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823 senior python developer jobs at 296 companies in Pennsylvania

PromotedHiringCafe
Founding Backend / Infra Engineer
Cupertino, CA, US
$160k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Own the crawlers, pipelines, and infrastructure powering a real-time job search engine. Strong Node.js and Python fundamentals; bonus points for security and reverse-engineering chops.
Node.js, Python, Elasticsearch, Redis
Help us #BeatIndeed & #BeatLinkedIn
PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
Help us #BeatIndeed & #BeatLinkedIn
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Python API Developer
Malvern, Pennsylvania, United States
$110k-$120k/yr OnsiteFull Time
Tata Consultancy Services
Tata Consultancy ServicesNational Stock Exchange of India: TCS: Global provider of IT services, consulting, and business solutions.
10+ YOEDesign and maintain REST APIs with Python and AWS Lambda; integrate with Amazon Aurora and DynamoDB; manage DB migrations with Liquibase; 10+ years experience and Bachelors in Computer Science required.
Python, Lambda, Aurora, DynamoDB, Liquidbase, CI/CD
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1mo
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Senior Python Development Lead
Philadelphia, Pennsylvania, United States
OnsiteFull Time
Brown Brothers Harriman
Brown Brothers Harriman: Providing global investment management, custody, and private banking services.
15+ YOE5+ Mgmt15+ years in data engineering/software development; Python/Django; ETL pipelines; data visualization; Agile; Linux; security; leads 5-6 juniors
Python, Django, SQL, Bash, JavaScript, Plotly Dash, D3.js, AG Grid, Apache Airflow, FastAPI, Linux, Git, CI/CD
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1mo
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Python/AI Product Engineer (Durham, NC, US)
Durham or Pittsburgh
HybridFull Time
ACA Group
ACA Group: Regulatory compliance and risk management solutions for financial services.
Senior/lead AI developer with Python, cloud-native AI, LangChain/LangGraph, AWS, and enterprise-grade experience.
Python, AWS, LangChain, LangGraph, cloud, LLM, APIs, microservices, databases, vector search, RAG
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2mo
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Senior Software Engineer - Python - 1099
Conshohocken, Pennsylvania, United States
RemoteTemporary
Syzygy Integration
Syzygy Integration: Develops situational awareness and tactical communication technology for defense.
10+ YOE10+ years full stack experience; Python; remote US-based role; must pass background check; U.S. citizen.
Python
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1mo
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GenAI Python Systems Engineer –Senior Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Richmond or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Spartanburg or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Tulsa or Washington or Denver or Des Moines or Detroit or Buffalo or Florham Park or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Birmingham or Fayetteville or Miami or Milwaukee or Minneapolis or Nashville or New Orleans or New York or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland
$124k-$280k/yr HybridFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
8+ YOESenior Manager level with 8+ years of experience; proficient in Python, SQL, FastAPI; cloud certifications a plus; willing to travel up to 80%; Bachelor's degree required.
Python, SQL, FastAPI, Cloud Platforms, LLM techniques, Data Warehousing, Data Lakes, IAM
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2w
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Python Developer- Quant Core Data | Experienced Hire
Bala Cynwyd, Pennsylvania, United States
OnsiteFull Time
Susquehanna International Group
Susquehanna International Group: Global quantitative trading firm specializing in proprietary financial markets.
PhD or postdoc in a quantitative field, strong high-performance Python (Cython/pybind11/numba) and large-data analysis (polars/pandas) skills, ability to translate research into production-quality code.
Python, Cython, pybind11, numba, polars, pandas
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2w
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Python Developer- Quant Core Data | Experienced Hire
Bala Cynwyd, Pennsylvania, United States
OnsiteFull Time
Susquehanna International Group
Susquehanna International Group: Global quantitative trading and market making firm.
PhD or postdoc in a quantitative field, strong high-performance Python skills (Cython/pybind11/numba), experience with large-data analysis (polars/pandas), and ability to translate research into robust engineering solutions.
Python, Cython, pybind11, Numba, polars, pandas
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2w
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Python Developer- Quant Core Data | Experienced Hire
Bala Cynwyd, Pennsylvania, United States
OnsiteFull Time
Susquehanna International Group
Susquehanna International Group: Global quantitative trading firm providing proprietary financial market liquidity.
PhD (by Summer 2026) or postdoc in a quantitative field; experience writing high-performance Python (Cython, pybind11, numba) and data analysis with polars/pandas for large datasets; ability to translate research into robust engineering solutions.
Python, Cython, pybind11, numba, polars, pandas
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1mo
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Software Engineer Principal - Ansible/Python
Pittsburgh, Pennsylvania, United States
OnsiteFull Time
PNC Financial Services
PNC Financial ServicesNYSE: PNC: Provides banking, lending, and investment services to customers.
5+ YOEExperience with Ansible, Python, backend development, distributed systems, and disaster recovery; strong automation and mentoring skills.
Ansible, Python, Celery, SQLAlchemy, SQLModel, FastAPI
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1mo
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Senior Autonomy Engineer
Mossville or Pittsburgh
$113k-$183k/yr OnsiteFull Time
Caterpillar
CaterpillarNYSE: CAT: Manufactures construction equipment, mining machinery, and industrial engines.
4+ YOESenior Autonomy Engineer with 4+ years robotics experience; localization/filters expertise; proficient in C++, Python; ROS knowledge; bachelor’s, master’s, or PhD in robotics, electrical/computer engineering, or computer science; onsite five days a week; relocation and visa sponsorship available.
C++, Python, ROS, Kalman filtering, Inertial Measurement technology, GNSS
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2mo
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Senior Software Engineer - Manage Vehicle Interfaces
Dearborn or Pittsburgh or Remote
HybridFull Time
Latitude AI
Latitude AI: Developing automated driving technology for next-generation Ford vehicles.
