: CRWV: Cloud platform providing GPU-accelerated infrastructure for AI workloads.
7+ YOESenior software engineer with 7+ years in production platforms, distributed systems, and developer tooling.
Go, Python, Kubernetes, GitHub Actions, Buildkite, Bazel, Artifactory, MCP
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1mo
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
Tyba
Tyba: AI software for modeling and operating renewable energy projects.
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
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Senior Software Engineer (Python)
Denver or San Francisco or Nashville or Santiago
HybridFull Time
Checkr
Checkr: AI-powered platform for background checks and identity verification.
Experienced software engineer to build and maintain Checkr's data platform and AI verification systems; role expects in-office collaboration at hub locations.
Python
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2mo
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Senior Backend Engineer (Python) - Content Understanding
San Francisco or Atlanta or Austin or Boston or Chicago or Dallas or Denver or Houston or Jacksonville or Los Angeles or Miami or New York City or Phoenix or Portland or Sacramento or Salt Lake City or San Diego or Seattle or Washington, D.C. or Ottawa or Toronto or Vancouver or Mexico City
$120k-$228k/yr HybridFull Time
Scribd
Scribd: Subscription-based digital library for e-books, audiobooks, and documents.
7+ YOE7+ years software engineering; Python 5+ years; distributed systems; AWS; Terraform; leadership; bachelor’s in CS.
Python, Scala, Airflow, Spark, Databricks, Terraform, AWS, SQS, SNS, CloudWatch, Datadog
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Senior AI/ML Engineer: Python & Scientific Computing
San Francisco or New York City or United States
$175k-$250k/yr HybridFull Time
Swayable
Swayable: Measures message impact and public opinion using causal AI.
5+ YOE5+ years building scientific or quantitative data‑intensive software; expertise in scientific Python stack, object‑oriented and test‑driven development, vectorized code, machine learning, and distributed/parallel computing.
Python, NumPy, SciPy, scikit-learn, Pandas, Celery, Flask, JavaScript, Vue.js, Node.js, MongoDB, GraphQL, Linux
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2mo
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Senior Software Engineer
San Francisco, California, United States
$180k-$215k/yr OnsiteFull Time
HeartFlow
HeartFlowNASDAQ: HTFL: Provides AI-driven non-invasive cardiac diagnostic software and analysis.
3+ YOESenior Software Engineer with strong Python, AWS, Django/JS, TypeScript, CI/CD, and experience building cloud-native APIs and web applications in regulated environments.
Python, AWS, Django, JavaScript, TypeScript, Nginx, Pytest, GitHub, GitHub Actions, Kubernetes, CDK, Step Functions, Lambdas, API Gateway, Fargate, ECS, Aurora
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2mo
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Senior Software Engineer
San Francisco, California, United States
HybridFull Time
Scope
Scope: Building custom AI systems and agents for enterprise workflows.
6+ YOESenior software engineer with 6+ years of production experience across frontend and backend; proficient in Python, TypeScript, React/Next.js; Docker/Kubernetes on cloud; CI/CD; and LLM frameworks.
Python, TypeScript, React, Next.js, Docker, Kubernetes, Terraform, CI/CD, LangChain, LangGraph, Anthropic SDK, OpenAI SDK, MCP, GCP, AWS
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2mo
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Senior Software Engineer
Nashville or San Francisco
HybridFull Time
Asurion: Provides insurance and repair services for consumer electronics.
3+ YOESenior full-stack engineer with 3+ years cloud web app experience; Node.js/React/TypeScript and/or Python; Kafka, MongoDB, Redis; strong CS fundamentals; hybrid work in the US.
Node.js, React, TypeScript, Python, Kafka, MongoDB, Redis
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2mo
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Senior Software Engineer
Minneapolis or San Francisco or Birmingham or United States or Minneapolis
HybridFull Time
Shipt
Shipt: Provides same-day delivery services from local retailers via app.
5+ YOE5+ years of software development; backend REST APIs; Golang or Python; SQL databases (Postgres); scalable architectures; on-call readiness; strong communication.
