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6,192 senior python engineer jobs at 1,214 companies in South San Francisco, CA

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Senior Software Engineer - Python
Raleigh or San Francisco
$110k-$270k/yr RemoteFull Time
Veeva Systems
Veeva SystemsNYSE: VEEV: Cloud-based software solutions for the global life sciences industry.
5+ YOE5+ years software development with production-level Python; experience building high-scale enterprise SaaS cloud applications; proven scalability and architecture skills; hands-on with Python, Git, FastAPI, Pydantic; strong communication and mentorship; unrestricted US work authorization.
Python, Git, FastAPI, Pydantic
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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Python Django Developer
San Jose or Morrisville
$94k-$140k/yr OnsiteFull Time
Tata Consultancy Services
Tata Consultancy ServicesNational Stock Exchange of India: TCS: Global provider of IT services, consulting, and business solutions.
10+ YOERequires 10+ years of software engineering experience, 5+ years with Python, and experience with Django and Nginx. U.S. citizenship or qualifying work authorization is required for federal engagements.
Python, Django, Nginx, AWS GovCloud, FedRAMP
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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Principal Python Engineer (Modeling & Simulation)
San Francisco or Boston or United States
HybridFull Time
Code Metal
Code Metal: Verifiable AI-powered code translation for mission-critical industries.
7+ YOE7+ years Python software development, experience with scalable APIs, Docker, cloud distributed systems, stakeholder-driven design, SDLC best practices; eligible for U.S. Top Secret clearance.
Python, Docker, REST, GraphQL, gRPC, AWS, GCP, Azure
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Senior Software Development Engineer in Test (Python Automation)
San Jose, California, United States
$148k-$296k/yr HybridFull Time
Nutanix
NutanixNASDAQ: NTNX: Sells cloud software and hyperconverged infrastructure for enterprises.
8+ YOE8+ years experience in test engineering; strong Python automation, Kubernetes/Docker, test automation, cloud/infrastructure testing.
Python, Kubernetes, Docker, Postman, JMeter
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Senior Production Engineer
San Francisco or Sunnyvale
$209k-$253k/yr OnsiteFull Time
Crusoe
Crusoe: Provides energy-efficient cloud infrastructure powered by stranded and renewable energy.
Senior production engineer with distributed systems experience, hands-on with large language models, SRE mindset, and strong programming skills (Python, Go, Java, or C++), Kubernetes knowledge, and collaborative skills.
Python, Go, Java, C++, Kubernetes
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Senior Staff Engineer, Developer Infrastructure & Experience
Palo Alto, California, United States
OnsiteFull Time
Hippocratic AI
Hippocratic AI: Develops safety-focused generative AI for autonomous clinical healthcare conversations.
12+ YOESenior staff engineer with 12+ years of software engineering experience, backend fluency in Python/Go/Java, CI/CD ownership, and production deployments with feature flags and progressive rollouts; strong design and safety-focused engineering.
Python, Go, Java, CI/CD, Feature flags, Canary deployments, Blue/Green, Observability, AI-assisted development tools
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3mo
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Senior Physical Design Engineer
Saratoga, California, United States
$120k-$220k/yr OnsiteFull Time
E-Space
E-Space: Builds sustainable LEO satellite networks for global IoT connectivity
8+ YOESenior Physical Design Engineer with 8+ years in ASIC/SoC physical design; Cadence Innovus expertise; floorplanning, CTS, routing; timing closure; scripting (Python/Tcl).
Cadence Innovus, Synopsys ICC2, Mentor Calibre, Tcl, Python, Verilog, SystemVerilog, UVM, VHDL
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Senior Hardware Engineer
Santa Clara, California, United States
$180k-$326k/yr OnsiteFull Time
Pure Storage
Pure StorageNYSE: PSTG: Provides all-flash enterprise data storage and management solutions.
Senior hardware engineer with expert hardware design, x86 architecture, high-speed SI, validation automation, and scripting across PCIe and Ethernet.
Python, Bash, ECAD tools, Oscilloscopes, Bus analyzers
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Senior Performance Engineer, Data Protection & Security Platform Engineering
Santa Clara, California, United States
$179k-$199k/yr OnsiteFull Time
Cohesity
Cohesity: AI-powered data security and management software provider.