Strong modern C++ knowledge; unit testing with GTest/GMock; Linux development; work in a large monorepo; experience with serialization and UDP networking; Bazel tooling; Python is a plus.
C++, GTest, GMock, Bazel, Linux, UDP, LwIP, Python
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3mo
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Senior / Staff Software Engineer, Localization
San Francisco or Pittsburgh or Toronto or United States or Canada
$141k-$242k/yr HybridFull Time
Waabi
Waabi: Develops Physical AI for autonomous trucking and robotaxis.
5+ YOESenior-level localization systems engineer with expertise in state estimation, multi-sensor fusion, and real-time robotics software; strong C++/Rust, Python, and mathematical foundation; experience deploying SLAM/state estimation on real robots.
C++, Rust, Python, GTSAM, Ceres Solver, g2o
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2mo
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Senior Software Engineer, Backend
Philadelphia, Pennsylvania, United States
$160k-$210k/yr OnsiteFull Time
Perpay
Perpay: Financial platform offering interest-free shopping and credit building via payroll.
5+ YOE5+ years web apps; 2+ years leading teams; PostgreSQL; AWS; Docker/Kubernetes; Python/Django or Rails; strong communication.
JavaScript, Python, Django, Flask, React, React Native, Redux, Kubernetes, AWS, Docker, Celery, Redis, Datadog, CloudWatch
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3mo
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Senior Software Developer
Conshohocken or Portland or Bucharest or Ia\u00021si or Barcelona or Tokyo or United States
OnsiteFull Time
Suvoda
Suvoda: Software for clinical trial randomization and patient data collection.
6+ YOE6+ years software development experience, deep Python, relational databases and AWS experience, EMR not stated, Django and Angular preferred, bachelor's or equivalent experience, production-support mindset.
Python, Django, Angular, AWS, Claude Code
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2mo
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Senior Backend Engineer
Pittsburgh, Pennsylvania, United States
$25-$60/hr RemoteContract
Branding Brand
Branding Brand: Develops mobile commerce platforms and applications for enterprise retailers.
4+ YOESenior backend engineer with 4+ years' experience in Java (Spring/WebFlux) and Python; PostgreSQL; Databricks; AWS/Azure; CI/CD; REST APIs; strong problem solving and communication.
Java, Spring Boot, REST, Python, Databricks, PostgreSQL, SQL, Angular, Azure, AWS, Kubernetes, Redis, Apigee, CI/CD, DevOps, Databricks notebooks, K6
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2mo
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Senior Embedded Software Engineer
Boston or Las Vegas or Pittsburgh
$149k-$199k/yr HybridFull Time
Motional
Motional: Develops autonomous vehicle technology for driverless ride-hailing and delivery.
Embedded software in C/C++, Python; embedded Linux/RTOS; networking; testing; can lead initiatives; collaboration with cross-functional teams; hybrid/remote work.
C, C++, Python, Embedded Linux, RTOS, Linux, CAN, Ethernet, ARM Cortex, Bazel, PyTorch, TensorFlow, ONNX
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2w
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Senior Backend Developer
Tennessee or Idaho or Arkansas or Nebraska or Louisiana or Missouri or Texas or Indiana or Nevada or Kentucky or Mississippi or Florida or South Carolina or West Virginia or New Mexico or North Carolina or Oklahoma or South Dakota or Alabama or Utah or Kansas or Iowa or Pennsylvania or Michigan or Wisconsin or Georgia or Montana or Arizona or North Dakota or Wyoming
RemoteFull Time
Sedgwick
Sedgwick: Provides global insurance claims management and risk services.
7+ YOEBachelor's in CS/Engineering, 7+ years backend development, proficiency in Java/C#/Python/Node.js, REST/microservices, legacy integrations, SQL/NoSQL, Docker/Kubernetes, Kafka/RabbitMQ, API security and observability.
Java, C#, Python, Node.js, SOAP, XML, JSON, SQL Server, Oracle, PostgreSQL, Redis, Docker, Kubernetes, Kafka, RabbitMQ, OpenAPI/Swagger, JDBC/ODBC, OAuth2, JWT, mutual TLS, SAML, API gateways, service meshes, message queues
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2w
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Senior Software Developer
Pittsburgh or United States
RemoteFull Time
Bizowie
Bizowie: Cloud-based ERP software for mid-market manufacturers and distributors.
5+ YOE5+ years professional software development; strong skills in a dynamic language (Perl, Python, Ruby, PHP, JavaScript); solid SQL and relational database skills; experience deploying/operating on AWS; strong written communication for remote work.
Perl, Python, Ruby, PHP, JavaScript, SQL, AWS
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1mo
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Software Developer, Senior
Chambersburg, Pennsylvania, United States
$145k/yr HybridFull Time
AGE Solutions
AGE Solutions: Technology consulting and IT services for government agencies.
10+ YOEBachelor's degree, 10+ years software development, 3–5+ years full-stack web experience (React/Vue/Angular and Node.js/Python/Java), DoD Secret clearance, DoD 8140 qualification, cloud and CI/CD expertise.
React, Vue, Angular, Node.js, Python, Java, AWS, Azure, RESTful APIs, CI/CD
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2mo
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Senior Software Engineer
Pittsburgh, Pennsylvania, United States
HybridFull Time
Smith & Nephew
Smith & NephewLondon Stock Exchange: SN: Develops medical equipment for tissue repair, regeneration, and replacement.
5+ YOE5-8 years in design and implementation of complex software components; strong SDL, CUDA, Vulkan, OpenGL; medical image processing and visualization; UI rendering modernization.
SDL, CUDA, Vulkan, OpenGL, Image processing, OpenCV, ITK, C++, Python
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