691 senior python developer jobs at 247 companies in Lancaster, CA

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
1mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
1mo
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Python Test Automation Engineer
Los Angeles, California, United States
$140k-$150k/yr OnsiteFull Time
EPAM Systems
EPAM SystemsNYSE: EPAM: Provides global digital platform engineering and software development services.
Bachelor's in a relevant engineering or CS field; proven experience building Python-based test automation frameworks, robotic automation fixtures integration, Git/GitHub/GitLab, UNIX, and Jenkins; sensor validation experience; Master's degree preferred.
Python, UNIX, Jenkins, Git, GitHub, GitLab, CI/CD, Anthropic Claude, Claude Code, LinkedIn Learning
1mo
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
Tyba
Tyba: AI software for modeling and operating renewable energy projects.
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
2mo
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Senior Backend Engineer (Python) - Content Understanding
San Francisco or Atlanta or Austin or Boston or Chicago or Dallas or Denver or Houston or Jacksonville or Los Angeles or Miami or New York City or Phoenix or Portland or Sacramento or Salt Lake City or San Diego or Seattle or Washington, D.C. or Ottawa or Toronto or Vancouver or Mexico City
$120k-$228k/yr HybridFull Time
Scribd
Scribd: Subscription-based digital library for e-books, audiobooks, and documents.
7+ YOE7+ years software engineering; Python 5+ years; distributed systems; AWS; Terraform; leadership; bachelor’s in CS.
Python, Scala, Airflow, Spark, Databricks, Terraform, AWS, SQS, SNS, CloudWatch, Datadog
1mo
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Senior Software Engineer
Los Angeles or Washington or San Francisco or San Diego or Seattle or London
$130k-$220k/yr OnsiteFull Time
CHAOS Industries
CHAOS Industries: Develops advanced radar and sensing systems for modern defense.
3+ YOE3+ years software development; strong Python; Azure cloud; on-call production support; must be a U.S. Person; ability to obtain security clearance.
Python, Azure, Git, CI/CD, Docker, Kubernetes, TypeScript, Java, Bash, Rust, Node.js
3mo
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Senior Game Engineer, GenAI - Games
Los Angeles or Los Gatos
$280k-$400k/yr OnsiteFull Time
Netflix
NetflixNASDAQ: NFLX: Global video streaming and media production service.
5+ YOE5+ years game development; GenAI experience; Proficient in C++/C#, Unity or Unreal; Python; systems thinking; passion for innovation.
C++, C#, Unity, Unreal, Python
1mo
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Senior Software Engineer - Safety Platform
San Francisco or Los Angeles
$196k-$221k/yr HybridFull Time
Discord
Discord: A platform providing voice, video, and text communication services.
5+ YOE5+ years in software development; backend focus; proficiency in Python, Rust, or TypeScript; experience with production services at scale; distributed systems; cloud (GCP/AWS); strong debugging, observability, and cross-functional collaboration.
Python, Rust, TypeScript, GCP, AWS, Observability tools, Distributed systems
1mo
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Senior Software Engineer
Los Angeles, California, United States
$180k-$200k/yr OnsiteFull Time
Motorola Solutions
Motorola SolutionsNYSE: MSI: Provides mission-critical communications and public safety technology.
8+ YOE8+ years software engineering; 6+ years Python/NodeJS; Linux/DevOps; Docker/Kubernetes; Jira/Azure DevOps; US citizen with ability to obtain security clearance.
Python, Node.js, Linux, DevOps, Docker, Kubernetes, Jira, Azure DevOps
2mo
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Senior Software Engineer (Burbank, CA, US, 91505)
Burbank, California, United States
$124k-$170k/yr OnsiteFull Time
Paramount
ParamountNASDAQ: PSKY: Produces and distributes media content across global entertainment platforms.
7+ YOE7+ years software engineering; 5+ years with Golang, Java, Python; microservices; cloud (OCI, GCP); AI tooling in development; BS/MS in CS or related field.
Golang, Java, Python, Docker, Kubernetes, Oracle Cloud Infrastructure, OCI, Google Cloud, GCP, AI tools, prompt engineering, Cursor, Anthropic Claude
1mo
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Senior Software Engineer, Data Systems (Python)
Canada or United States or San Francisco or Los Angeles
$170k-$200k/yr RemoteFull Time
Northbeam
Northbeam: Marketing intelligence and attribution platform for eCommerce brands.
5+ YOE5+ years in data/software/integration engineering; strong Python, ETL, API/REST/GraphQL/Webhooks, auth flows; SQL and BigQuery; Airflow; Docker/Kubernetes; strong problem solving and observability skills.
Python, ETL, APIs, REST, GraphQL, Webhooks, OAuth 2.0, API keys, SQL, BigQuery, Airflow, Docker, Kubernetes
2w
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Staff Systems Engineer (C++/Python)
New York or Los Angeles County
$220k-$260k/yr RemoteFull Time
NBCUniversal
NBCUniversalNASDAQ: CMCSA: Produces and distributes entertainment content and theme park experiences.
