36 senior python developer jobs at 21 companies in Winnsboro, SC

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
1mo
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Senior API Engineer (Python / AWS)
Fort Mill or Charlotte or Austin
$106k-$177k/yr HybridFull Time
LPL Financial
LPL FinancialNASDAQ: LPLA: Provides wealth management and brokerage services to financial advisors.
7+ YOE7+ years in software/API/cloud development; Python API development; AWS Lambda/API Gateway; Terraform; CI/CD; production support.
Python, AWS, Terraform, OAuth2, JWT, IAM, Amazon API Gateway, AWS Lambda, CloudWatch, OpenTelemetry
1mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
2mo
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Senior Software Engineer I
Fort Mill or Tempe
HybridFull Time
Shutterfly
Shutterfly: Manufacturer and retailer of personalized photo products and professional photography services.
6+ YOE6+ years in application development; Java, Spring Boot, Python; 3+ years AWS; driven to build scalable systems; experience with Agile and CI/CD; mentorship capabilities.
Java, Spring Boot, Python, AWS, React, Angular, RabbitMQ, GraphQL, Terraform, REST
17h
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Senior Software Engineer, Golang
Charlotte or Fort Mill or Denver or Minneapolis
$119k-$150k/yr HybridFull Time
RVO Health
RVO Health: Provides digital health information and consumer wellness solutions.
5+ YOEBachelor's or equivalent,5+ years software development experience,proficiency in Go and multiple languages,experience with testing,AWS and IaC preferred,strong problem-solving and communication skills.
Golang, Go, PHP, JavaScript, Python, TypeScript, Java, C#, C++, Node.js, GraphQL, REST APIs, NoSQL, AWS, IaC
4d
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Senior Software Engineer Applied AI
Columbia or United States
RemoteFull Time
AMC Health
AMC Health: Provides remote patient monitoring and virtual care technology.
7+ YOE7+ years building production backend systems, strong Python, cloud/distributed systems experience, hands-on LLM/generative AI, ML lifecycle proficiency, and disciplined work in regulated environments.
Python, AWS, LLMs
3w
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Software Engineer
Fort Mill, South Carolina, United States
$86k-$118k/yr HybridFull Time
Sunbelt Rentals
Sunbelt RentalsNYSE: SUNB: Renting construction, industrial, and specialty equipment and tools.
5+ YOEBachelor's in Computer Science or equivalent plus 5+ years developing RPGLE/RPG-FREE on IBM Power Systems; experience with web services/REST/JSON, change management tools (Aldon); Python and Help Systems products are a plus.
HTML5, Node.js, React, JavaScript, IBM Power System, RPGLE, RPG-FREE, RPGFREE, Aldon, JSON, REST APIs, Python, CL, Webservices, XML, Help Systems
1w
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Senior Infrastructure Engineer
Glen Allen or Richmond or Columbia
$91k-$118k/yr HybridFull Time
Dominion Energy
Dominion EnergyNYSE: D: Provides regulated electric and natural gas utility services.
5+ YOE5+ years enterprise storage administration experience; hands-on with Hitachi VSP/GAD, Brocade Fibre Channel, NetApp ONTAP, HCP; compliance experience (NERC CIP, SOX, DoD); scripting/automation (PowerShell, Python).
Hitachi VSP, Global-Active Device (GAD), Brocade Fibre Channel, NetApp (ONTAP), Hitachi Content Platform (HCP), Rubrik, VMware (vSphere/VCF), OpenShift, Ansible, Terraform, PowerShell, Python, Azure, AWS
2mo
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Lead Software Engineer (Hybrid)
Hartford or Charlotte or Short Hills
$130k-$176k/yr HybridFull Time
Selective Insurance
Selective InsuranceNASDAQ: SIGI: Provider of commercial and personal property and casualty insurance.
7+ YOESenior software engineer with .NET (C#, ASP.NET Core), Azure, AI, microservices, DevOps, and leadership experience.
C#, ASP.NET Core, Azure, Azure AI Services, REST, GraphQL, Docker, Kubernetes, Terraform, Bicep, ARM, CI/CD, DevOps, Terraform, Cloud, SAFe, Pega, Python, TensorFlow, PyTorch, Camunda, Appian, Angular, React, Kafka, RabbitMQ
1mo
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Nuclear Engineer III/Senior Nuclear Engineer – Safety Analysis Applications
Charlotte or Huntersville or York
HybridFull Time
Duke Energy
Duke EnergyNYSE: DUK: Provides electric and natural gas services to customers.
