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1,244 senior python developer jobs at 322 companies in Simi Valley, CA

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
1mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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1mo
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Python Test Automation Engineer
Los Angeles, California, United States
$140k-$150k/yr OnsiteFull Time
EPAM Systems
EPAM SystemsNYSE: EPAM: Provides global digital platform engineering and software development services.
Bachelor's in a relevant engineering or CS field; proven experience building Python-based test automation frameworks, robotic automation fixtures integration, Git/GitHub/GitLab, UNIX, and Jenkins; sensor validation experience; Master's degree preferred.
Python, UNIX, Jenkins, Git, GitHub, GitLab, CI/CD, Anthropic Claude, Claude Code, LinkedIn Learning
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1mo
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Senior Product Software Engineer (Python)
San Francisco or Chicago or Los Angeles
$160k-$200k/yr HybridFull Time
Tyba
Tyba: AI software for modeling and operating renewable energy projects.
5+ YOE5+ years full-stack engineering experience; strong Python and React; production GraphQL experience; willingness to learn ClojureScript; familiarity with AI-assisted coding tools; strong cross-functional communication.
Python, React, GraphQL, Strawberry, ClojureScript, Cursor, Copilot, Claude Code, Warp Agent Mode, Recharts, ECharts, dbt, Snowflake, Redshift, PyTorch, AWS, PostgreSQL, Fulcro, Tailwind CSS, Clojure, Kotlin
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2mo
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Senior Backend Engineer (Python) - Content Understanding
San Francisco or Atlanta or Austin or Boston or Chicago or Dallas or Denver or Houston or Jacksonville or Los Angeles or Miami or New York City or Phoenix or Portland or Sacramento or Salt Lake City or San Diego or Seattle or Washington, D.C. or Ottawa or Toronto or Vancouver or Mexico City
$120k-$228k/yr HybridFull Time
Scribd
Scribd: Subscription-based digital library for e-books, audiobooks, and documents.
7+ YOE7+ years software engineering; Python 5+ years; distributed systems; AWS; Terraform; leadership; bachelor’s in CS.
Python, Scala, Airflow, Spark, Databricks, Terraform, AWS, SQS, SNS, CloudWatch, Datadog
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2mo
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Senior Software Engineer, AI
El Segundo or United States
$153k-$170k/yr RemoteFull Time
ImmunityBio
ImmunityBioNASDAQ: IBRX: Develops next-generation immunotherapies for cancer and infectious diseases.
7+ YOESenior software engineer with 7+ years of experience in Python/Typescript, AI agent frameworks, and production-grade systems.
Python, TypeScript, FastAPI, Docker, LangGraph, LangChain, CrewAI, LlamaIndex, Chroma, Milvus, Weaviate, Qdrant
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1mo
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Senior Software Engineer
Los Angeles or Washington or San Francisco or San Diego or Seattle or London
$130k-$220k/yr OnsiteFull Time
CHAOS Industries
CHAOS Industries: Develops advanced radar and sensing systems for modern defense.
3+ YOE3+ years software development; strong Python; Azure cloud; on-call production support; must be a U.S. Person; ability to obtain security clearance.
Python, Azure, Git, CI/CD, Docker, Kubernetes, TypeScript, Java, Bash, Rust, Node.js
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3mo
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Senior Game Engineer, GenAI - Games
Los Angeles or Los Gatos
$280k-$400k/yr OnsiteFull Time
Netflix
NetflixNASDAQ: NFLX: Global video streaming and media production service.
5+ YOE5+ years game development; GenAI experience; Proficient in C++/C#, Unity or Unreal; Python; systems thinking; passion for innovation.
C++, C#, Unity, Unreal, Python
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1mo
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Senior Software Engineer - Safety Platform
San Francisco or Los Angeles
$196k-$221k/yr HybridFull Time
Discord
Discord: A platform providing voice, video, and text communication services.
5+ YOE5+ years in software development; backend focus; proficiency in Python, Rust, or TypeScript; experience with production services at scale; distributed systems; cloud (GCP/AWS); strong debugging, observability, and cross-functional collaboration.
Python, Rust, TypeScript, GCP, AWS, Observability tools, Distributed systems
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1mo
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Senior Software Engineer
Los Angeles, California, United States
$180k-$200k/yr OnsiteFull Time
Motorola Solutions
Motorola SolutionsNYSE: MSI: Provides mission-critical communications and public safety technology.
8+ YOE8+ years software engineering; 6+ years Python/NodeJS; Linux/DevOps; Docker/Kubernetes; Jira/Azure DevOps; US citizen with ability to obtain security clearance.
Python, Node.js, Linux, DevOps, Docker, Kubernetes, Jira, Azure DevOps
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2mo
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Senior Software Engineer (Burbank, CA, US, 91505)
Burbank, California, United States
$124k-$170k/yr OnsiteFull Time
Paramount
ParamountNASDAQ: PSKY: Produces and distributes media content across global entertainment platforms.
7+ YOE7+ years software engineering; 5+ years with Golang, Java, Python; microservices; cloud (OCI, GCP); AI tooling in development; BS/MS in CS or related field.