5+ YOEBachelor's in CS/Engineering/Math, 5+ years industry experience, strong C++ systems development, familiarity with machine learning/computer vision, Git and Unix shell proficiency, experience deploying/testing on cloud and large geospatial datasets.
C++, Python, Git, Mercurial, CMake, Linux, macOS, bash, Unreal Engine
2mo
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Senior Security Engineer
Austin or Chicago or Dallas or Denver or Los Angeles or San Diego or San Francisco
$131k-$169k/yr HybridFull Time
Karbon
Karbon: Practice management software for accounting firms.
4+ YOESenior Security Engineer with 4+ years in security or development; strong communication; cloud and AI experience; hands-on with security tooling and threat modelling.
DotnetCSharp, JavaScript, React, EmberJS, Python, Azure, AWS, GCP, PowerShell, Bash, GitHub Copilot, Burp Suite
1mo
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Senior Software Engineer, Match Team
New York or Los Angeles
$180k-$210k/yr HybridFull Time
Enigma
Enigma: Provides data and intelligence on small business financial health.
5+ YOE5+ years software engineering; strong Python; cloud (AWS); backend systems/APIs; experience with distributed systems and data delivery.
Python, Typesense, AWS, Docker, Terraform, Elasticsearch, OpenSearch, FAISS
2mo
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Senior Software Engineer, Air AI
Mountain View or Los Angeles or San Francisco or New York City
$170k-$230k/yr HybridFull Time
Commure
Commure: AI-powered software platform for healthcare workflow and administrative automation.
4+ YOE4+ years software engineering; strong fullstack Python backend and TypeScript/React frontend; Docker and Kubernetes; experience with LLM APIs; production AI features; able to ship quickly.
Python, TypeScript, React, Docker, Kubernetes
1mo
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Senior Software Engineer
Los Angeles or Vancouver
$193k-$297k/yr HybridFull Time
Electronic Arts
Electronic ArtsNASDAQ: EA: Develops and publishes video games and interactive entertainment software.
5+ YOE5+ years software development experience, strong C/C++ and Python skills, experience with large shared codebases, profiling/optimization experience, bachelor's in CS/Engineering or equivalent.
C/C++, Python
3mo
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Senior ML Engineer
Los Angeles, California, United States
$180k-$200k/yr RemoteFull Time
Quilter
Quilter: Automates printed circuit board layout using physics-driven AI.
4+ YOE4+ years in ML/optimization; strong ML & optimization fundamentals; production PyTorch; autonomous in ambiguous spaces; strong communication.
PyTorch, CUDA C++, Python
3mo
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Senior Test Engineer, HITL
Los Angeles, California, United States
OnsiteFull Time
Observable Space
Observable Space: Developing integrated hardware and software for persistent space observation.
5+ YOE5+ years in test engineering, embedded systems, or systems-level development; strong C/C++/Python; experience with HITL/HIL testing; embedded interfaces; test automation and CI/CD.
C/C++, Python, I2C, SPI, UART, CAN, Ethernet, Oscilloscopes, Logic analyzers, Multimeters, Embedded Linux, RTOS
1mo
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Senior Software Engineer, SDK Foundations - Publishing Platform
Los Angeles, California, United States
$162k-$227k/yr OnsiteFull Time
Riot Games
Riot Games: Developing and publishing competitive multiplayer video games.
4+ YOE4+ years C++ with Unreal Engine; large codebase experience; client SDK development; on-call rotation.
C++, Unreal Engine, Python, TypeScript
2w
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Senior Backend Engineer
Los Angeles or New York City or San Francisco
$170k-$200k/yr HybridFull Time
Tatari
Tatari: A platform for buying and measuring TV advertising campaigns.
6+ YOE6+ years software development (Python required), 4+ years building distributed systems and modern data stacks, deep SQL and data modeling, experience with LLMs and agentic coding tools, strong communication and cross-team collaboration.
Python, Cursor, Copilot, Cody, RDS, Databricks, Spark, Redshift, Kafka, Airflow, dbt, SQL, REST, gRPC, GraphQL
1mo
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Senior Flight Software Engineer (Remote)
Los Angeles, California, United States
$185k-$215k/yr RemoteFull Time
Apex
Apex: Mass-manufactures standardized satellite buses for commercial and government use.
8+ YOE8+ years flight software experience; US Person; BS in CS/EE or equivalent; Python, C++, Rust; real-time distributed systems; embedded Linux (Yocto); CCSDS/ECSS familiarity; network protocols (TCP/IP, UDP); Protobuf; encryption.
Python, C++, Rust, Embedded Linux, Yocto, CCSDS, ECSS, Protobuf, TCP/IP, UDP, Encryption