4+ YOEABET-accredited engineering degree required (Master's may be considered), 4+ years engineering experience (6+ for senior), minimum 1 year nuclear experience, strong thermal-hydraulics and safety analysis skills, ability to achieve nuclear site unescorted access.
RETRAN, RELAP, GOTHIC, Unix, Linux, FORTRAN, Python, VBA
2w
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Principal Software Engineer - Software Architect
Charlotte or Hartford
$130k-$190k/yr OnsiteFull Time
Talcott Financial Group
Talcott Financial Group: International life insurance group providing risk and retirement solutions.
10+ YOE5+ Mgmt10+ years software engineering, 5+ years architecture; deep Microsoft Azure and AI/ML experience; proficiency with C#, Python, SQL, Terraform/Bicep/ARM, CI/CD, and enterprise data platforms.
Azure, Microsoft Fabric, C#, Python, SQL, Terraform, Bicep, ARM templates, CI/CD
1mo
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Senior Software Development Engineer in Test
Charlotte or Fort Mill
HybridFull Time
EPAM Systems
EPAM SystemsNYSE: EPAM: Provides global digital platform engineering and software development services.
Strong AWS and serverless engineering, Python 3 proficiency, UI & API testing, SQL/data testing, QA/automation framework creation, CI integration, and experience working with large datasets; Financial services experience preferred.
Automated Testing in Python, Python 3, Python OOP, Selenium, T-SQL, Test Automation Frameworks, Web Service / API Test Automation, Web UI Testing Tools, AWS, AWS CloudFormation, Amazon well-architected frameworks, CI/CD, Terraform
2w
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SQL Developer, Columbia, SC( Onsite)
Columbia, South Carolina, United States
OnsiteFull Time
Genesis Healthcare
Genesis Healthcare: Provides primary and preventive medical care to underserved communities.
5+ YOE5-10 years SQL development experience with strong T-SQL and Microsoft SQL Server skills, SQL Server Agent, ETL knowledge, exposure to Azure SQL/Snowflake, Python/PowerShell preferred, strong analytical and troubleshooting skills. Bachelor's degree required.
T-SQL, Microsoft SQL Server, SQL Server Agent, Python, PowerShell, Azure SQL, Snowflake, ChatGPT, Copilot Studio
1mo
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Technical Lead Engineer
Davidson or Tyler or Minneapolis or Columbia or La Crosse
$124k-$173k/yr HybridFull Time
Trane Technologies
Trane TechnologiesNYSE: TT: Global provider of heating, ventilation, and air conditioning solutions.
5+ YOE2+ Mgmt5+ years data analytics experience; leadership; strong SQL/ETL/ELT, Python/R, Spark; cloud platforms; stakeholder management.
SQL, T-SQL, PLSQL, R, Python, Apache Spark, ETL, ELT, Apache Airflow, data warehousing, data lineage, GCP, AWS, Informatica, Oracle
1mo
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VCF Platform Engineer 2
Omaha or Saint Louis Park or Denver or Englewood or Orlando or Kansas City or Albuquerque or Portland or Salem or Pittsburgh or Austin or Dallas or Fort Worth or San Antonio or Vienna or Olympia or Columbia or St. Paul or Harrisburg or Pennington or Woodcliff Lake or Phoenix or Folsom
OnsiteFull Time
HDR
HDR: Global provider of engineering, architecture, environmental and construction services.
5+ YOE5+ years in virtualization/infrastructure/private cloud operations; hands-on VCF, SDDC Manager, vSphere administration; vSAN/NSX knowledge; scripting/automation with PowerCLI, Python, or Ansible; lifecycle ops and production troubleshooting.