5+ YOESenior performance engineer with 5+ years in distributed systems; strong Golang/Python; experience with storage, cloud, and security platforms.
Golang, Python, Automation, Performance tooling
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Senior Reliability Engineer
San Francisco, California, United States
$150k-$180k/yr OnsiteFull Time
Eight Sleep
Eight Sleep: Develops smart mattresses and temperature-regulated sleep technology.
5+ YOE5+ years reliability engineering in electromechanical systems; experience with DOE, FMEA, Weibull, SPC; Python/MATLAB; hardware test equipment; strong collaboration.
Python, MATLAB, LabVIEW, JMP
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Senior Mechanical Engineer
San Francisco, California, United States
$165k-$227k/yr RemoteFull Time
Juul Labs
Juul Labs: Produces electronic vaporizers and nicotine pods for adult smokers.
8+ YOE8+ years mechanical engineering; experience with medical devices or regulated products; overseas supplier collaboration; Python proficiency; 3D MCAD (SolidWorks) and EC/mechanical integration.
Python, SolidWorks, 3D CAD, FEA, CFD, DFMEA, Design of Experiments
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Senior Battery Engineer
Palo Alto, California, United States
$211k-$224k/yr OnsiteFull Time
Wing
WingNASDAQ: GOOGL: Autonomous drone delivery service for small packages and logistics
8+ YOE8+ years in battery engineering; BS in a technical field; aerospace/robotics/EV experience; cross-functional leadership; data analysis in Python/MATLAB; thermal management expertise.
Python, MATLAB, Battery modeling, Thermal management, Data analysis
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Senior Engineer, Design Evaluation Engineering
San Jose, California, United States
$157k-$188k/yr OnsiteFull Time
Analog Devices
Analog DevicesNASDAQ: ADI: Designs and manufactures semiconductors for signal processing and power management.
1+ YOEMaster’s degree in Electrical Engineering and 1 year of relevant design evaluation experience; proficient in C#/C++, Python, and PCB design tools; able to automate tests and analyze results.
C#, C++, Python, Visual Studio, OrCAD, Cadence Allegro, Microsoft Office, PCB schematic capture, PCB layout
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Python Test Automation Engineer
Cupertino, California, United States
$140k-$150k/yr OnsiteFull Time
EPAM Systems
EPAM SystemsNYSE: EPAM: Provides global digital platform engineering and software development services.
Bachelor's degree in CS/CE/EE/ME or related field; proven Python test automation and robotic fixture experience; expertise with Git/GitHub/GitLab, UNIX/Python tools, and Jenkins; sensor systems knowledge; Master's degree is a plus.
Jenkins, UNIX, Python, Git, GitHub, GitLab, LinkedIn Learning
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2mo
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Senior Product Development Engineer - Boards
Santa Clara, California, United States
$136k-$259k/yr OnsiteFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Designs GPU-accelerated computing and artificial intelligence hardware.
5+ YOESenior engineer with 5+ years in PCB/design, board assembly, high-speed interfaces, and product development; requires electrical engineering or computer science background.
PCB design tools, High-speed interfaces, Python, C, C++, Oscilloscopes, Multimeters, Scripting, Power Integrity
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Senior Applied AI Engineer
San Francisco, California, United States
OnsiteFull Time
Alterion
Alterion: Building a control plane for enterprise AI agents.
5+ YOE5+ years in software/ML engineering; strong Python; production services; LLMs experience; model evaluation and monitoring; PyTorch or similar.
Python, PyTorch, LLMs, Machine Learning Pipelines, APIs
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
Tyba
Tyba: AI software for modeling and operating renewable energy projects.
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
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Senior Software Engineer, Platform Engineering
San Mateo, California, United States
$130k-$200k/yr OnsiteFull Time
IXL Learning
IXL Learning: Provides personalized digital learning platforms and educational resources.
6+ YOE6+ years in software/platform engineering; proficient in Java/C++/Python/Go; cloud (AWS/GCP); Docker/Kubernetes; backend systems; observability; strong collaboration; quick learner.
Java, C++, Python, Go, AWS, GCP, Docker, Kubernetes, Observability
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