Golang, Java, Python, Docker, Kubernetes, Oracle Cloud Infrastructure, OCI, Google Cloud, GCP, AI tools, prompt engineering, Cursor, Anthropic Claude
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1mo
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Senior Software Engineer, Data Systems (Python)
Canada or United States or San Francisco or Los Angeles
$170k-$200k/yr RemoteFull Time
Northbeam
Northbeam: Marketing intelligence and attribution platform for eCommerce brands.
5+ YOE5+ years in data/software/integration engineering; strong Python, ETL, API/REST/GraphQL/Webhooks, auth flows; SQL and BigQuery; Airflow; Docker/Kubernetes; strong problem solving and observability skills.
Python, ETL, APIs, REST, GraphQL, Webhooks, OAuth 2.0, API keys, SQL, BigQuery, Airflow, Docker, Kubernetes
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1mo
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Senior Simulation and Modeling Engineer
Long Beach, California, United States
$148k-$204k/yr OnsiteFull Time
Relativity Space
Relativity Space: Designing and manufacturing 3D-printed rockets and launch vehicles.
5+ YOELead simulation development for 6DOF GNC, build models and solvers; 5+ yrs in engineering with C++, Python; aerospace simulations; startup environment.
C++, Rust, Python
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2w
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Staff Systems Engineer (C++/Python)
New York or Los Angeles County
$220k-$260k/yr RemoteFull Time
NBCUniversal
NBCUniversalNASDAQ: CMCSA: Produces and distributes entertainment content and theme park experiences.
5+ YOEBachelor's in CS/Engineering/Math, 5+ years industry experience, strong C++ systems development, familiarity with machine learning/computer vision, Git and Unix shell proficiency, experience deploying/testing on cloud and large geospatial datasets.
C++, Python, Git, Mercurial, CMake, Linux, macOS, bash, Unreal Engine
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2mo
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Senior Security Engineer
Austin or Chicago or Dallas or Denver or Los Angeles or San Diego or San Francisco
$131k-$169k/yr HybridFull Time
Karbon
Karbon: Practice management software for accounting firms.
4+ YOESenior Security Engineer with 4+ years in security or development; strong communication; cloud and AI experience; hands-on with security tooling and threat modelling.
DotnetCSharp, JavaScript, React, EmberJS, Python, Azure, AWS, GCP, PowerShell, Bash, GitHub Copilot, Burp Suite
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3mo
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Senior Software Engineer, Robotics
Torrance, California, United States
$141k-$194k/yr OnsiteFull Time
Divergent
Divergent: Develops digital manufacturing systems for complex vehicle structures.
5+ YOEBachelor’s in Computer Science, Robotics, or related field; 5+ years of experience; proficient in C++ and Python; knowledge of robotics concepts, planning/vision; ROS/MoveIt experience; CI/CD; Docker/Kubernetes; strong collaboration.
C++, Python, ROS, MoveIt, OpenCV, PCL, Docker, Kubernetes
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1mo
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Senior Software Engineer, Match Team
New York or Los Angeles
$180k-$210k/yr HybridFull Time
Enigma
Enigma: Provides data and intelligence on small business financial health.
5+ YOE5+ years software engineering; strong Python; cloud (AWS); backend systems/APIs; experience with distributed systems and data delivery.
Python, Typesense, AWS, Docker, Terraform, Elasticsearch, OpenSearch, FAISS
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2mo
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Senior Software Engineer, Air AI
Mountain View or Los Angeles or San Francisco or New York City
$170k-$230k/yr HybridFull Time
Commure
Commure: AI-powered software platform for healthcare workflow and administrative automation.
4+ YOE4+ years software engineering; strong fullstack Python backend and TypeScript/React frontend; Docker and Kubernetes; experience with LLM APIs; production AI features; able to ship quickly.
Python, TypeScript, React, Docker, Kubernetes
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3mo
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Senior Software Engineer (Teradyne, Agoura Hills) (Agoura Hills, CA, US)
Agoura Hills, California, United States
$162k-$259k/yr HybridFull Time
Teradyne
TeradyneNASDAQ: TER: Designs and manufactures automated test equipment and advanced robotics systems.
10+ YOE10+ years software development; embedded Linux BSP and drivers; C/C++, Python; Linux environment; Git, CMake, Yocto, Docker; hardware interfaces; cross-functional teamwork; BS in engineering; EOE.
GIT, CMake, Yocto, Docker, Linux, Python, C, C++, bash
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1mo
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Senior Software Engineer
Los Angeles or Vancouver
$193k-$297k/yr HybridFull Time
Electronic Arts
Electronic ArtsNASDAQ: EA: Develops and publishes video games and interactive entertainment software.
5+ YOE5+ years software development experience, strong C/C++ and Python skills, experience with large shared codebases, profiling/optimization experience, bachelor's in CS/Engineering or equivalent.
C/C++, Python
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3mo
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Senior ML Engineer
Los Angeles, California, United States
$180k-$200k/yr RemoteFull Time
Quilter
Quilter: Automates printed circuit board layout using physics-driven AI.
4+ YOE4+ years in ML/optimization; strong ML & optimization fundamentals; production PyTorch; autonomous in ambiguous spaces; strong communication.
PyTorch, CUDA C++, Python
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