Go, Python, Kafka, PostgreSQL, Redis, Apache Kafka, Google Cloud Platform, Microservices
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2mo
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Senior Software Engineer
San Francisco, California, United States
$117k-$209k/yr HybridFull Time
Autodesk
AutodeskNASDAQ: ADSK: Developing software for architecture, engineering, and entertainment industries.
5+ YOE5–8 years software development; Java/Node.js/Python; React.js; AWS; RESTful APIs; SQL/NoSQL; Agile/Scrum; excellent communication.
Java, Node.js, Python, React.js, AWS, REST, SQL, NoSQL, Kafka, Flink, Spark
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1mo
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Senior Software Engineer
Los Angeles or Washington or San Francisco or San Diego or Seattle or London
$130k-$220k/yr OnsiteFull Time
CHAOS Industries
CHAOS Industries: Develops advanced radar and sensing systems for modern defense.
3+ YOE3+ years software development; strong Python; Azure cloud; on-call production support; must be a U.S. Person; ability to obtain security clearance.
Python, Azure, Git, CI/CD, Docker, Kubernetes, TypeScript, Java, Bash, Rust, Node.js
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2mo
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Senior DevTools Engineer
San Francisco or Boston or New York or Denver
$163k-$247k/yr HybridFull Time
Semgrep
Semgrep: Provides a code security platform for developers and security teams.
5+ YOE5+ years software engineering; experience in developer tooling, software/infrastructure engineering; cloud infrastructure design and deployment; Python and TypeScript proficiency; security-aware mindset.
Python, TypeScript, AWS, GCP, Cloud infrastructure, Developer tooling
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3mo
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Senior Software Engineer
San Francisco, California, United States
$195k-$230k/yr HybridFull Time
Collective
Collective: All-in-one financial platform for self-employed entrepreneurs.
5+ YOE5+ years in production software, strong full-stack skills (Python, Django, React), ownership of features end-to-end, experience with AI developer tools, ability to ship solutions from problem to product.
Python, Django, React, AI tools, Copilots, Code agents
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1mo
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Senior Software Developer
Benicia, California, United States
$112k-$154k/yr OnsiteFull Time
Applied Materials
Applied MaterialsNASDAQ: AMAT: Produces equipment and services for chip and display manufacturing.
Senior software engineer with backend focus, strong C#/.NET, distributed systems, and testing; MATLAB scripting and automation mentioned.
C#, NET, NET Core, gRPC, TCP/IP, Windows, Jenkins, Bitbucket, Git, Jira, Confluence, Python
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1mo
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Senior Software Engineer
San Francisco, California, United States
RemoteFull Time
Rebound Health
Rebound Health: Provides virtual, evidence-based psychotherapy for trauma and PTSD.
6+ YOE6+ years software development; 4+ years full-stack web apps; Python backend; TypeScript familiarity; REST APIs and microservices; AWS (S3, EC2, RDS/Aurora); MySQL; CI/CD; testing; strong communication.
Python, TypeScript, AWS, REST API, Microservices, MySQL, GitHub, CI/CD
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3mo
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Senior Software Engineer - Search
San Francisco, California, United States
$158k-$238k/yr HybridFull Time
Hinge Health
Hinge HealthNYSE: HNGE: Digital provider of musculoskeletal care and physical therapy
5+ YOE5+ years software development; 3+ years Elasticsearch/OpenSearch; geospatial search and entity resolution; backend languages (Golang, Python, Java); cloud services (AWS, Docker/Kubernetes).
Elasticsearch, OpenSearch, Golang, Python, Java, AWS, Docker, Kubernetes
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3mo
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Senior Software Engineer, Post-Trade Financial Systems
Berkeley or United States
$225k-$255k/yr HybridFull Time
The Voleon Group
The Voleon Group: Quantitative investment management firm using machine learning strategies.
5+ YOESenior Software Engineer with 5+ years, Python, large-scale systems, cross-functional collaboration, mentorship.
Python, Airflow, Go, Apache Beam, pandas, polars, dask, duckdb
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