VCF, SDDC Manager, vSphere, vSAN, NSX, PowerCLI, Python, Ansible, Aria Operations, Aria Automation, Aria Suite Lifecycle, API, VMware
1mo
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Staff Information Security Engineer
Denver or Greenville or Roanoke or Charleston or Raleigh or San Antonio or Des Moines or Richmond or Charlottesville or St. Louis or Cedar Rapids or Waco or Canonsburg or Greensboro or Little Rock or Lubbock or Kansas City or Knoxville or Omaha or Charleston or Wilmington or Dallas or Albuquerque or Charlotte or Waynesboro or Lincoln or Columbia
$116k-$140k/yr HybridFull Time
Segra
Segra: Provider of fiber-based connectivity and managed technology solutions for businesses.
10+ YOE10+ years related experience, bachelor’s degree or equivalent, strong security and telecom protocol knowledge, scripting (Python or PowerShell), SIEM/Splunk, IAM, cloud security (AWS/Azure), IaC/automation, incident response, and compliance frameworks (NIST/ISO).
Python, PowerShell, Splunk, Splunk ES, Terraform, Ansible, git, AWS, Microsoft Azure, Microsoft Office 365, BurpSuite, Entra, Intune, RADIUS, TACACS+, AD, LDAP, Kerberos, NIST CSF, NIST 800-53, ISO 27001, IaaS, EDR, MDR, XDR, DLP
2d
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Sr. Specialist, Vehicle Commissioning Systems Engineer
Columbia, South Carolina, United States
$110k-$135k/yr OnsiteFull Time
Scout Motors
Scout Motors: Designs and manufactures all-electric rugged SUVs and trucks.
8+ YOE8+ years automotive or manufacturing engineering experience, bachelor\u0002s degree (masters preferred), strong E/E architecture and diagnostics knowledge, experience with ECU flashing, UDS/CAN/LIN, and programming (Python, C#, C++, Java).
UDS, ISO 14229, CAN, LIN, FlexRay, Ethernet, Python, C#, C++, Java, CI/CD
1mo
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Software Development Engineer in Test (SDET) (Atlanta, GA, US)
Fort Mill or Austin or Atlanta or Chicago
$73k-$88k/yr HybridFull Time
Capgemini
CapgeminiEuronext Paris: CAP: Provides global IT consulting and digital transformation services.
7+ YOEBachelor's in CS/CE required; 7+ years as QA Engineer/SDET; hands-on Playwright experience required; proficiency in Python, TypeScript, Java/JavaScript or .NET; experience with UI/API automation, SQL, JIRA, Zephyr, and Confluence.
Playwright, Cursor AI, Model Context Protocol (MCP), Python, TypeScript, .NET, Cucumber, Atlassian JIRA, Zephyr, Confluence, Selenium, Java, JavaScript, SQL, Appium, TestNG, Saucelabs, Git, SVN, AWS, Azure, BDD
3mo
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Principal Engineer (Claremont, North Carolina, United States)
Claremont, North Carolina, United States
OnsiteFull Time
Vistance Networks
Vistance NetworksNASDAQ: VISN: Provides networking and broadband infrastructure solutions globally.
10+ YOEElectrical engineer with 10+ years experience in copper Ethernet cabling, hybrid fiber‑power systems, and signal integrity; hands-on lab and cross-functional collaboration.
Network analyzers, Oscilloscopes, Power supplies, Data loggers, MATLAB, Python
4w
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.NET Full Stack Architect (AWS) (On Site)
Fort Mill, South Carolina, United States
$102k-$195k/yr OnsiteFull Time
Cognizant
CognizantNASDAQ: CTSH: Provides IT consulting and technology services to global enterprises.
18+ YOEE2E Solution Architect with 18+ years experience; expertise in .NET Core, SQL, AWS; prompt engineering with LLMs; knowledge of AWS Bedrock, OpenSearch, S3, Kubernetes, Lambda; Python preferred; US work authorization required.
.NET Core, .NET, SQL, AWS, Copilot, LLM, Cursor, Microsoft Visual Studio Code, Python, AWS Bedrock, OpenSearch, AWS S3, Kubernetes, AWS Lambda
1mo
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Research Coordinator
Richland County or Columbia
OnsiteFull Time
State of South Carolina
State of South Carolina: Providing government administration and public services for South Carolina.
Master's in a health-related field required; conduct literature reviews, manage and analyze quantitative data, provide biostatistics/statistical consulting, and proficiency with SAS, R, or Python and quantitative/AI/ML methods.
SAS, R, Python

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